Phosphorylation of cardiac myosin heavy chains (see MYH7B, MIM 609928) and light chains (see MYL2, MIM 160781) by a kinase, such as MYLK3, potentiates the force and rate of cross-bridge recruitment in cardiac myocytes (Chan et al., 2008 [PubMed 18202317]).[supplied by OMIM, Jul 2008] See more...

Aliases for MYLK3 Gene

Aliases for MYLK3 Gene

  • Myosin Light Chain Kinase 3 2 3 4 5
  • MLCK 2 3 4
  • Cardiac-MLCK 3 4
  • MLC Kinase 2 3
  • CaMLCK 2 3
  • Cardiac-MyBP-C Associated Ca/CaM Kinase 3
  • Cardiac-MyBP-C-Associated Ca/CaM Kinase 4
  • Putative Myosin Light Chain Kinase 3 3
  • EC 2.7.11.18 4
  • EC 2.7.11 51
  • MLCK2 3
  • MYLK3 5

External Ids for MYLK3 Gene

Previous GeneCards Identifiers for MYLK3 Gene

  • GC16M045293
  • GC16M046736
  • GC16M032625

Summaries for MYLK3 Gene

Entrez Gene Summary for MYLK3 Gene

  • Phosphorylation of cardiac myosin heavy chains (see MYH7B, MIM 609928) and light chains (see MYL2, MIM 160781) by a kinase, such as MYLK3, potentiates the force and rate of cross-bridge recruitment in cardiac myocytes (Chan et al., 2008 [PubMed 18202317]).[supplied by OMIM, Jul 2008]

GeneCards Summary for MYLK3 Gene

MYLK3 (Myosin Light Chain Kinase 3) is a Protein Coding gene. Diseases associated with MYLK3 include Hypoplastic Right Heart Syndrome and Dilated Cardiomyopathy. Among its related pathways are Focal Adhesion and Apelin signaling pathway. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is MYLK2.

UniProtKB/Swiss-Prot Summary for MYLK3 Gene

  • Kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility (By similarity).

Tocris Summary for MYLK3 Gene

  • Myosin Light Chain Kinases (MLCKs) are a group of protein serine/threonine kinases that are currently divided into two subtypes. MLCK1 is found in smooth muscle and phosphorylates myosin II regulatory light chains at Ser19. MLCK2 is located in the striated muscle.

Gene Wiki entry for MYLK3 Gene

Additional gene information for MYLK3 Gene

No data available for CIViC Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MYLK3 Gene

Genomics for MYLK3 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MYLK3 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J046745 Promoter/Enhancer 2 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 616.4 +42.7 42694 5 TEAD4 LEF1 IKZF1 ZIC2 RFX1 PKNOX1 RXRB PBX2 ZNF341 FOXJ2 MYLK3 SHCBP1 ORC6 VPS35 GPT2 lnc-MYLK3-1 lnc-MYLK3-2 LOC100130180
GH16J046788 Promoter/Enhancer 1.9 FANTOM5 Ensembl ENCODE CraniofacialAtlas 600.7 +0.4 372 2.1 BRCA1 GATAD2A TFE3 SOX13 POLR2A ZNF7 BACH1 LARP7 ZNF143 ZIC2 ENSG00000260782 LOC100130180 MYLK3 lnc-MYLK3-2 lnc-ORC6-2 SHCBP1 ORC6
GH16J046742 Enhancer 1.4 FANTOM5 ENCODE CraniofacialAtlas dbSUPER 33.2 +47.2 47157 1.7 ZNF512 RFX1 IKZF1 FOXA1 ZSCAN4 PKNOX1 ZNF740 BRD9 DPF2 HDAC1 MYLK3 SHCBP1 lnc-MYLK3-1 lnc-MYLK3-2 LOC100130180 ORC6
GH16J046686 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 10.9 +101.2 101225 6 BRCA1 SP1 CREB1 GATAD2A CTCF PRDM10 TFE3 RFX1 NFKBIZ ZNF692 ORC6 VPS35 lnc-MYLK3-3-002 GPT2 SHCBP1 MYLK3 ANKRD26P1
GH16J046758 Enhancer 0.6 FANTOM5 dbSUPER 24.5 +31.9 31896 0.1 ZSCAN4 ZMYM3 MYLK3 lnc-MYLK3-2 LOC100130180 lnc-MYLK3-1 ORC6
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MYLK3 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for MYLK3

Top Transcription factor binding sites by QIAGEN in the MYLK3 gene promoter:
  • Egr-3
  • GATA-1
  • GATA-2
  • GATA-3
  • GATA-6
  • Roaz
  • RREB-1
  • SREBP-1a
  • SREBP-1b
  • SREBP-1c

Genomic Locations for MYLK3 Gene

Genomic Locations for MYLK3 Gene
chr16:46,702,282-46,790,407
(GRCh38/hg38)
Size:
88,126 bases
Orientation:
Minus strand
chr16:46,736,194-46,824,319
(GRCh37/hg19)
Size:
88,126 bases
Orientation:
Minus strand

Genomic View for MYLK3 Gene

Genes around MYLK3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MYLK3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MYLK3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MYLK3 Gene

Proteins for MYLK3 Gene

  • Protein details for MYLK3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q32MK0-MYLK3_HUMAN
    Recommended name:
    Myosin light chain kinase 3
    Protein Accession:
    Q32MK0
    Secondary Accessions:
    • B5BUL9
    • B7Z5U8
    • Q32MK1
    • Q96DV1

    Protein attributes for MYLK3 Gene

    Size:
    819 amino acids
    Molecular mass:
    88393 Da
    Cofactor:
    Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAI09098.2; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305}; Sequence=CAC42766.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};

    Alternative splice isoforms for MYLK3 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MYLK3 Gene

Selected DME Specific Peptides for MYLK3 Gene

Q32MK0:
  • NLIQLYDAFESK
  • GGELFDR
  • EKLKVNFGTPEFL
  • IIDFGLA
  • LHLDLKP
  • DMWSVGVI

Post-translational modifications for MYLK3 Gene

Other Protein References for MYLK3 Gene

Domains & Families for MYLK3 Gene

Gene Families for MYLK3 Gene

Protein Domains for MYLK3 Gene

Suggested Antigen Peptide Sequences for MYLK3 Gene

GenScript: Design optimal peptide antigens:
  • MLCK protein (B5BUL9_HUMAN)
  • cDNA FLJ50066, highly similar to Homo sapiens cardiac-MyBP-C associated Ca/CaM kinase (MLCK), mRNA (B7Z5U8_HUMAN)
  • Cardiac-MyBP-C-associated Ca/CaM kinase (MYLK3_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q32MK0

UniProtKB/Swiss-Prot:

MYLK3_HUMAN :
  • Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Family:
  • Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
genes like me logo Genes that share domains with MYLK3: view

Function for MYLK3 Gene

Molecular function for MYLK3 Gene

UniProtKB/Swiss-Prot Function:
Kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility (By similarity).
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=[myosin light chain]-L-serine + ATP = [myosin light chain]-O-phospho-L-serine + ADP + H(+); Xref=Rhea:RHEA:22004, Rhea:RHEA-COMP:13684, Rhea:RHEA-COMP:13685, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616, ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.18;.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=[myosin light chain]-L-threonine + ATP = [myosin light chain]-O-phospho-L-threonine + ADP + H(+); Xref=Rhea:RHEA:53900, Rhea:RHEA-COMP:13686, Rhea:RHEA-COMP:13687, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013, ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216; EC=2.7.11.18;.

Enzyme Numbers (IUBMB) for MYLK3 Gene

Gene Ontology (GO) - Molecular Function for MYLK3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0004672 protein kinase activity IEA --
GO:0004674 protein serine/threonine kinase activity IEA --
GO:0004683 calmodulin-dependent protein kinase activity ISS --
GO:0004687 myosin light chain kinase activity ISS --
genes like me logo Genes that share ontologies with MYLK3: view
genes like me logo Genes that share phenotypes with MYLK3: view

Animal Models for MYLK3 Gene

MGI Knock Outs for MYLK3:

Animal Model Products

  • Taconic Biosciences Mouse Models for MYLK3

CRISPR Products

miRNA for MYLK3 Gene

miRTarBase miRNAs that target MYLK3

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MYLK3

No data available for Phenotypes From GWAS Catalog , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for MYLK3 Gene

Localization for MYLK3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MYLK3 Gene

Cytoplasm.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MYLK3 gene
Compartment Confidence
cytoskeleton 4
cytosol 4
plasma membrane 2
extracellular 2
nucleus 2
mitochondrion 1
endoplasmic reticulum 1
endosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoplasm (2)
  • Vesicles (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for MYLK3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IBA,ISS --
GO:0005829 cytosol ISS --
GO:0015629 colocalizes_with actin cytoskeleton IBA 21873635
genes like me logo Genes that share ontologies with MYLK3: view

Pathways & Interactions for MYLK3 Gene

PathCards logo

SuperPathways for MYLK3 Gene

SuperPathway Contained pathways
1 Oxytocin signaling pathway
2 Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases
.49
.49
3 Immune response CCR3 signaling in eosinophils
.51
.51
4 Apelin signaling pathway
5 Calcium signaling pathway
genes like me logo Genes that share pathways with MYLK3: view

Pathways by source for MYLK3 Gene

1 Sino Biological pathway for MYLK3 Gene
6 GeneGo (Thomson Reuters) pathways for MYLK3 Gene
  • Cell adhesion Integrin-mediated cell adhesion and migration
  • Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases
  • Cytoskeleton remodeling Role of PKA in cytoskeleton reorganisation
  • Immune response CCR3 signaling in eosinophils
  • Inhibitory action of Lipoxins on neutrophil migration

Gene Ontology (GO) - Biological Process for MYLK3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002528 regulation of vascular permeability involved in acute inflammatory response IMP 18390750
GO:0006468 protein phosphorylation ISS --
GO:0016310 phosphorylation IEA --
GO:0045214 sarcomere organization IBA,ISS --
GO:0048769 sarcomerogenesis ISS --
genes like me logo Genes that share ontologies with MYLK3: view

No data available for SIGNOR curated interactions for MYLK3 Gene

Drugs & Compounds for MYLK3 Gene

(10) Drugs for MYLK3 Gene - From: DrugBank, ApexBio, HMDB, Tocris, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
fostamatinib Approved, Investigational Pharma Target, inhibitor Kinase Inhibitors 0
Magnesium Approved, Experimental, Investigational Pharma 0
Omecamtiv mecarbil Investigational Pharma Cardiac myosin activator 0
ATP Investigational Nutra Agonist, Activator, Partial agonist, Antagonist, Full agonist, Gating inhibitor, Pore Blocker, Potentiation 0
Calcium Nutra 6556

(6) Additional Compounds for MYLK3 Gene - From: HMDB and Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
ADP
  • 5'-Adenylphosphoric acid
  • Adenosine 5'-diphosphate
  • ADENOSINE-5'-diphosphATE
  • H3ADP
  • 5'-Adenylphosphate
Agonist, Full agonist, Partial agonist, Gating inhibitor, Antagonist 58-64-0

(2) Tocris Compounds for MYLK3 Gene

Compound Action Cas Number
ML 9 hydrochloride Myosin light chain kinase inhibitor 105637-50-1
MLCK inhibitor peptide 18 Selective inhibitor of myosin light chain kinase 224579-74-2

(2) ApexBio Compounds for MYLK3 Gene

Compound Action Cas Number
ML-7 hydrochloride Myosin light chain kinase inhibitor 110448-33-4
Omecamtiv mecarbil Cardiac myosin activator 873697-71-3
genes like me logo Genes that share compounds with MYLK3: view

Drug Products

Transcripts for MYLK3 Gene

mRNA/cDNA for MYLK3 Gene

2 REFSEQ mRNAs :
9 NCBI additional mRNA sequence :
7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MYLK3

Alternative Splicing Database (ASD) splice patterns (SP) for MYLK3 Gene

No ASD Table

Relevant External Links for MYLK3 Gene

GeneLoc Exon Structure for
MYLK3

Expression for MYLK3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MYLK3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for MYLK3 Gene

This gene is overexpressed in Heart - Left Ventricle (x23.0) and Heart - Atrial Appendage (x19.7).

Protein differential expression in normal tissues from HIPED for MYLK3 Gene

This gene is overexpressed in Testis (22.8), Heart (15.9), Fetal heart (12.0), Liver, secretome (9.9), and Tonsil (6.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for MYLK3 Gene



Protein tissue co-expression partners for MYLK3 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MYLK3

SOURCE GeneReport for Unigene cluster for MYLK3 Gene:

Hs.130465

mRNA Expression by UniProt/SwissProt for MYLK3 Gene:

Q32MK0-MYLK3_HUMAN
Tissue specificity: Restricted to heart.

Evidence on tissue expression from TISSUES for MYLK3 Gene

  • Muscle(3.3)
  • Heart(3.3)
  • Blood(2.1)
  • Intestine(2.1)
genes like me logo Genes that share expression patterns with MYLK3: view

No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for MYLK3 Gene

Orthologs for MYLK3 Gene

This gene was present in the common ancestor of animals.

Orthologs for MYLK3 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia MYLK3 30 31
  • 99.43 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia MYLK3 30 31
  • 82.1 (n)
OneToOne
Mouse
(Mus musculus)
Mammalia Mylk3 30 17 31
  • 78.02 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Mylk3 30
  • 77.94 (n)
Dog
(Canis familiaris)
Mammalia MYLK3 30 31
  • 77.85 (n)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia MYLK3 31
  • 64 (a)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia MYLK3 31
  • 58 (a)
OneToOne
Chicken
(Gallus gallus)
Aves MYLK3 30 31
  • 57.68 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia MYLK3 31
  • 68 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia mylk3 30
  • 63.8 (n)
Zebrafish
(Danio rerio)
Actinopterygii mylk3 31
  • 41 (a)
OneToOne
Fruit Fly
(Drosophila melanogaster)
Insecta sqa 31
  • 17 (a)
OneToMany
Worm
(Caenorhabditis elegans)
Secernentea ZC373.4 31
  • 13 (a)
OneToMany
Species where no ortholog for MYLK3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for MYLK3 Gene

ENSEMBL:
Gene Tree for MYLK3 (if available)
TreeFam:
Gene Tree for MYLK3 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for MYLK3: view image

Paralogs for MYLK3 Gene

(29) SIMAP similar genes for MYLK3 Gene using alignment to 2 proteins:

  • MYLK3_HUMAN
  • L8E9T3_HUMAN
genes like me logo Genes that share paralogs with MYLK3: view

Variants for MYLK3 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MYLK3 Gene

SNP ID Clinical significance and condition Chr 16 pos Variation AA Info Type
726998 Likely Benign: not provided 46,727,242(-) G/A SYNONYMOUS_VARIANT
775374 Benign: not provided 46,737,980(-) T/A SYNONYMOUS_VARIANT,INTRON_VARIANT
rs141602742 A colorectal cancer sample p.Gly390Arg
rs28407821 - p.Val180Leu
rs9923813 - p.Ser70Thr

Additional dbSNP identifiers (rs#s) for MYLK3 Gene

Structural Variations from Database of Genomic Variants (DGV) for MYLK3 Gene

Variant ID Type Subtype PubMed ID
dgv2975n100 CNV gain 25217958
esv3571142 CNV gain 25503493
esv3638534 CNV gain 21293372
esv3638540 CNV gain 21293372
esv3638541 CNV gain 21293372
esv3892855 CNV loss 25118596
nsv1066115 CNV gain 25217958
nsv526656 CNV gain 19592680

Variation tolerance for MYLK3 Gene

Residual Variation Intolerance Score: 19% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.59; 82.57% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for MYLK3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MYLK3

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MYLK3 Gene

Disorders for MYLK3 Gene

MalaCards: The human disease database

(2) MalaCards diseases for MYLK3 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
hypoplastic right heart syndrome
  • right hypoplastic heart syndrome
dilated cardiomyopathy
  • cardiomyopathy, familial idiopathic
- elite association - COSMIC cancer census association via MalaCards
Search MYLK3 in MalaCards View complete list of genes associated with diseases
genes like me logo Genes that share disorders with MYLK3: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MYLK3 Gene

Publications for MYLK3 Gene

  1. A cardiac myosin light chain kinase regulates sarcomere assembly in the vertebrate heart. (PMID: 17885681) Seguchi O … Kitakaze M (The Journal of clinical investigation 2007) 2 3 4
  2. Mechanism of IL-1beta-induced increase in intestinal epithelial tight junction permeability. (PMID: 18390750) Al-Sadi R … Ma TY (Journal of immunology (Baltimore, Md. : 1950) 2008) 3 23
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
  4. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3
  5. Identification of MYLK3 mutations in familial dilated cardiomyopathy. (PMID: 29235529) Tobita T … Komuro I (Scientific reports 2017) 3

Products for MYLK3 Gene

  • Signalway Proteins for MYLK3

Sources for MYLK3 Gene