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Aliases for MXRA7 Gene

Aliases for MXRA7 Gene

  • Matrix Remodeling Associated 7 2 3 5
  • Matrix-Remodelling Associated 7 2 3
  • Transmembrane Anchor Protein 1 3 4
  • TMAP1 3 4
  • Matrix-Remodeling-Associated Protein 7 3
  • HBV PreS1-Transactivated Protein 1 3
  • PS1TP1 3

External Ids for MXRA7 Gene

Previous GeneCards Identifiers for MXRA7 Gene

  • GC00U990745
  • GC17M072187
  • GC17M074671
  • GC17M070099

Summaries for MXRA7 Gene

GeneCards Summary for MXRA7 Gene

MXRA7 (Matrix Remodeling Associated 7) is a Protein Coding gene.

Additional gene information for MXRA7 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MXRA7 Gene

Genomics for MXRA7 Gene

GeneHancer (GH) Regulatory Elements for MXRA7 Gene

Promoters and enhancers for MXRA7 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17I076707 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 598.5 +1.3 1308 4.6 HDGF PKNOX1 ATF1 ZFP64 ARID4B SIN3A ZNF48 ZNF121 GLIS2 ZNF143 MXRA7 ENSG00000277382 RNU6-227P PRCD CYGB GC17M076710 RNY4P36
GH17I076686 Enhancer 1.4 Ensembl ENCODE dbSUPER 70.3 +22.8 22825 3.3 PKNOX1 MLX ARID4B FEZF1 DMAP1 ZNF48 SLC30A9 GLIS2 ATF7 FOS GC17M076685 MXRA7 JMJD6 RNU6-227P METTL23 PRCD CYGB UBE2O RNU6-97P AANAT
GH17I076694 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 51.8 +12.0 12001 8.4 HDGF PKNOX1 FOXA2 MLX ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF2 UNK MXRA7 SRSF2 ENSG00000266980 METTL23 MFSD11 ENSG00000267546 SRP68 ENSG00000267342 RNU6-227P
GH17I076681 Enhancer 1.3 Ensembl ENCODE dbSUPER 62.2 +28.2 28182 3.7 HDGF RB1 ARID4B SIN3A ZNF48 RAD21 ARID2 ZNF143 RCOR1 RUNX3 MXRA7 RNU6-227P METTL23 JMJD6 GC17M076685 GC17M076671
GH17I076733 Promoter/Enhancer 3 UCNEbase EPDnew Ensembl ENCODE dbSUPER 24.5 -26.2 -26243 7.8 CLOCK ZFP64 FEZF1 DMAP1 IRF4 YY1 SLC30A9 E2F8 ZNF143 ZNF548 SRSF2 MFSD11 MIR636 UNK ENSG00000267342 TRIM65 ENSG00000266980 SEPT9 ENSG00000267546 METTL23
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MXRA7 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the MXRA7 gene promoter:

Genomic Locations for MXRA7 Gene

Genomic Locations for MXRA7 Gene
38,466 bases
Minus strand

Genomic View for MXRA7 Gene

Genes around MXRA7 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MXRA7 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MXRA7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MXRA7 Gene

Proteins for MXRA7 Gene

  • Protein details for MXRA7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Matrix-remodeling-associated protein 7
    Protein Accession:
    Secondary Accessions:
    • Q0P5W3

    Protein attributes for MXRA7 Gene

    204 amino acids
    Molecular mass:
    21466 Da
    Quaternary structure:
    No Data Available
    • Sequence=AW888225; Type=Frameshift; Positions=Several; Evidence={ECO:0000305};

    Alternative splice isoforms for MXRA7 Gene


neXtProt entry for MXRA7 Gene

Post-translational modifications for MXRA7 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for MXRA7 Gene

Domains & Families for MXRA7 Gene

Gene Families for MXRA7 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Predicted secreted proteins

Protein Domains for MXRA7 Gene


Suggested Antigen Peptide Sequences for MXRA7 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MXRA7: view

No data available for UniProtKB/Swiss-Prot for MXRA7 Gene

Function for MXRA7 Gene

Phenotypes From GWAS Catalog for MXRA7 Gene

Phenotypes for MXRA7 Gene

genes like me logo Genes that share phenotypes with MXRA7: view

Animal Model Products

  • Taconic Biosciences Mouse Models for MXRA7

CRISPR Products

miRNA for MXRA7 Gene

miRTarBase miRNAs that target MXRA7

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MXRA7 Gene

Localization for MXRA7 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MXRA7 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MXRA7 gene
Compartment Confidence
extracellular 5
endoplasmic reticulum 3
nucleus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Endoplasmic reticulum (2)
  • Nucleus (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for MXRA7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
GO:0031012 extracellular matrix IDA 27559042
genes like me logo Genes that share ontologies with MXRA7: view

Pathways & Interactions for MXRA7 Gene

SuperPathways for MXRA7 Gene

No Data Available

Interacting Proteins for MXRA7 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: P84157-MXRA7_HUMAN ENSP00000348050 for MXRA7 Gene via IID STRING

Gene Ontology (GO) - Biological Process for MXRA7 Gene


No data available for Pathways by source and SIGNOR curated interactions for MXRA7 Gene

Drugs & Compounds for MXRA7 Gene

No Compound Related Data Available

Transcripts for MXRA7 Gene

Unigene Clusters for MXRA7 Gene

Matrix-remodelling associated 7:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MXRA7 Gene

No ASD Table

Relevant External Links for MXRA7 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MXRA7 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MXRA7 Gene

Protein differential expression in normal tissues from HIPED for MXRA7 Gene

This gene is overexpressed in Bone (10.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for MXRA7 Gene

Protein tissue co-expression partners for MXRA7 Gene

NURSA nuclear receptor signaling pathways regulating expression of MXRA7 Gene:


SOURCE GeneReport for Unigene cluster for MXRA7 Gene:


Evidence on tissue expression from TISSUES for MXRA7 Gene

  • Skin(4.4)
  • Eye(3.5)
  • Nervous system(3.3)
  • Heart(2.2)
  • Muscle(2.2)
  • Pancreas(2.1)
  • Adrenal gland(2)
  • Thyroid gland(2)
genes like me logo Genes that share expression patterns with MXRA7: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for MXRA7 Gene

Orthologs for MXRA7 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MXRA7 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia MXRA7 34 33
  • 99.67 (n)
(Mus musculus)
Mammalia Mxra7 34
  • 63 (a)
(Gallus gallus)
Aves MXRA7 34
  • 45 (a)
(Danio rerio)
Actinopterygii mxra7 34
  • 32 (a)
Species where no ortholog for MXRA7 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MXRA7 Gene

Gene Tree for MXRA7 (if available)
Gene Tree for MXRA7 (if available)

Paralogs for MXRA7 Gene

No data available for Paralogs for MXRA7 Gene

Variants for MXRA7 Gene

Sequence variations from dbSNP and Humsavar for MXRA7 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1000026299 -- 76,683,916(-) G/A coding_sequence_variant, intron_variant, missense_variant, non_coding_transcript_variant
rs1000028392 -- 76,674,393(-) G/A 3_prime_UTR_variant, genic_downstream_transcript_variant
rs1000087203 -- 76,688,961(-) C/T genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1000098488 -- 76,674,235(-) C/G 3_prime_UTR_variant, genic_downstream_transcript_variant
rs1000120208 -- 76,710,735(-) G/A coding_sequence_variant, genic_upstream_transcript_variant, missense_variant, upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MXRA7 Gene

Variant ID Type Subtype PubMed ID
esv2190268 CNV deletion 18987734
esv2426649 CNV deletion 19546169
esv2716258 CNV deletion 23290073
esv2716259 CNV deletion 23290073
esv2716260 CNV deletion 23290073
esv2716261 CNV deletion 23290073
esv28006 CNV gain 19812545
nsv111859 CNV insertion 16902084
nsv1121528 CNV deletion 24896259
nsv1134678 CNV deletion 24896259
nsv828109 CNV gain 20364138
nsv960533 CNV duplication 23825009

Variation tolerance for MXRA7 Gene

Gene Damage Index Score: 12.69; 94.62% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for MXRA7 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MXRA7 Gene

Disorders for MXRA7 Gene

Additional Disease Information for MXRA7

No disorders were found for MXRA7 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MXRA7 Gene

Publications for MXRA7 Gene

  1. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody MC … Nusbaum C (Nature 2006) 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  4. Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation. (PMID: 27559042) Barallobre-Barreiro J … Mayr M (Circulation 2016) 3 58
  5. Genetic loci for retinal arteriolar microcirculation. (PMID: 23776548) Sim X … Wong TY (PloS one 2013) 3 58

Products for MXRA7 Gene

Sources for MXRA7 Gene

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