Aliases for MTFP1 Gene
External Ids for MTFP1 Gene
Previous GeneCards Identifiers for MTFP1 Gene
MTP18 is a mitochondrial protein and downstream target of the phosphatidylinositol 3-kinase (see PIK3CA, MIM 171834) signaling pathway that plays a role in cell viability and mitochondrial dynamics (Tondera et al., 2004 [PubMed 15155745]).[supplied by OMIM, Mar 2008]
GeneCards Summary for MTFP1 Gene
MTFP1 (Mitochondrial Fission Process 1) is a Protein Coding gene. Diseases associated with MTFP1 include Corneal Dystrophy And Perceptive Deafness and Optic Atrophy With Or Without Deafness, Ophthalmoplegia, Myopathy, Ataxia, And Neuropathy.
UniProtKB/Swiss-Prot Summary for MTFP1 Gene
Involved in the mitochondrial division probably by regulating membrane fission. Loss-of-function induces the release of cytochrome c, which activates the caspase cascade and leads to apoptosis.