Free for academic non-profit institutions. Other users need a Commercial license
The protein encoded by this gene is a component of the ESCRT-I complex, a heterotetramer, which mediates the sorting of ubiquitinated cargo protein from the plasma membrane to the endosomal vesicle. ESCRT-I complex plays an essential role in HIV budding and endosomal protein sorting. Depletion and overexpression of this and related protein (MVB12A) inhibit HIV-1 infectivity and... See more...
Aliases for MVB12B Gene
Aliases for MVB12B Gene
External Ids for MVB12B Gene
- HGNC: 23368
- NCBI Entrez Gene: 89853
- Ensembl: ENSG00000196814
- UniProtKB/Swiss-Prot: Q9H7P6
Previous HGNC Symbols for MVB12B Gene
- C9orf28
- FAM125B
Previous GeneCards Identifiers for MVB12B Gene
- GC09P129091
Summaries for MVB12B Gene
-
The protein encoded by this gene is a component of the ESCRT-I complex, a heterotetramer, which mediates the sorting of ubiquitinated cargo protein from the plasma membrane to the endosomal vesicle. ESCRT-I complex plays an essential role in HIV budding and endosomal protein sorting. Depletion and overexpression of this and related protein (MVB12A) inhibit HIV-1 infectivity and induce unusual viral assembly defects, indicating a role for MVB12 subunits in regulating ESCRT-mediated virus budding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
GeneCards Summary for MVB12B Gene
MVB12B (Multivesicular Body Subunit 12B) is a Protein Coding gene. Diseases associated with MVB12B include Glaucoma, Primary Open Angle. Among its related pathways are Endocytosis. Gene Ontology (GO) annotations related to this gene include lipid binding and ubiquitin binding.
UniProtKB/Swiss-Prot Summary for MVB12B Gene
-
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies.
Additional gene information for MVB12B Gene
- HGNC (23368)
- NCBI Entrez Gene (89853)
- Ensembl (ENSG00000196814)
- UniProtKB/Swiss-Prot (Q9H7P6)
- Open Targets Platform(ENSG00000196814)
- Search for MVB12B at DataMed
- Search for MVB12B at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MVB12B Gene
Genomics for MVB12B Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for MVB12B Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around MVB12B on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for MVB12B
Genomic Locations for MVB12B Gene
Latest Assembly
- chr9:126,326,829-126,507,041
- (GRCh38/hg38)
- Size:
- 180,213 bases
- Orientation:
- Plus strand
Previous Assembly
- chr9:129,089,108-129,269,319
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 180,212 bases
- Orientation:
- Plus strand
- chr9:129,089,128-129,269,320
- (GRCh37/hg19 by Ensembl)
- Size:
- 180,193 bases
- Orientation:
- Plus strand
Genomic View for MVB12B Gene
Genes around MVB12B on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 9q33.3 by HGNC
- 9q33.3 by Entrez Gene
- 9q33.3 by Ensembl
MVB12B Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MVB12B Gene
Proteins for MVB12B Gene
-
Protein details for MVB12B Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9H7P6-MB12B_HUMAN
- Recommended name:
- Multivesicular body subunit 12B
- Protein Accession:
- Q9H7P6
- Q8N6S7
Protein attributes for MVB12B Gene
- Size:
- 319 amino acids
- Molecular mass:
- 35620 Da
- Quaternary structure:
-
- Component of the ESCRT-I complex (endosomal sorting complex required for transport I) which consists of TSG101, VPS28, a VPS37 protein (VPS37A to -D) and MVB12A or MVB12B in a 1:1:1:1 stoichiometry. Interacts with TSG101; the association appears to be mediated by the TSG101-VPS37 binary subcomplex. Interacts with VPS28. Interacts with VPS37B; the association appears to be mediated by the TSG101-VPS37 binary subcomplex. Interacts with VPS37C; the association appears to be mediated by the TSG101-VPS37 binary subcomplex.
- SequenceCaution:
-
- Sequence=BAB15722.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for MVB12B Gene
Post-translational modifications for MVB12B Gene
Other Protein References for MVB12B Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
-
Custom Antibody ServicesOriGene Antibodies for MVB12B
- Novus Biologicals Antibodies for MVB12B
- Invitrogen Antibodies for MVB12B (AFLGC-MVB12B)
- antibodies-online: Show 5 available MVB12B Antibodies ranked by validation data
- Compare Top MVB12B Antibodies
-
Quality Products:
Protein products for research
- Search Origene for MassSpec and Protein Over-expression Lysates for MVB12B
- Origene Custom Protein Services for MVB12B
- antibodies-online: Show 4 available MVB12B Proteins ranked by validation data
- Compare Top MVB12B Proteins
-
Quality Products:
Assay products for research
No data available for DME Specific Peptides for MVB12B Gene
Domains & Families for MVB12B Gene
Gene Families for MVB12B Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Suggested Antigen Peptide Sequences for MVB12B Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ55114 (B7Z4X0_HUMAN)
- Protein FAM125B (F125B_HUMAN)
- FLJ00001 protein (Q9NXY4_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9H7P6- Family:
-
- Belongs to the MVB12 family.
Function for MVB12B Gene
Molecular function for MVB12B Gene
- UniProtKB/Swiss-Prot Function:
- Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies.
Phenotypes From GWAS Catalog for MVB12B Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 20654576 |
| GO:0008289 | lipid binding | IMP | 22232651 |
| GO:0043130 | NOT ubiquitin binding | IDA | 20654576 |
Phenotypes for MVB12B Gene
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for MVB12B - Starting at $85 >
- * MVB12B CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for MVB12B
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MVB12B
-
Santa Cruz Biotechnology (SCBT) CRISPR for MVB12B
miRNA for MVB12B Gene
- miRTarBase miRNAs that target MVB12B
-
- mmu-miR-223-3p (MIRT009672)
- mmu-miR-149-5p (MIRT014548)
- hsa-miR-877-3p (MIRT036903)
- mmu-miR-3971 (MIRT600910)
- mmu-miR-544-5p (MIRT600911)
- hsa-miR-2355-3p (MIRT628701)
- hsa-miR-676-3p (MIRT628702)
- hsa-miR-5589-3p (MIRT628703)
- hsa-miR-6715b-5p (MIRT628704)
- hsa-miR-4269 (MIRT628705)
- hsa-miR-5582-5p (MIRT628706)
- hsa-miR-6768-5p (MIRT628707)
- hsa-miR-8485 (MIRT628708)
- hsa-miR-6852-3p (MIRT630802)
- hsa-miR-3909 (MIRT630803)
- hsa-miR-4330 (MIRT646325)
- hsa-miR-6862-3p (MIRT646326)
- hsa-miR-6784-3p (MIRT646327)
- hsa-miR-1224-3p (MIRT646328)
- hsa-miR-500b-3p (MIRT646329)
- hsa-miR-6800-3p (MIRT646330)
- hsa-miR-4789-5p (MIRT667327)
- hsa-miR-3941 (MIRT667328)
- hsa-miR-603 (MIRT667329)
- hsa-miR-362-3p (MIRT667330)
- hsa-miR-329-3p (MIRT667331)
- hsa-miR-4789-3p (MIRT707335)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MVB12B
- Browse OriGene Inhibitory RNA Products For MVB12B
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MVB12B
Clone products for research
- Applied Biological Materials (abm): Clones for MVB12B - Starting at $45 >
- * MVB12B as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for MVB12B
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MVB12B
Cell Lines for research
-
Horizon Cell Lines for MVB12B
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MVB12B Gene
Localization for MVB12B Gene
Subcellular locations from UniProtKB/Swiss-Prot for MVB12B Gene
- Endosome. Late endosome membrane. Peripheral membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| nucleus | 5 |
| endosome | 5 |
| cytosol | 5 |
| extracellular | 4 |
| cytoskeleton | 1 |
| lysosome | 1 |
| mitochondrion | 0 |
- Golgi apparatus (2)
- Vesicles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000813 | ESCRT I complex | IEA,IDA | 18005716 |
| GO:0005634 | nucleus | IDA | 22232651 |
| GO:0005768 | endosome | IEA | -- |
| GO:0005769 | early endosome | IDA | 22232651 |
| GO:0005770 | late endosome | IBA,IDA | 22232651 |
Pathways & Interactions for MVB12B Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Endocytosis | ||
Pathways by source for MVB12B Gene
1 KEGG pathway for MVB12B Gene
Interacting Proteins for MVB12B Gene
Selected Interacting proteins:
Q9H7P6-MB12B_HUMAN
ENSP00000354772
for MVB12B Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for MVB12B
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0015031 | protein transport | IEA | -- |
| GO:0016197 | endosomal transport | TAS | -- |
| GO:0019058 | viral life cycle | TAS | -- |
| GO:0019075 | virus maturation | IBA,IMP | 18005716 |
| GO:0042058 | regulation of epidermal growth factor receptor signaling pathway | IBA,IMP | 20654576 |
No data available for SIGNOR curated interactions for MVB12B Gene
Transcripts for MVB12B Gene
mRNA/cDNA for MVB12B Gene
- 2 REFSEQ mRNAs :
- 13 NCBI additional mRNA sequence :
- 6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000361171 4838 nts (view in UCSC)
- ENST00000402437 770 nts (view in UCSC)
- ENST00000470567 421 nts (view in UCSC)
- ENST00000485886 4537 nts (view in UCSC)
- ENST00000489570 479 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for MVB12B - Starting at $85 >
- * MVB12B CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for MVB12B
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MVB12B
-
Santa Cruz Biotechnology (SCBT) CRISPR for MVB12B
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MVB12B
- Browse OriGene Inhibitory RNA Products For MVB12B
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MVB12B
Clone products for research
- Applied Biological Materials (abm): Clones for MVB12B - Starting at $45 >
- * MVB12B as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for MVB12B
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MVB12B
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13a | · | 13b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||||||||||||
| SP7: |
Relevant External Links for MVB12B Gene
- GeneLoc Exon Structure for
- MVB12B
Expression for MVB12B Gene
mRNA differential expression in normal tissues according to GTEx for MVB12B Gene
This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x8.1) and Brain - Substantia nigra (x4.0).
This gene is overexpressed in Serum (52.5).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for MVB12B Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MVB12B
SOURCE GeneReport for Unigene cluster for MVB12B Gene:
Hs.162659Evidence on tissue expression from TISSUES for MVB12B Gene
- Nervous system(4.9)
- Spleen(4.2)
Primer products for research
-
OriGene qPCR primer pairs for MVB12B
-
OriGene qPCR primer pairs and template standards for MVB12B
Gene Expression Assays for research
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for MVB12B Gene
Orthologs for MVB12B Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | MVB12B 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | MVB12B 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | MVB12B 31 |
|
OneToOne | |
| FAM125B 30 |
|
||||
| Cow (Bos Taurus) |
Mammalia | MVB12B 30 |
|
||
| Rat (Rattus norvegicus) |
Mammalia | Mvb12b 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Mvb12b 30 17 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | MVB12B 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | FAM125B 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | MVB12B 31 |
|
OneToOne | |
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.32390 30 |
|
||
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | Str.19086 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | mvb12ba 30 31 |
|
OneToMany | |
| mvb12bb 31 |
|
OneToMany | |||
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG7192 31 |
|
OneToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | mvb-12 30 31 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.10662 31 |
|
OneToMany |
- Species where no ortholog for MVB12B was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for MVB12B Gene
- ENSEMBL:
- Gene Tree for MVB12B (if available)
- TreeFam:
- Gene Tree for MVB12B (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for MVB12B: view image
Paralogs for MVB12B Gene
(2) SIMAP similar genes for MVB12B Gene using alignment to 4 proteins:
- MB12B_HUMAN
- B7Z4X0_HUMAN
- F8W922_HUMAN
- G8JLL7_HUMAN
No data available for Paralogs for MVB12B Gene
Variants for MVB12B Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MVB12B Gene
| SNP ID | Clinical significance and condition | Chr 09 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs62640044 | Benign: not provided | 126,503,221(+) |
C/T NM_033446.3(MVB12B):c.918C>T (p.Leu306=) |
SYNONYMOUS |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv4139n106 | CNV | deletion | 24896259 |
| esv1001649 | CNV | deletion | 20482838 |
| esv1602146 | CNV | deletion | 17803354 |
| esv24101 | CNV | gain+loss | 19812545 |
| esv2628133 | CNV | deletion | 19546169 |
| esv2677987 | CNV | deletion | 23128226 |
| esv26981 | CNV | loss | 19812545 |
| esv27320 | CNV | loss | 19812545 |
| esv3621766 | CNV | gain | 21293372 |
| esv3621767 | CNV | loss | 21293372 |
| nsv1049646 | CNV | gain | 25217958 |
| nsv1076205 | CNV | deletion | 25765185 |
| nsv466563 | CNV | loss | 19166990 |
| nsv509322 | CNV | insertion | 20534489 |
| nsv516074 | CNV | loss | 19592680 |
| nsv521117 | CNV | loss | 19592680 |
| nsv528672 | CNV | gain | 19592680 |
| nsv615311 | CNV | loss | 21841781 |
| nsv951763 | CNV | deletion | 24416366 |
Residual Variation Intolerance Score:
19.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.32;
7.03% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for MVB12B Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MVB12B Gene
Disorders for MVB12B Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| glaucoma, primary open angle |
|
|
Search MVB12B in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for MVB12B
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for MVB12B Gene
Publications for MVB12B Gene
- Identification of human MVB12 proteins as ESCRT-I subunits that function in HIV budding. (PMID: 18005716) Morita E … Sundquist WI (Cell host & microbe 2007) 2 3 4
- Structural basis for membrane targeting by the MVB12-associated β-prism domain of the human ESCRT-I MVB12 subunit. (PMID: 22232651) Boura E … Hurley JH (Proceedings of the National Academy of Sciences of the United States of America 2012) 2 3
- Distinct functions of human MVB12A and MVB12B in the ESCRT-I dependent on their posttranslational modifications. (PMID: 20654576) Tsunematsu T … Konishi H (Biochemical and biophysical research communications 2010) 2 3
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
ExternalLinks
Products for MVB12B Gene
- Custom Antibody ServicesOriGene Antibodies for MVB12B
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for MVB12B
- Origene Custom Protein Services for MVB12B
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MVB12B
- Browse OriGene Inhibitory RNA Products For MVB12B
- OriGene qPCR primer pairs for MVB12B
- OriGene qPCR primer pairs and template standards for MVB12B
- OriGene CRISPR knockouts for MVB12B
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For MVB12B
- Sino Biological Human cDNA Clone for MVB12B
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for MVB12B
- Novus Biologicals proteins and lysates for MVB12B
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for MVB12B (AFLGC-MVB12B)
- VectorBuilder Custom and pre-made DNA vectors for MVB12B (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for MVB12B (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for MVB12B (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for MVB12B CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for MVB12B
- antibodies-online: Show 5 available MVB12B Antibodies ranked by validation data
- Compare Top MVB12B Antibodies
- Quality Products:
- antibodies-online: Search results for available MVB12B related products ranked by validation data
- antibodies-online: Show 4 available MVB12B Proteins ranked by validation data
- Compare Top MVB12B Proteins
- Quality Products:
- Horizon Cell Lines for MVB12B
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MVB12B
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MVB12B
- Search GeneCopoeia for miRNA 3'UTR Target clone products for MVB12B
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MVB12B
Sources for MVB12B Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB