Aliases for MYL5 Gene
Aliases for MYL5 Gene
External Ids for MYL5 Gene
- HGNC: 7586
- Entrez Gene: 4636
- Ensembl: ENSG00000215375
- OMIM: 160782
- UniProtKB: Q02045
Previous GeneCards Identifiers for MYL5 Gene
- GC04P000677
- GC04P000658
- GC04P000661
Summaries for MYL5 Gene
-
This gene encodes one of the myosin light chains, a component of the hexameric ATPase cellular motor protein myosin. Myosin is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene product, one of the regulatory light chains, is expressed in fetal muscle and in adult retina, cerebellum, and basal ganglia. [provided by RefSeq, Jul 2008]
GeneCards Summary for MYL5 Gene
MYL5 (Myosin Light Chain 5) is a Protein Coding gene. Among its related pathways are ERK Signaling and Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases. Gene Ontology (GO) annotations related to this gene include calcium ion binding and structural constituent of muscle. An important paralog of this gene is MYL7.
-
Myosins are a large family of motor proteins that share the common features of ATP hydrolysis (ATPase enzyme activity), actin binding and potential for kinetic energy transduction. Originally isolated from muscle cells, almost all eukaryotic cells are known to contain myosins.
No data available for CIViC summary , UniProtKB/Swiss-Prot , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MYL5 Gene
Genomics for MYL5 Gene
GeneHancer (GH) Regulatory Elements for MYL5 Gene
Promoters and enhancers for MYL5 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around MYL5 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the MYL5 gene promoter:
-
- ATF-2
- SRF (504 AA)
- SRF
- ATF6
- HEN1
- NF-1
- NF-1/L
- AML1a
- YY1
- POU2F1
Regulatory Element Products
Genomic Locations for MYL5 Gene
Genomic Locations for MYL5 Gene
- chr4:673,580-682,033
- (GRCh38/hg38)
- Size:
- 8,454 bases
- Orientation:
- Plus strand
- chr4:667,369-675,822
- (GRCh37/hg19)
- Size:
- 8,454 bases
- Orientation:
- Plus strand
Genomic View for MYL5 Gene
Genes around MYL5 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 4p16.3 by Entrez Gene
- 4p16.3 by HGNC
- 4p16.3 by Ensembl
MYL5 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MYL5 Gene
Proteins for MYL5 Gene
-
Protein details for MYL5 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q02045-MYL5_HUMAN
- Recommended name:
- Myosin light chain 5
- Protein Accession:
- Q02045
- Q8IXL8
Protein attributes for MYL5 Gene
- Size:
- 173 amino acids
- Molecular mass:
- 19534 Da
- Quaternary structure:
-
- Myosin is a hexamer of 2 heavy chains and 4 light chains.
- Miscellaneous:
-
- This chain binds calcium.
Protein Expression for MYL5 Gene
Post-translational modifications for MYL5 Gene
Other Protein References for MYL5 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for MYL5
-
Abcam antibodies for MYL5
- Invitrogen Antibodies for MYL5
- Search GeneTex for Antibodies for MYL5
-
Biorbyt antibodies for MYL5
-
Santa Cruz Biotechnology (SCBT) Antibodies for MYL5
Protein Products
-
OriGene Purified Proteins for MYL5
- Search Origene for MassSpec and Protein Over-expression Lysates for MYL5
- Origene Custom Protein Services for MYL5
- ProSpec Recombinant Proteins for MYL5
- antibodies-online: Search results for 9 available MYL5 Proteins ranked by validation data
- Compare Top MYL5 Proteins
-
Quality Products:
- Search GeneTex for Proteins for MYL5
-
Abcam proteins for MYL5
Assay Products
- antibodies-online: Search results for available MYL5 related products ranked by validation data
No data available for DME Specific Peptides for MYL5 Gene
Domains & Families for MYL5 Gene
Gene Families for MYL5 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for MYL5 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for MYL5 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for MYL5 Gene
Function for MYL5 Gene
Molecular function for MYL5 Gene
- GENATLAS Biochemistry:
- myosin,light polypeptide 5,regulatory
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005509 | calcium ion binding | IEA | -- |
| GO:0008307 | structural constituent of muscle | TAS | 1284596 |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for MYL5 Gene
- GenomeRNAi human phenotypes for MYL5:
-
- Dynamic nuclei (hole, folded or small irregular)
- Decreased focal adhesion (FA) area, decreased FA length, decreased FA mean intensity, increased number of small and round FAs, increased FA abundance
- Negative genetic interaction between PTTG1-/- and PTTG1+/+
- Negative genetic interaction between BLM-/- and BLM+/+
- Negative genetic interaction between PTEN-/- and PTEN+/+
- Decreased viability in esophageal squamous lineage
- Increased circadian period length
- Decreased viability
- Increased cell migration
- Decreased cell migration
- no effect
- Increased vaccinia virus (VACV) infection
- Decreased JFH-1 genotype 2a Hepatitis C virus (HCV) infection
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MYL5
-
CRISPR Products
-
OriGene CRISPR knockouts for MYL5
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MYL5
- genomics-online: gRNA clones - Search results for 31 available MYL5 gene related products
- Overview of 31 available MYL5 gene related products
- Applied Biological Materials CRISPR for MYL5
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for MYL5
- GenScript: Design CRISPR guide RNA sequences for MYL5
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MYL5
- Browse OriGene Inhibitory RNA Products For MYL5
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MYL5
- genomics-online: shRNA clones - Search results for 31 available MYL5 gene related products
- Overview of 31 available MYL5 gene related products
Clone Products
- Sino Biological Human cDNA Clone for MYL5
- VectorBuilder custom plasmid, inducible vectors for MYL5
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MYL5
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MYL5
- Applied Biological Materials Clones for MYL5
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for MYL5
No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MYL5 Gene
Localization for MYL5 Gene
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| cytoskeleton | 4 |
| mitochondrion | 2 |
| nucleus | 2 |
- Nucleoli (2)
- Nucleus (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005829 | cytosol | TAS | -- |
| GO:0005859 | muscle myosin complex | TAS | 1284596 |
| GO:0016459 | myosin complex | IEA | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for MYL5 Gene
Pathways & Interactions for MYL5 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Activation of cAMP-Dependent PKA |
.77
|
.56
|
| 2 | Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases | ||
| 3 | PAK Pathway |
.56
|
|
| 4 | Actin Nucleation by ARP-WASP Complex |
.35
|
|
| 5 | RhoGDI Pathway |
.33
|
|
Pathways by source for MYL5 Gene
2 Reactome pathways for MYL5 Gene
3 KEGG pathways for MYL5 Gene
6 GeneGo (Thomson Reuters) pathways for MYL5 Gene
16 Qiagen pathways for MYL5 Gene
Interacting Proteins for MYL5 Gene
GPS-Prot Interaction Network for MYL5
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006936 | muscle contraction | TAS | -- |
| GO:0006937 | regulation of muscle contraction | TAS | 1284596 |
No data available for SIGNOR curated interactions for MYL5 Gene
Drugs & Compounds for MYL5 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| calcium | Approved | Nutra | 0 | |||
