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The protein encoded by this gene is an enzyme found in the outer mitochondrial membrane that reduces N-hydroxylated substrates. The encoded protein uses molybdenum as a cofactor and cytochrome b5 type B and NADH cytochrome b5 reductase as accessory proteins. One type of substrate used is N-hydroxylated nucleotide base analogues, which can be toxic to a cell. Other substrates in... See more...
Aliases for MTARC2 Gene
Aliases for MTARC2 Gene
External Ids for MTARC2 Gene
- HGNC: 26064
- Entrez Gene: 54996
- Ensembl: ENSG00000117791
- OMIM: 614127
- UniProtKB: Q969Z3
Previous HGNC Symbols for MTARC2 Gene
- MOSC2
- MARC2
Summaries for MTARC2 Gene
-
The protein encoded by this gene is an enzyme found in the outer mitochondrial membrane that reduces N-hydroxylated substrates. The encoded protein uses molybdenum as a cofactor and cytochrome b5 type B and NADH cytochrome b5 reductase as accessory proteins. One type of substrate used is N-hydroxylated nucleotide base analogues, which can be toxic to a cell. Other substrates include N(omega)-hydroxy-L-arginine (NOHA) and amidoxime prodrugs, which are activated by the encoded enzyme. Multiple transcript variants encoding the different isoforms have been found for this gene. [provided by RefSeq, Sep 2016]
GeneCards Summary for MTARC2 Gene
MTARC2 (Mitochondrial Amidoxime Reducing Component 2) is a Protein Coding gene. Diseases associated with MTARC2 include Epilepsy, Familial Adult Myoclonic, 3 and Epilepsy, Familial Adult Myoclonic, 2. Among its related pathways are Cytochrome P450 - arranged by substrate type and Metabolism. An important paralog of this gene is MTARC1.
UniProtKB/Swiss-Prot Summary for MTARC2 Gene
-
Catalyzes the reduction of N-oxygenated molecules, acting as a counterpart of cytochrome P450 and flavin-containing monooxygenases in metabolic cycles (PubMed:21029045, PubMed:24423752). As a component of prodrug-converting system, reduces a multitude of N-hydroxylated prodrugs particularly amidoximes, leading to increased drug bioavailability (PubMed:21029045, PubMed:24423752). May be involved in mitochondrial N(omega)-hydroxy-L-arginine (NOHA) reduction, regulating endogenous nitric oxide levels and biosynthesis (PubMed:21029045). Postulated to cleave the N-OH bond of N-hydroxylated substrates in concert with electron transfer from NADH to cytochrome b5 reductase then to cytochrome b5, the ultimate electron donor that primes the active site for substrate reduction (PubMed:21029045).
Additional gene information for MTARC2 Gene
- HGNC(26064)
- Entrez Gene(54996)
- Ensembl(ENSG00000117791)
- OMIM(614127)
- UniProtKB(Q969Z3)
- Open Targets Platform(ENSG00000117791)
- Monarch Initiative
- Search for MTARC2 at DataMed
- Search for MTARC2 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MTARC2 Gene
Genomics for MTARC2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for MTARC2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around MTARC2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for MTARC2
Genomic Locations for MTARC2 Gene
Genomic Locations for MTARC2 Gene
- chr1:220,747,417-220,784,815
- (GRCh38/hg38)
- Size:
- 37,399 bases
- Orientation:
- Plus strand
- chr1:220,921,567-220,958,150
- (GRCh37/hg19)
- Size:
- 36,584 bases
- Orientation:
- Plus strand
Genomic View for MTARC2 Gene
Genes around MTARC2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1q41 by HGNC
- 1q41 by Entrez Gene
- 1q41 by Ensembl
MTARC2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MTARC2 Gene
Proteins for MTARC2 Gene
-
Protein details for MTARC2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q969Z3-MARC2_HUMAN
- Recommended name:
- Mitochondrial amidoxime reducing component 2
- Protein Accession:
- Q969Z3
- B2D0R5
- D3DTB3
- Q0JSK7
- Q5VT67
- Q5VXC7
- Q7L317
- Q9H066
- Q9NWU0
Protein attributes for MTARC2 Gene
- Size:
- 335 amino acids
- Molecular mass:
- 38023 Da
- Cofactor:
- Name=Mo-molybdopterin; Xref=ChEBI:CHEBI:71302;
- Quaternary structure:
-
- Component of a complex composed of cytochrome b5, NADH-cytochrome b5 reductase (CYB5R3) and MTARC2.
- SequenceCaution:
-
- Sequence=BAA91287.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
Post-translational modifications for MTARC2 Gene
- Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30.
-
Ubiquitination at Lys59, Lys138, Lys144, Lys166, Lys173, Lys187, Lys287, and Lys294
- NX_Q969Z3 (NX_Q969Z3-1)
- Modification sites at PhosphoSitePlus
Other Protein References for MTARC2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Creative Diagnostics Anti-MARC2 (C-terminal) polyclonal antibody
-
Custom Antibody ServicesOriGene Antibodies for MTARC2
- Novus Biologicals Antibodies for MTARC2
-
Abcam antibodies for MTARC2
- Invitrogen Antibodies for MTARC2 (AFLGC-MARC2)
-
Biorbyt antibodies for MTARC2
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for MTARC2
- Origene Custom Protein Services for MTARC2
- antibodies-online: Show 4 available MARC2 Proteins ranked by validation data
- Compare Top MARC2 Proteins
-
Quality Products:
No data available for DME Specific Peptides for MTARC2 Gene
Domains & Families for MTARC2 Gene
Gene Families for MTARC2 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Predicted membrane proteins
Protein Domains for MTARC2 Gene
- InterPro:
- Blocks:
-
- MOSC domain
- ProtoNet:
Suggested Antigen Peptide Sequences for MTARC2 Gene
- GenScript: Design optimal peptide antigens:
-
- MOSC domain-containing protein 2, mitochondrial (MOSC2_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MTARC2 Gene
Function for MTARC2 Gene
Molecular function for MTARC2 Gene
- UniProtKB/Swiss-Prot Function:
- Catalyzes the reduction of N-oxygenated molecules, acting as a counterpart of cytochrome P450 and flavin-containing monooxygenases in metabolic cycles (PubMed:21029045, PubMed:24423752). As a component of prodrug-converting system, reduces a multitude of N-hydroxylated prodrugs particularly amidoximes, leading to increased drug bioavailability (PubMed:21029045, PubMed:24423752). May be involved in mitochondrial N(omega)-hydroxy-L-arginine (NOHA) reduction, regulating endogenous nitric oxide levels and biosynthesis (PubMed:21029045). Postulated to cleave the N-OH bond of N-hydroxylated substrates in concert with electron transfer from NADH to cytochrome b5 reductase then to cytochrome b5, the ultimate electron donor that primes the active site for substrate reduction (PubMed:21029045).
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=2 [Fe(II)-cytochrome b5] + 2 H(+) + N(omega)-hydroxy-L-arginine = 2 [Fe(III)-cytochrome b5] + H2O + L-arginine; Xref=Rhea:RHEA:61644, Rhea:RHEA-COMP:10438, Rhea:RHEA-COMP:10439, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:29033, ChEBI:CHEBI:29034, ChEBI:CHEBI:32682, ChEBI:CHEBI:60107; Evidence={ECO:0000269|PubMed:21029045};.
- UniProtKB/Swiss-Prot BiophysicochemicalProperties:
- Kinetic parameters: KM=830 uM for benzamidoxime {ECO:0000269|PubMed:21029045, ECO:0000269|PubMed:24423752}; KM=400 uM for benzamidoxime (at pH 6.0 and 37 degrees Celsius) {ECO:0000269|PubMed:24423752}; KM=3 mM for NOHA {ECO:0000269|PubMed:21029045, ECO:0000269|PubMed:24423752}; KM=3.7 mM for NHAM {ECO:0000269|PubMed:21029045, ECO:0000269|PubMed:24423752}; Vmax=307 nmol/min/mg enzyme toward benzamidoxime {ECO:0000269|PubMed:21029045, ECO:0000269|PubMed:24423752}; Vmax=119 nmol/min/mg enzyme toward benzamidoxime (at pH 6.0 and 37 degrees Celsius) {ECO:0000269|PubMed:24423752}; Vmax=373 nmol/min/mg enzyme toward NOHA {ECO:0000269|PubMed:21029045, ECO:0000269|PubMed:24423752}; Vmax=36.5 nmol/min/mg enzyme toward NHAM {ECO:0000269|PubMed:21029045, ECO:0000269|PubMed:24423752};
Enzyme Numbers (IUBMB) for MTARC2 Gene
Phenotypes From GWAS Catalog for MTARC2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003824 | catalytic activity | IEA | -- |
| GO:0008940 | nitrate reductase activity | IDA | 20861021 |
| GO:0016491 | oxidoreductase activity | IEA | -- |
| GO:0030151 | molybdenum ion binding | IEA,IDA | 20861021 |
| GO:0030170 | pyridoxal phosphate binding | IEA | -- |
Phenotypes for MTARC2 Gene
- MGI mutant phenotypes for MTARC2:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for MTARC2:
-
- Increased vaccinia virus (VACV) infection
- no effect
- Decreased viability
- Decreased viability ratio
- Strongly decreased CFP-tsO45G cell surface transport
- Synthetic lethal with MLN4924 (a NAE inhibitor)
- Decreased shRNA abundance
- Decreased human papilloma virus 16 (HPV16) pseudovirus infection
- Decreased Salmonella proliferation
- Increased viability with MLN4924 (a NAE inhibitor)
- Decreased ionizing radiation sensitivity
- Decreased circadian period length
Animal Models for MTARC2 Gene
- MGI Knock Outs for MTARC2:
-
- Mtarc2 Mtarc2<tm2a(EUCOMM)Hmgu>
Animal Model Products
-
Taconic Biosciences Mouse Models for MTARC2
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for MTARC2 - Select products 50% OFF >
- * MTARC2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for MTARC2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MTARC2
miRNA for MTARC2 Gene
- miRTarBase miRNAs that target MTARC2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MTARC2
- Browse OriGene Inhibitory RNA Products For MTARC2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MTARC2
Clone Products
- Applied Biological Materials (abm): Clones for MTARC2 - Select products 50% OFF >
- * MTARC2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for MTARC2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MTARC2
Cell Line Products
-
Horizon Cell Lines for MTARC2
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for MTARC2 Gene
Localization for MTARC2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for MTARC2 Gene
- Mitochondrion outer membrane. Peripheral membrane protein. Peroxisome.
| Compartment | Confidence |
|---|---|
| mitochondrion | 5 |
| peroxisome | 3 |
| cytosol | 3 |
| nucleus | 2 |
| cytoskeleton | 1 |
| endoplasmic reticulum | 1 |
| golgi apparatus | 1 |
| plasma membrane | 0 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005739 | mitochondrion | IDA,ISS | -- |
| GO:0005741 | mitochondrial outer membrane | TAS | -- |
| GO:0005777 | peroxisome | IEA | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for MTARC2 Gene
Pathways & Interactions for MTARC2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Cytochrome P450 - arranged by substrate type | ||
| 2 | Metabolism |
.40
|
|
Pathways by source for MTARC2 Gene
3 Reactome pathways for MTARC2 Gene
Interacting Proteins for MTARC2 Gene
GPS-Prot Interaction Network for MTARC2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006805 | xenobiotic metabolic process | TAS | -- |
| GO:0042126 | nitrate metabolic process | IDA | 20861021 |
| GO:0051410 | detoxification of nitrogen compound | NAS | 20861021 |
| GO:0055114 | oxidation-reduction process | IEA,IDA | 20861021 |
No data available for SIGNOR curated interactions for MTARC2 Gene
Transcripts for MTARC2 Gene
mRNA/cDNA for MTARC2 Gene
- 3 REFSEQ mRNAs :
- 9 NCBI additional mRNA sequence :
- 6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000359316 1335 nts (view in UCSC)
- ENST00000366913 2146 nts (view in UCSC)
- ENST00000425560 585 nts (view in UCSC)
- ENST00000469583 758 nts (view in UCSC)
- ENST00000472447 699 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for MTARC2 - Select products 50% OFF >
- * MTARC2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for MTARC2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MTARC2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MTARC2
- Browse OriGene Inhibitory RNA Products For MTARC2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MTARC2
Clone Products
- Applied Biological Materials (abm): Clones for MTARC2 - Select products 50% OFF >
- * MTARC2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for MTARC2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MTARC2
Relevant External Links for MTARC2 Gene
- GeneLoc Exon Structure for
- MTARC2
Expression for MTARC2 Gene
SOURCE GeneReport for Unigene cluster for MTARC2 Gene:
Hs.369042Evidence on tissue expression from TISSUES for MTARC2 Gene
- Liver(4.5)
- Lung(4.3)
- Intestine(4.2)
- Kidney(2.6)
No Expression Related Data Available
Primer Products
-
OriGene qPCR primer pairs for MTARC2
-
OriGene qPCR primer pairs and template standards for MTARC2
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for MTARC2 Gene
Orthologs for MTARC2 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | MOSC2 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | MOSC2 30 |
|
||
| MARC2 31 |
|
OneToOne | |||
| Dog (Canis familiaris) |
Mammalia | MARC2 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Marc2 30 31 |
|
OneToOne | |
| Mtarc2 17 |
|
||||
| Rat (Rattus norvegicus) |
Mammalia | LOC100910481 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | MARC2 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | MARC2 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | -- 31 |
|
OneToMany | |
| Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
ManyToMany | |
| -- 31 |
|
ManyToMany | |||
| -- 31 |
|
ManyToMany | |||
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | marc1 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | MARC2 31 |
|
OneToMany | |
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG1665 31 |
|
OneToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | F56A11.5 31 |
|
ManyToMany | |
| F22B8.7 31 |
|
ManyToMany | |||
| F53E10.1 31 |
|
ManyToMany | |||
| Thale Cress (Arabidopsis thaliana) |
eudicotyledons | AT5G44720 30 |
|
||
| Rice (Oryza sativa) |
Liliopsida | Os09g0560800 30 |
|
||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
- Species where no ortholog for MTARC2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for MTARC2 Gene
- ENSEMBL:
- Gene Tree for MTARC2 (if available)
- TreeFam:
- Gene Tree for MTARC2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for MTARC2: view image
Paralogs for MTARC2 Gene
Pseudogenes.org Pseudogenes for MTARC2 Gene
Variants for MTARC2 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MTARC2 Gene
| SNP ID | Clinical significance and condition | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs3795535 | - | p.Gly244Ser | |||
| rs72472370 | - | p.Ala3Ser | |||
| rs76664695 | - | p.Cys245Trp |
Residual Variation Intolerance Score:
71.8% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for MTARC2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MTARC2
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MTARC2 Gene
Disorders for MTARC2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| epilepsy, familial adult myoclonic, 3 |
|
|
| epilepsy, familial adult myoclonic, 2 |
|
|
| ivic syndrome |
|
|
| familial adult myoclonic epilepsy |
|
|
Search MTARC2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for MTARC2
No data available for UniProtKB/Swiss-Prot and Genatlas for MTARC2 Gene
Publications for MTARC2 Gene
- Functional characterization of protein variants encoded by nonsynonymous single nucleotide polymorphisms in MARC1 and MARC2 in healthy Caucasians. (PMID: 24423752) Ott G … Havemeyer A (Drug metabolism and disposition: the biological fate of chemicals 2014) 3 4
- Reduction of N(ω)-hydroxy-L-arginine by the mitochondrial amidoxime reducing component (mARC). (PMID: 21029045) Kotthaus J … Clement B (The Biochemical journal 2011) 3 4
- The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 3 4
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
ExternalLinks
Products for MTARC2 Gene
- Custom Antibody ServicesOriGene Antibodies for MTARC2
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for MTARC2
- Origene Custom Protein Services for MTARC2
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- Browse OriGene Inhibitory RNA Products For MTARC2
- OriGene qPCR primer pairs for MTARC2
- OriGene qPCR primer pairs and template standards for MTARC2
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- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- Sino Biological Human cDNA Clone for MTARC2
- Browse Sino Biological Recombinant Proteins
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- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for MTARC2
- Novus Biologicals proteins and lysates for MTARC2
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for MTARC2
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Taconic Biosciences Mouse Models for MTARC2
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for MTARC2 (AFLGC-MARC2)
- VectorBuilder Custom and pre-made DNA vectors for MTARC2 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for MTARC2 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for MTARC2 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for MTARC2 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for MTARC2
- antibodies-online: Show 18 available MARC2 Antibodies ranked by validation data
- Compare Top MARC2 Antibodies
- antibodies-online: Search results for available MARC2 related products ranked by validation data
- antibodies-online: Show 4 available MARC2 Proteins ranked by validation data
- Compare Top MARC2 Proteins
- Quality Products:
- Horizon Cell Lines for MTARC2
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MTARC2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MTARC2
- Search GeneCopoeia for miRNA 3'UTR Target clone products for MTARC2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MTARC2
- Biorbyt antibodies for MTARC2
Sources for MTARC2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
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