Aliases for MYL1 Gene
External Ids for MYL1 Gene
Previous GeneCards Identifiers for MYL1 Gene
Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain expressed in fast skeletal muscle. Two transcript variants have been identified for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for MYL1 Gene
MYL1 (Myosin Light Chain 1) is a Protein Coding gene. Diseases associated with MYL1 include Myopathy, Congenital, With Fast-Twitch Fiber Atrophy and Myopathy, Congenital. Among its related pathways are Sertoli-Sertoli Cell Junction Dynamics and Immune response CCR3 signaling in eosinophils. Gene Ontology (GO) annotations related to this gene include calcium ion binding and structural constituent of muscle. An important paralog of this gene is MYL4.
UniProtKB/Swiss-Prot Summary for MYL1 Gene
Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function.
Myosins are a large family of motor proteins that share the common features of ATP hydrolysis (ATPase enzyme activity), actin binding and potential for kinetic energy transduction. Originally isolated from muscle cells, almost all eukaryotic cells are known to contain myosins.