Aliases for MTA2 Gene
Aliases for MTA2 Gene
External Ids for MTA2 Gene
- HGNC: 7411
- Entrez Gene: 9219
- Ensembl: ENSG00000149480
- OMIM: 603947
- UniProtKB: O94776
Previous HGNC Symbols for MTA2 Gene
- MTA1L1
Previous GeneCards Identifiers for MTA2 Gene
- GC11M062136
- GC11M062119
- GC11M062360
- GC11M058689
Summaries for MTA2 Gene
-
This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacetylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis. [provided by RefSeq, May 2011]
GeneCards Summary for MTA2 Gene
MTA2 (Metastasis Associated 1 Family Member 2) is a Protein Coding gene. Among its related pathways are Gene Expression and Regulation of TP53 Activity. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and chromatin binding. An important paralog of this gene is MTA1.
UniProtKB/Swiss-Prot for MTA2 Gene
-
May be involved in the regulation of gene expression as repressor and activator. The repression might be related to covalent modification of histone proteins.
Additional gene information for MTA2 Gene
- Monarch Initiative
- Search for MTA2 at DataMed
- Search for MTA2 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MTA2 Gene
Genomics for MTA2 Gene
GeneHancer (GH) Regulatory Elements for MTA2 Gene
Promoters and enhancers for MTA2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around MTA2 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for MTA2 Gene
Genomic Locations for MTA2 Gene
- chr11:62,593,203-62,601,840
- (GRCh38/hg38)
- Size:
- 8,638 bases
- Orientation:
- Minus strand
- chr11:62,360,675-62,369,312
- (GRCh37/hg19)
Genomic View for MTA2 Gene
Genes around MTA2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 11q12.3 by Ensembl
- 11q12.3 by Entrez Gene
- 11q12.3 by HGNC
MTA2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MTA2 Gene
Proteins for MTA2 Gene
-
Protein details for MTA2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O94776-MTA2_HUMAN
- Recommended name:
- Metastasis-associated protein MTA2
- Protein Accession:
- O94776
- Q68DB1
- Q9UQB5
Protein attributes for MTA2 Gene
- Size:
- 668 amino acids
- Molecular mass:
- 75023 Da
- Quaternary structure:
-
- Component of the nucleosome-remodeling and histone-deacetylase multiprotein complex (NuRD). Interacts with HDAC7, p53/TP53, MINT and MBD3 (By similarity). Interacts with PIMREG. Interacts with NACC2.
- SequenceCaution:
-
- Sequence=AAH23656.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305};
Protein Expression for MTA2 Gene
Post-translational modifications for MTA2 Gene
Other Protein References for MTA2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for MTA2
- Novus Biologicals Antibodies for MTA2
-
Abcam antibodies for MTA2
-
Cloud-Clone Corp. Antibodies for MTA2
- Invitrogen Antibodies for MTA2
- GeneTex MTA2 antibody for MTA2
-
Custom Antibody ServicesProSci Antibodies for MTA2
-
Santa Cruz Biotechnology (SCBT) Antibodies for MTA2
Protein Products
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- Novus Biologicals proteins for MTA2
-
Cloud-Clone Corp. Proteins for MTA2
- Search GeneTex for Proteins for MTA2
-
Abcam proteins for MTA2
Assay Products
-
Cloud-Clone Corp. Assay Kits for MTA2
No data available for DME Specific Peptides for MTA2 Gene
Domains & Families for MTA2 Gene
Gene Families for MTA2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
- Transcription factors
Protein Domains for MTA2 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for MTA2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for MTA2 Gene
Function for MTA2 Gene
Molecular function for MTA2 Gene
- UniProtKB/Swiss-Prot Function:
- May be involved in the regulation of gene expression as repressor and activator. The repression might be related to covalent modification of histone proteins.
Phenotypes From GWAS Catalog for MTA2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000976 | contributes_to transcription regulatory region sequence-specific DNA binding | IDA | 16217013 |
| GO:0000989 | transcription factor activity, transcription factor binding | IEA | -- |
| GO:0001085 | RNA polymerase II transcription factor binding | IPI | 15920471 |
| GO:0001103 | RNA polymerase II repressing transcription factor binding | IPI | 22926524 |
| GO:0003677 | DNA binding | IEA | -- |
Phenotypes for MTA2 Gene
- MGI mutant phenotypes for MTA2:
-
inferred from 2 alleles
- homeostasis/metabolism phenotype
- mortality/aging
- immune system phenotype
- cellular phenotype
- growth/size/body region phenotype
- reproductive system phenotype
- integument phenotype
- hematopoietic system phenotype
- skeleton phenotype
- renal/urinary system phenotype
- liver/biliary system phenotype
- craniofacial phenotype
- GenomeRNAi human phenotypes for MTA2:
-
- Increased viability
- Increased vaccinia virus (VACV) infection
- shRNA abundance <= 50%
- Synthetic lethal with Ras
- Dynamic nuclei (hole, folded or small irregular)
- Decreased NF-kappaB reporter expression
- Decreased Salmonella enterica Typhimurium invasion
- Decreased cell migration
- Increased cell migration
Animal Models for MTA2 Gene
- MGI Knock Outs for MTA2:
-
- Mta2 tm1.1Yzha
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MTA2
-
-
ViGene Biosciences lentiviral particle packaged cDNA for MTA2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for MTA2 gene
- Search ViGene Biosciences for MTA2
CRISPR Products
-
OriGene CRISPR knockouts for MTA2
- genomics-online: gRNA clones - Search results for 85 available MTA2 gene related products
- Overview of 85 available MTA2 gene related products
- Applied Biological Materials CRISPR for MTA2
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for MTA2
- GenScript: Design CRISPR guide RNA sequences for MTA2
miRNA for MTA2 Gene
- miRTarBase miRNAs that target MTA2
-
- hsa-mir-559 (MIRT004116)
- hsa-mir-661 (MIRT004117)
- hsa-mir-146a-5p (MIRT004731)
- hsa-mir-335-5p (MIRT017668)
- hsa-mir-34a-5p (MIRT025233)
- hsa-mir-125b-2-3p (MIRT038634)
- hsa-mir-615-3p (MIRT040292)
- hsa-mir-548a-3p (MIRT040512)
- hsa-mir-505-3p (MIRT041029)
- hsa-mir-423-3p (MIRT042480)
- hsa-mir-365a-3p (MIRT044044)
- hsa-mir-186-5p (MIRT044965)
- hsa-mir-222-3p (MIRT046730)
miRNA Products
- Search ViGene Biosciences for MTA2
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for MTA2
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- genomics-online: shRNA clones - Search results for 85 available MTA2 gene related products
- Overview of 85 available MTA2 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for MTA2 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for MTA2
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MTA2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for MTA2
-
ViGene Biosciences adenoviral particle packaged cDNA for MTA2 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for MTA2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for MTA2 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for MTA2 Gene
Localization for MTA2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for MTA2 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 2 |
- Nucleoplasm (4)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000118 | histone deacetylase complex | TAS | 10444591 |
| GO:0000790 | nuclear chromatin | IDA,HDA | 16217013 |
| GO:0005634 | nucleus | IEA | -- |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005667 | transcription factor complex | IDA | 15920471 |
Pathways & Interactions for MTA2 Gene
Pathways by source for MTA2 Gene
1 BioSystems pathway for MTA2 Gene
2 GeneGo (Thomson Reuters) pathways for MTA2 Gene
Interacting Proteins for MTA2 Gene
Selected Interacting proteins:
O94776-MTA2_HUMAN
ENSP00000278823
for MTA2 Gene via
IID
STRING
UniProtKB
MINT
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000122 | negative regulation of transcription by RNA polymerase II | IEA | -- |
| GO:0006306 | DNA methylation | IEA | -- |
| GO:0006333 | chromatin assembly or disassembly | TAS | 10444591 |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0010762 | regulation of fibroblast migration | IEA | -- |
No data available for SIGNOR curated interactions for MTA2 Gene
Transcripts for MTA2 Gene
mRNA/cDNA for MTA2 Gene
- (3) REFSEQ mRNAs :
- (6) Additional mRNA sequences :
- (3) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for MTA2 Gene
CRISPR Products
-
OriGene CRISPR knockouts for MTA2
- genomics-online: gRNA clones - Search results for 85 available MTA2 gene related products
- Overview of 85 available MTA2 gene related products
- Applied Biological Materials CRISPR for MTA2
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for MTA2
- GenScript: Design CRISPR guide RNA sequences for MTA2
miRNA Products
- Search ViGene Biosciences for MTA2
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for MTA2
- Browse OriGene Inhibitory RNA Products For MTA2
- genomics-online: shRNA clones - Search results for 85 available MTA2 gene related products
- Overview of 85 available MTA2 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for MTA2 gene
Clone Products
- VectorBuilder custom plasmid, inducible vectors for MTA2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MTA2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MTA2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8a | · | 8b | · | 8c | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18a | · | 18b | ^ | 19 | ^ |
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| SP9: |
| ExUns: | 20a | · | 20b | ^ | 21 |
|---|---|---|---|---|---|
| SP1: | |||||
| SP2: | |||||
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| SP9: |
Expression for MTA2 Gene
This gene is overexpressed in Peripheral blood mononuclear cells (18.1), Breast (8.6), and Lymph node (8.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for MTA2 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of MTA2 Gene:
MTA2SOURCE GeneReport for Unigene cluster for MTA2 Gene:
Hs.173043mRNA Expression by UniProt/SwissProt for MTA2 Gene:
O94776-MTA2_HUMAN
Tissue specificity:
Widely expressed.
Evidence on tissue expression from TISSUES for MTA2 Gene
- Nervous system(4.3)
- Eye(4.2)
- Liver(4.2)
- Lymph node(2.6)
- Intestine(2)
Primer Products
-
OriGene qPCR primer pairs for MTA2
-
OriGene qPCR primer pairs and template standards for MTA2
- genomics-online: primer clones - Search results for 85 available MTA2 gene related products
- Overview of 85 available MTA2 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for MTA2 Gene
Orthologs for MTA2 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | MTA2 34 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | MTA2 34 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | MTA2 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | MTA2 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Mta2 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Mta2 33 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | MTA2 34 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | MTA2 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | mta2 33 |
|
||
| Str.6927 33 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.545 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | mta2 33 34 |
|
||
| wufi29g02 33 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | MTA1-like 34 |
|
OneToOne | |
| worm (Caenorhabditis elegans) |
Secernentea | lin-40 34 |
|
OneToOne | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToOne |
- Species where no ortholog for MTA2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for MTA2 Gene
(4) SIMAP similar genes for MTA2 Gene using alignment to 1 proteins:
Variants for MTA2 Gene
| SNP ID | Clin | Chr 11 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000199823 | -- | 62,594,840(-) | A/C | intron_variant | |
| rs1000446112 | -- | 62,598,835(-) | A/G | intron_variant | |
| rs1000692205 | -- | 62,601,142(-) | C/T | 5_prime_UTR_variant, intron_variant | |
| rs1001183217 | -- | 62,598,187(-) | G/A | intron_variant | |
| rs1001237165 | -- | 62,598,444(-) | C/T | intron_variant |
Residual Variation Intolerance Score:
3.46% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.63;
13.44% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for MTA2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MTA2
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MTA2 Gene
Disorders for MTA2 Gene
Additional Disease Information for MTA2
No disorders were found for MTA2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MTA2 Gene
Publications for MTA2 Gene
- Molecular cloning, mapping, and characterization of a novel human gene, MTA1-L1, showing homology to a metastasis-associated gene, MTA1. (PMID: 9929979) Futamura M … Tokino T (Journal of human genetics 1999) 2 3 4 22 58
- RBB, a novel transcription repressor, represses the transcription of HDM2 oncogene. (PMID: 22926524) Xuan C … Shang Y (Oncogene 2013) 3 4 58
- Overexpression of metastasis-associated protein 2 is associated with hepatocellular carcinoma size and differentiation. (PMID: 19702911) Lee H … Kim KW (Journal of gastroenterology and hepatology 2009) 3 22 58
- Members of the NuRD chromatin remodeling complex interact with AUF1 in developing cortical neurons. (PMID: 18413351) Lee C … Agoston DV (Cerebral cortex (New York, N.Y. : 1991) 2008) 3 22 58
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen JV … Mann M (Cell 2006) 3 4 58
Products for MTA2 Gene
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- Cyagen custom Knockout/knockin (KOKI) mouse models for MTA2
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- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MTA2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 114 available MTA2 Antibodies ranked by validation data
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- GeneTex MTA2 antibody for MTA2
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- genomics-online: cdna clones - Search results for 85 available MTA2 gene related products
- Overview of 85 available MTA2 gene related products
- orf clones - Search results for 85 available MTA2 gene related products
- Overview of 85 available MTA2 gene related products
- genomics-online: gRNA clones - Search results for 85 available MTA2 gene related products
- Overview of 85 available MTA2 gene related products
- genomics-online: primer clones - Search results for 85 available MTA2 gene related products
- Overview of 85 available MTA2 gene related products
- genomics-online: shRNA clones - Search results for 85 available MTA2 gene related products
- Overview of 85 available MTA2 gene related products
Sources for MTA2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151)