Aliases for MYL6 Gene
External Ids for MYL6 Gene
Previous GeneCards Identifiers for MYL6 Gene
Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain that is expressed in smooth muscle and non-muscle tissues. Genomic sequences representing several pseudogenes have been described and two transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for MYL6 Gene
MYL6 (Myosin Light Chain 6) is a Protein Coding gene. Diseases associated with MYL6 include Primary Cutaneous Amyloidosis. Among its related pathways are Oxytocin signaling pathway and Sertoli-Sertoli Cell Junction Dynamics. Gene Ontology (GO) annotations related to this gene include calcium ion binding and structural constituent of muscle. An important paralog of this gene is MYL6B.
UniProtKB/Swiss-Prot Summary for MYL6 Gene
Regulatory light chain of myosin. Does not bind calcium.
Myosins are a large family of motor proteins that share the common features of ATP hydrolysis (ATPase enzyme activity), actin binding and potential for kinetic energy transduction. Originally isolated from muscle cells, almost all eukaryotic cells are known to contain myosins.