| (R)-(+)-Blebbistatin | Pharma | non-muscle myosin II ATPases inhibitor, cell-permeable, Selective inhibitor of myosin II ATPase activity. Inactive enantiomer of (+-)-blebbistatin (Cat. No. 1760) | 0 | |||
| BTS | Pharma | Selective inhibitor of skeletal muscle myosin II ATPase activity | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| (+-)-Blebbistatin |
|
674289-55-5 |
|
|
||
| (S)-(-)-Blebbistatin |
|
856925-71-8 |
|
|
(4) Tocris Compounds for MYL5 Gene
| Compound | Action | Cas Number |
|---|---|---|
| (+-)-Blebbistatin | Selective inhibitor of myosin II ATPase activity | 674289-55-5 |
| (R)-(+)-Blebbistatin | Selective inhibitor of myosin II ATPase activity. Inactive enantiomer of (+-)-blebbistatin (Cat. No. 1760) | 1177356-70-5 |
| (S)-(-)-Blebbistatin | Selective inhibitor of myosin II ATPase activity. Active enantiomer of (+-)-blebbistatin (Cat. No. 1760) | 856925-71-8 |
| BTS | Selective inhibitor of skeletal muscle myosin II ATPase activity | 1576-37-0 |
Drug Products
Transcripts for MYL5 Gene
mRNA/cDNA for MYL5 Gene
- (5) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (50) Selected AceView cDNA sequences:
- (9) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000506838 2956 bps (uc062ufb.1)
- ENST00000505477 584 bps (uc062ufc.1)
- ENST00000503300 1780 bps (uc062ufd.1)
- ENST00000502720 551 bps (uc062ufe.1)
- ENST00000511290 781 bps (uc062uff.1)
Unigene Clusters for MYL5 Gene
- Myosin, light chain 5, regulatory:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for MYL5
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MYL5
- genomics-online: gRNA clones - Search results for 31 available MYL5 gene related products
- Overview of 31 available MYL5 gene related products
- Applied Biological Materials CRISPR for MYL5
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for MYL5
- GenScript: Design CRISPR guide RNA sequences for MYL5
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MYL5
- Browse OriGene Inhibitory RNA Products For MYL5
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MYL5
- genomics-online: shRNA clones - Search results for 31 available MYL5 gene related products
- Overview of 31 available MYL5 gene related products
Clone Products
- Sino Biological Human cDNA Clone for MYL5
- VectorBuilder custom plasmid, inducible vectors for MYL5
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MYL5
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MYL5
- Applied Biological Materials Clones for MYL5
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for MYL5 Gene
This gene is overexpressed in Heart (48.4) and Fetal heart (10.8).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for MYL5 Gene
NURSA nuclear receptor signaling pathways regulating expression of MYL5 Gene:
MYL5SOURCE GeneReport for Unigene cluster for MYL5 Gene:
Hs.410970mRNA Expression by UniProt/SwissProt for MYL5 Gene:
Q02045-MYL5_HUMAN
Tissue specificity:
Expressed in fetal skeletal muscle and retina.
Primer Products
-
OriGene qPCR primer pairs and template standards for MYL5
-
OriGene qPCR primer pairs for MYL5
- genomics-online: primer clones - Search results for 31 available MYL5 gene related products
- Overview of 31 available MYL5 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MYL5 Gene
Orthologs for MYL5 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | MYL5 34 33 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | MYL5 34 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | MYL5 34 33 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | MYL5 34 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | MYL5 34 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | CABZ01076669.1 34 |
|
ManyToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | mlc-1 35 |
|
|
|
| mlc-2 35 |
|
|
|||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.11077 34 |
|
ManyToMany | |
| CSA.10194 34 |
|
ManyToMany |
- Species where no ortholog for MYL5 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- cow (Bos Taurus)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
Evolution for MYL5 Gene
- ENSEMBL:
- Gene Tree for MYL5 (if available)
- TreeFam:
- Gene Tree for MYL5 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for MYL5: view image
Paralogs for MYL5 Gene
(15) SIMAP similar genes for MYL5 Gene using alignment to 4 proteins:
- MYL5_HUMAN
- D6RA88_HUMAN
- D6RB15_HUMAN
- D6RJ91_HUMAN
Variants for MYL5 Gene
| SNP ID | Clin | Chr 04 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000226214 | -- | 676,383(+) | C/T | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1001105378 | -- | 679,599(+) | G/A | intron_variant | |
| rs1001208988 | -- | 677,864(+) | C/G | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1001333124 | -- | 680,872(+) | T/C | intron_variant | |
| rs1001385348 | -- | 681,041(+) | G/A/T | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2759217 | CNV | loss | 17122850 |
| esv995514 | CNV | insertion | 20482838 |
| nsv10413 | CNV | gain | 18304495 |
| nsv1110773 | CNV | insertion | 24896259 |
| nsv1143073 | CNV | tandem duplication | 24896259 |
| nsv508986 | CNV | insertion | 20534489 |
| nsv593206 | CNV | loss | 21841781 |
| nsv593208 | CNV | loss | 21841781 |
| nsv822425 | CNV | loss | 20364138 |
| nsv829834 | CNV | loss | 17160897 |
| nsv950325 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
83.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.46;
71.58% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for MYL5 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MYL5
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MYL5 Gene
Disorders for MYL5 Gene
Additional Disease Information for MYL5
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for MYL5 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MYL5 Gene
Publications for MYL5 Gene
- The genomic organization of a novel regulatory myosin light chain gene (MYL5) that maps to chromosome 4p16.3 and shows different patterns of expression between primates. (PMID: 1284596) Collins C … Hayden MR (Human molecular genetics 1992) 2 3 4 58
- Human variation in alcohol response is influenced by variation in neuronal signaling genes. (PMID: 20201926) Joslyn G … White RL (Alcoholism, clinical and experimental research 2010) 3 44 58
- Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
- Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) Oláh J … Ovádi J (The Journal of biological chemistry 2011) 3 58
- Intact lipid rafts regulate HIV-1 Tat protein-induced activation of the Rho signaling and upregulation of P-glycoprotein in brain endothelial cells. (PMID: 19794400) Zhong Y … Toborek M (Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2010) 3 58
Products for MYL5 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Human Proteins and Enzymes
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for MYL5
- Search Origene for MassSpec and Protein Over-expression Lysates for MYL5
- Origene Custom Protein Services for MYL5
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MYL5
- Browse OriGene Inhibitory RNA Products For MYL5
- OriGene qPCR primer pairs and template standards for MYL5
- OriGene qPCR primer pairs for MYL5
- OriGene CRISPR knockouts for MYL5
- OriGene ORF clones in human for MYL5
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For MYL5
- GenScript: Next-day shipping of latest version cDNA ORF clones for MYL5 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for MYL5
- GenScript Custom Assay Services for MYL5
- GenScript Custom overexpressing Cell Line Services for MYL5
- GenScript: Design CRISPR guide RNA sequences for MYL5
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for MYL5
- Sino Biological Human cDNA Clone for MYL5
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for MYL5
- Novus Biologicals proteins and lysates for MYL5
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for MYL5
- Abcam proteins for MYL5
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- ProSpec Recombinant Proteins for MYL5
- VectorBuilder custom plasmid, inducible vectors for MYL5
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MYL5
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 15 available MYL5 Antibodies ranked by validation data
- Compare Top MYL5 Antibodies
- Quality Products:
- antibodies-online: Search results for available MYL5 related products ranked by validation data
- antibodies-online: Search results for 9 available MYL5 Proteins ranked by validation data
- Compare Top MYL5 Proteins
- Quality Products:
- Search GeneTex for Antibodies for MYL5
- Search GeneTex for Proteins for MYL5
- Santa Cruz Biotechnology (SCBT) Antibodies for MYL5
- Search Santa Cruz Biotechnology (SCBT) for MYL5 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for MYL5
- Horizon Cell Lines for MYL5
- genomics-online: cdna clones - Search results for 31 available MYL5 gene related products
- Overview of 31 available MYL5 gene related products
- orf clones - Search results for 31 available MYL5 gene related products
- Overview of 31 available MYL5 gene related products
- genomics-online: gRNA clones - Search results for 31 available MYL5 gene related products
- Overview of 31 available MYL5 gene related products
- genomics-online: primer clones - Search results for 31 available MYL5 gene related products
- Overview of 31 available MYL5 gene related products
- genomics-online: shRNA clones - Search results for 31 available MYL5 gene related products
- Overview of 31 available MYL5 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MYL5
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MYL5
- GeneCopoeia miRNA 3'UTR Target clone products for MYL5
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MYL5
- Biorbyt antibodies for MYL5
Sources for MYL5 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt