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MTARC1 (Mitochondrial Amidoxime Reducing Component 1) is a Protein Coding gene. Diseases associated with MTARC1 include Good Syndrome. Among its related pathways are Cytochrome P450 - arranged by substrate type and Metabolism. An important paralog of this gene is ENSG00000286231.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003824 | catalytic activity | IEA | -- |
GO:0008940 | nitrate reductase activity | IDA | 20861021 |
GO:0016491 | oxidoreductase activity | IEA | -- |
GO:0030151 | molybdenum ion binding | IEA,IDA | 20861021 |
GO:0030170 | pyridoxal phosphate binding | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005739 | mitochondrion | IDA,ISS | 20861021 |
GO:0005741 | mitochondrial outer membrane | TAS | -- |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Cytochrome P450 - arranged by substrate type | ||
2 | Metabolism |
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GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006805 | xenobiotic metabolic process | TAS | -- |
GO:0042126 | nitrate metabolic process | IDA | 20861021 |
GO:0051410 | detoxification of nitrogen compound | NAS | 20861021 |
GO:0055114 | oxidation-reduction process | IEA,IDA | 20861021 |
Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
---|---|---|---|---|---|---|
Molybdenum | Approved | Pharma | 23 |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | MOSC1 30 |
|
||
MARC1 31 |
|
OneToOne | |||
Dog (Canis familiaris) |
Mammalia | MARC1 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | MARC1 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Marc1 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Marc1 30 31 |
|
OneToOne | |
Mtarc1 17 |
|
||||
Platypus (Ornithorhynchus anatinus) |
Mammalia | MARC1 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | MARC2 30 |
|
||
-- 31 |
|
OneToMany | |||
Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
ManyToMany | |
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
-- 31 |
|
ManyToMany | |||
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | LOC100487963 30 |
|
||
African clawed frog (Xenopus laevis) |
Amphibia | Xl.25253 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | zgc:110783 30 |
|
||
MARC2 31 |
|
OneToMany | |||
Fruit Fly (Drosophila melanogaster) |
Insecta | CG1665 31 |
|
OneToMany | |
Worm (Caenorhabditis elegans) |
Secernentea | F56A11.5 30 31 |
|
ManyToMany | |
F53E10.1 31 |
|
ManyToMany | |||
F22B8.7 31 |
|
ManyToMany | |||
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
SNP ID | Clinical significance and condition | Chr 01 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
708513 | Benign: not provided | 220,796,753(+) | T/A | MISSENSE_VARIANT | |
773642 | Benign: not provided | 220,791,501(+) | G/C | MISSENSE_VARIANT | |
773643 | Benign: not provided | 220,797,921(+) | G/A | SYNONYMOUS_VARIANT | |
779860 | Benign: not provided | 220,791,572(+) | C/T | SYNONYMOUS_VARIANT | |
787652 | Benign: not provided | 220,813,282(+) | C/T | INTRON_VARIANT |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv1008867 | CNV | deletion | 20482838 |
Disorder | Aliases | PubMed IDs |
---|---|---|
good syndrome |
|
|