Aliases for MYF5 Gene
External Ids for MYF5 Gene
Previous GeneCards Identifiers for MYF5 Gene
GeneCards Summary for MYF5 Gene
MYF5 (Myogenic Factor 5) is a Protein Coding gene. Diseases associated with MYF5 include Ophthalmoplegia, External, With Rib And Vertebral Anomalies and Scoliosis. Among its related pathways are Signaling pathways regulating pluripotency of stem cells and Myogenesis. Gene Ontology (GO) annotations related to this gene include sequence-specific DNA binding and RNA polymerase II proximal promoter sequence-specific DNA binding. An important paralog of this gene is MYOD1.
UniProtKB/Swiss-Prot Summary for MYF5 Gene
Transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation (PubMed:29887215). Together with MYOG and MYOD1, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein.