This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes lo... See more...

Aliases for MX1 Gene

Aliases for MX1 Gene

  • MX Dynamin Like GTPase 1 2 3 5
  • IFI-78K 2 3 4
  • Interferon-Regulated Resistance GTP-Binding Protein MxA 3 4
  • Interferon-Induced GTP-Binding Protein Mx1 3 4
  • Interferon-Inducible Protein P78 2 3
  • Interferon-Induced Protein P78 3 4
  • Myxoma Resistance Protein 1 3 4
  • LncMX1-215 2 3
  • MxA 2 3
  • Myxovirus (Influenza) Resistance 1, Homolog Of Murine (Interferon-Inducible Protein P78) 2
  • Myxovirus (Influenza Virus) Resistance 1, Interferon-Inducible Protein P78 (Mouse) 2
  • Myxovirus (Influenza Virus) Resistance 1, Interferon-Inducible Protein P78 3
  • Myxovirus Resistance Protein 1 4
  • IFI78 3
  • MX1 5
  • MX 3

External Ids for MX1 Gene

Previous GeneCards Identifiers for MX1 Gene

  • GC21P039372
  • GC21P041713
  • GC21P041718
  • GC21P041720
  • GC21P042792
  • GC21P028262

Summaries for MX1 Gene

Entrez Gene Summary for MX1 Gene

  • This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

GeneCards Summary for MX1 Gene

MX1 (MX Dynamin Like GTPase 1) is a Protein Coding gene. Diseases associated with MX1 include Influenza and Viral Encephalitis. Among its related pathways are Interferon gamma signaling and PI3K-Akt signaling pathway. Gene Ontology (GO) annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is MX2.

UniProtKB/Swiss-Prot Summary for MX1 Gene

  • Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus (IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs.

Gene Wiki entry for MX1 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MX1 Gene

Genomics for MX1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MX1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH21J041419 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE CraniofacialAtlas 623.7 +0.5 520 2.4 PRDM10 ZNF629 IKZF1 PRDM1 RBFOX2 PATZ1 IRF2 SP1 ZNF600 ZNF341 MX1 lnc-MX1-4 piR-31432-431 piR-40154-107 piR-52261-167 piR-46662-418 piR-53431-435 TMPRSS2
GH21J041359 Promoter/Enhancer 1.7 EPDnew Ensembl ENCODE dbSUPER 600.2 -58.2 -58200 5.7 HNRNPL CTCF REST POLR2A BACH1 LARP7 STAT3 SMAD5 TCF12 IKZF2 MX2 lnc-FAM3B-3 MX1 FAM3B piR-38351-289
GH21J041425 Promoter/Enhancer 1.4 EPDnew Ensembl ENCODE 626.9 +6.2 6197 2.2 REST POLR2A BACH1 ZNF143 RBFOX2 SMAD5 SP1 TRIM22 EZH2 YY1 MX1 MX2 piR-38537-031 lnc-MX1-4 ENSG00000228318 TMPRSS2
GH21J041365 Promoter/Enhancer 1.6 Ensembl ENCODE CraniofacialAtlas dbSUPER 11 -51.4 -51437 5.8 CREB1 GATAD2A CTCF ZBTB33 RFX1 RCOR2 POLR2A BACH1 JUND LARP7 MX2 MX1 ENSG00000228318 FAM3B lnc-FAM3B-3 piR-38351-289
GH21J041396 Enhancer 0.8 Ensembl ENCODE 18.3 -23.7 -23704 4.4 CREB1 ATF7 FOXA1 ZNF512B CEBPB ZKSCAN1 CTBP1 KLF4 ZNF217 ATF2 MX1 MX2 ENSG00000228318 piR-38351-289 lnc-MX1-4
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MX1 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for MX1

Top Transcription factor binding sites by QIAGEN in the MX1 gene promoter:
  • AP-1
  • CREB
  • deltaCREB
  • STAT5A

Genomic Locations for MX1 Gene

Genomic Locations for MX1 Gene
chr21:41,420,304-41,459,214
(GRCh38/hg38)
Size:
38,911 bases
Orientation:
Plus strand
chr21:42,792,231-42,831,141
(GRCh37/hg19)
Size:
38,911 bases
Orientation:
Plus strand

Genomic View for MX1 Gene

Genes around MX1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MX1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MX1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MX1 Gene

Proteins for MX1 Gene

  • Protein details for MX1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P20591-MX1_HUMAN
    Recommended name:
    Interferon-induced GTP-binding protein Mx1
    Protein Accession:
    P20591
    Secondary Accessions:
    • B2RDA5
    • B3KU10
    • C9IYV7
    • C9J8D6
    • C9JN19
    • C9JN88
    • C9JUL1
    • C9JZS6
    • D3DSI8
    • Q86YP5
    • Q96CI3

    Protein attributes for MX1 Gene

    Size:
    662 amino acids
    Molecular mass:
    75520 Da
    Quaternary structure:
    • Homotetramer. Oligomerizes into multimeric filamentous or ring-like structures by virtue of its stalk domain. Oligomerization is critical for GTPase activity, protein stability, and recognition of viral target structures. Interacts with TRPC1, TRPC3, TRPC4, TRPC5, TRPC6 and TRPC7. Interacts with HSPA5. Interacts with DDX39A and DDX39B. Interacts with TUBB/TUBB5 (By similarity). The GTP-bound form interacts (via C-terminus) with THOV P5 protein. The GTP-bound form interacts with LACV protein N. Interacts with CCHFV protein N.

    Three dimensional structures from OCA and Proteopedia for MX1 Gene

    Alternative splice isoforms for MX1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MX1 Gene

Post-translational modifications for MX1 Gene

No data available for DME Specific Peptides for MX1 Gene

Domains & Families for MX1 Gene

Gene Families for MX1 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for MX1 Gene

Suggested Antigen Peptide Sequences for MX1 Gene

GenScript: Design optimal peptide antigens:
  • Myxovirus resistance protein 1 (MX1_HUMAN)
  • MX1 protein (Q96CI3_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P20591

UniProtKB/Swiss-Prot:

MX1_HUMAN :
  • The C-terminal GTPase effector domain (GED) is involved in oligomerization and viral target recognition.
  • Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
Domain:
  • The C-terminal GTPase effector domain (GED) is involved in oligomerization and viral target recognition.
  • The middle domain mediates self-assembly and oligomerization.
Family:
  • Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
genes like me logo Genes that share domains with MX1: view

Function for MX1 Gene

Molecular function for MX1 Gene

UniProtKB/Swiss-Prot Function:
Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus (IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs.
UniProtKB/Swiss-Prot Induction:
By type I and type III interferons. Isoform 2 is induced by HSV-1.
GENATLAS Biochemistry:
myxovirus (influenza) resistance 1;human murine MX equivalent

Phenotypes From GWAS Catalog for MX1 Gene

Gene Ontology (GO) - Molecular Function for MX1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0003924 GTPase activity IBA 21873635
GO:0005515 protein binding IPI 15047845
GO:0005525 GTP binding TAS,IEA --
GO:0008017 microtubule binding IBA 21873635
genes like me logo Genes that share ontologies with MX1: view
genes like me logo Genes that share phenotypes with MX1: view

Animal Model Products

CRISPR Products

miRNA for MX1 Gene

miRTarBase miRNAs that target MX1

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MX1

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MX1 Gene

Localization for MX1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MX1 Gene

Cytoplasm. Endoplasmic reticulum membrane. Peripheral membrane protein. Cytoplasmic side. Cytoplasm, perinuclear region. Note=Binds preferentially to negatively charged phospholipids (PubMed:21900240). Colocalizes with CCHFV protein N in the perinuclear region (PubMed:15047845). {ECO:0000269 PubMed:15047845, ECO:0000269 PubMed:21900240}.
[Isoform 2]: Cytoplasm. Nucleus. Note=Translocates into the nuclei of HSV-1 infected cells (PubMed:20603636). {ECO:0000269 PubMed:20603636}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MX1 gene
Compartment Confidence
nucleus 5
cytosol 5
plasma membrane 4
cytoskeleton 4
mitochondrion 4
endoplasmic reticulum 4
extracellular 2
endosome 2
lysosome 2
golgi apparatus 2
peroxisome 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (3)
  • Nuclear membrane (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for MX1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA 21873635
GO:0005737 cytoplasm IBA,IDA 21859714
GO:0005783 endoplasmic reticulum IEA --
GO:0005789 endoplasmic reticulum membrane IEA --
GO:0005829 cytosol TAS --
genes like me logo Genes that share ontologies with MX1: view

Pathways & Interactions for MX1 Gene

genes like me logo Genes that share pathways with MX1: view

SIGNOR curated interactions for MX1 Gene

Is activated by:

Gene Ontology (GO) - Biological Process for MX1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000266 mitochondrial fission IBA 21873635
GO:0002376 immune system process IEA --
GO:0003374 dynamin family protein polymerization involved in mitochondrial fission IBA 21873635
GO:0006915 apoptotic process TAS 9389754
GO:0006952 defense response TAS 2154602
genes like me logo Genes that share ontologies with MX1: view

Drugs & Compounds for MX1 Gene

(9) Drugs for MX1 Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials

(12) Additional Compounds for MX1 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with MX1: view

Transcripts for MX1 Gene

mRNA/cDNA for MX1 Gene

4 REFSEQ mRNAs :
15 NCBI additional mRNA sequence :
18 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MX1

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MX1 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c ^ 5a · 5b · 5c ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15a ·
SP1: - -
SP2:
SP3: - -
SP4:
SP5: -
SP6: - - - - - -
SP7:
SP8:
SP9:
SP10: -
SP11:
SP12: -
SP13:

ExUns: 15b ^ 16 ^ 17 ^ 18
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:

Relevant External Links for MX1 Gene

GeneLoc Exon Structure for
MX1

Expression for MX1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MX1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for MX1 Gene

This gene is overexpressed in Nasal epithelium (14.7), Lymph node (12.6), and Stomach (9.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for MX1 Gene



Protein tissue co-expression partners for MX1 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MX1

SOURCE GeneReport for Unigene cluster for MX1 Gene:

Hs.517307

Evidence on tissue expression from TISSUES for MX1 Gene

  • Nervous system(4.1)
  • Blood(3.6)
  • Lung(3.6)
  • Spleen(3.6)
  • Lymph node(3.3)
  • Bone marrow(3.2)
  • Liver(3.1)
  • Intestine(3.1)
  • Kidney(3.1)
  • Heart(3)
  • Muscle(2.9)
  • Skin(2.9)
  • Stomach(2.6)
  • Thyroid gland(2.4)
  • Eye(2.4)
  • Pancreas(2.3)
  • Bone(2.3)
genes like me logo Genes that share expression patterns with MX1: view

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for MX1 Gene

Orthologs for MX1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for MX1 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia MX1 30 31
  • 98.89 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia MX1 30 31
  • 80.2 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia MX1 30 31
  • 80.11 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Mx2 30
  • 76.94 (n)
Mouse
(Mus musculus)
Mammalia Mx2 31
  • 75 (a)
OneToMany
Mx1 31
  • 69 (a)
OneToMany
Platypus
(Ornithorhynchus anatinus)
Mammalia -- 31
  • 60 (a)
ManyToMany
-- 31
  • 55 (a)
ManyToMany
Oppossum
(Monodelphis domestica)
Mammalia -- 31
  • 24 (a)
ManyToMany
Chicken
(Gallus gallus)
Aves MX 31
  • 44 (a)
OneToMany
Lizard
(Anolis carolinensis)
Reptilia -- 31
  • 55 (a)
ManyToMany
-- 31
  • 52 (a)
ManyToMany
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia mx2 30
  • 64.2 (n)
Zebrafish
(Danio rerio)
Actinopterygii mxa 30 31
  • 58.39 (n)
ManyToMany
mxe 31
  • 53 (a)
ManyToMany
mxb 31 31
  • 52 (a)
ManyToMany
mxc 31
  • 50 (a)
ManyToMany
mxg 31
  • 44 (a)
ManyToMany
mxd 31
  • 43 (a)
ManyToMany
si:dkeyp-110c12.3 31
  • 42 (a)
ManyToMany
mxf 31
  • 41 (a)
ManyToMany
Rainbow Trout
(Oncorhynchus mykiss)
Actinopterygii Omy.11791 30
Fruit Fly
(Drosophila melanogaster)
Insecta shi 31
  • 18 (a)
OneToMany
Worm
(Caenorhabditis elegans)
Secernentea dyn-1 31
  • 21 (a)
OneToMany
Baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes VPS1 31
  • 26 (a)
OneToMany
Thale Cress
(Arabidopsis thaliana)
eudicotyledons DRP4C 30
  • 44.52 (n)
Rice
(Oryza sativa)
Liliopsida Os04g0129900 30
  • 47.85 (n)
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 20 (a)
OneToMany
Species where no ortholog for MX1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for MX1 Gene

ENSEMBL:
Gene Tree for MX1 (if available)
TreeFam:
Gene Tree for MX1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for MX1: view image

Paralogs for MX1 Gene

Paralogs for MX1 Gene

(3) SIMAP similar genes for MX1 Gene using alignment to 8 proteins:

  • MX1_HUMAN
  • F8W8T1_HUMAN
  • H9KVC3_HUMAN
  • H9KVC4_HUMAN
  • H9KVC7_HUMAN
  • H9KVC9_HUMAN
  • H9KVD0_HUMAN
  • H9KVD3_HUMAN
genes like me logo Genes that share paralogs with MX1: view

Variants for MX1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MX1 Gene

SNP ID Clinical significance and condition Chr 21 pos Variation AA Info Type
711249 Benign: not provided 41,443,804(+) G/A MISSENSE_VARIANT
737180 Likely Benign: not provided 41,443,800(+) G/A SYNONYMOUS_VARIANT
778182 Benign: not provided 41,452,803(+) C/T SYNONYMOUS_VARIANT,INTRON_VARIANT
778908 Benign: not provided 41,437,118(+) G/A SYNONYMOUS_VARIANT
784413 Benign: not provided 41,432,184(+) C/G INTRON_VARIANT

Additional dbSNP identifiers (rs#s) for MX1 Gene

Structural Variations from Database of Genomic Variants (DGV) for MX1 Gene

Variant ID Type Subtype PubMed ID
esv1009381 CNV deletion 20482838
esv3647060 CNV gain 21293372
esv3647063 CNV gain 21293372
esv3647064 CNV gain 21293372
esv3893413 CNV gain 25118596
nsv1057981 CNV loss 25217958
nsv459261 CNV loss 19166990
nsv587496 CNV loss 21841781
nsv834102 CNV loss 17160897

Variation tolerance for MX1 Gene

Residual Variation Intolerance Score: 20.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 11.09; 92.22% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for MX1 Gene

Human Gene Mutation Database (HGMD)
MX1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
MX1

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MX1 Gene

Disorders for MX1 Gene

MalaCards: The human disease database

(39) MalaCards diseases for MX1 Gene - From: DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
influenza
  • flu
viral encephalitis
  • epidemic encephalitis
lichen planus
  • lichen ruber planus
subacute sclerosing panencephalitis
  • sspe
hepatitis c
  • chronic hepatitis c
- elite association - COSMIC cancer census association via MalaCards
Search MX1 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for MX1

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with MX1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MX1 Gene

Publications for MX1 Gene

  1. Interferon-induced Mx proteins in antiviral host defense. (PMID: 17570575) Haller O … Kochs G (Biochimie 2007) 2 3 23
  2. [Genetic polymorphisms of MxA protein and eIF-2a-reg2 and their responses to interferon treatment in patients with chronic hepatitis B]. (PMID: 17407708) Huang YX … Ma B (Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 2007) 3 23 41
  3. Pharmacogenetics of MXA SNPs in interferon-beta treated multiple sclerosis patients. (PMID: 17126411) Weinstock-Guttman B … Ramanathan M (Journal of neuroimmunology 2007) 3 23 41
  4. Influences of MxA gene -88 G/T and IFN-gamma +874 A/T on the natural history of hepatitis B virus infection in an endemic area. (PMID: 17845304) Peng XM … Gao ZL (International journal of immunogenetics 2007) 3 23 41
  5. Association of SARS susceptibility with single nucleic acid polymorphisms of OAS1 and MxA genes: a case-control study. (PMID: 16824203) He J … Cao W (BMC infectious diseases 2006) 3 23 41

Products for MX1 Gene

  • Signalway ELISA kits for MX1
  • Signalway Proteins for MX1

Sources for MX1 Gene