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Aliases for MT-TR Gene

Subcategory (RNA class) for MT-TR Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for MT-TR Gene

  • Mitochondrially Encoded TRNA Arginine 2 5
  • TRNA Arginine 2
  • TRNA 3
  • TRNR 3
  • MTTR 3

External Ids for MT-TR Gene

Previous HGNC Symbols for MT-TR Gene

  • MTTR

Previous GeneCards Identifiers for MT-TR Gene

  • GC00U921611

Summaries for MT-TR Gene

GeneCards Summary for MT-TR Gene

MT-TR (Mitochondrially Encoded TRNA Arginine) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with MT-TR include Mitochondrial Disorders and Mitochondrial Encephalomyopathy. Among its related pathways are tRNA Aminoacylation.

Additional gene information for MT-TR Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MT-TR Gene

Genomics for MT-TR Gene

Genomic Locations for MT-TR Gene

Genomic Locations for MT-TR Gene
chrMT:10,405-10,469
(GRCh38/hg38)
Size:
65 bases
Orientation:
Plus strand
chrMT:10,405-10,469
(GRCh37/hg19)

Genomic View for MT-TR Gene

Genes around MT-TR on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for MT-TR Gene

No data available for GeneHancer (GH) Regulatory Elements for MT-TR Gene

Proteins for MT-TR Gene

Post-translational modifications for MT-TR Gene

No Post-translational modifications

No data available for DME Specific Peptides for MT-TR Gene

Domains & Families for MT-TR Gene

Gene Families for MT-TR Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MT-TR: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MT-TR Gene

Function for MT-TR Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MT-TR Gene

Localization for MT-TR Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MT-TR gene
Compartment Confidence
mitochondrion 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MT-TR Gene

Pathways & Interactions for MT-TR Gene

SuperPathways for MT-TR Gene

SuperPathway Contained pathways
1 tRNA Aminoacylation
genes like me logo Genes that share pathways with MT-TR: view

Pathways by source for MT-TR Gene

1 KEGG pathway for MT-TR Gene

Interacting Proteins for MT-TR Gene

Gene Ontology (GO) - Biological Process for MT-TR Gene

None

No data available for SIGNOR curated interactions for MT-TR Gene

Drugs & Compounds for MT-TR Gene

No Compound Related Data Available

Transcripts for MT-TR Gene

mRNA/cDNA for MT-TR Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MT-TR Gene

No ASD Table

Relevant External Links for MT-TR Gene

GeneLoc Exon Structure for
MT-TR
ECgene alternative splicing isoforms for
MT-TR

Expression for MT-TR Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MT-TR Gene

genes like me logo Genes that share expression patterns with MT-TR: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MT-TR Gene

Orthologs for MT-TR Gene

Evolution for MT-TR Gene

ENSEMBL:
Gene Tree for MT-TR (if available)
TreeFam:
Gene Tree for MT-TR (if available)

No data available for Orthologs for MT-TR Gene

Paralogs for MT-TR Gene

No data available for Paralogs for MT-TR Gene

Variants for MT-TR Gene

Additional Variant Information for MT-TR Gene

Human Gene Mutation Database (HGMD)
MT-TR
SNPedia medical, phenotypic, and genealogical associations of SNPs for
MT-TR

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MT-TR Gene

Disorders for MT-TR Gene

MalaCards: The human disease database

(3) MalaCards diseases for MT-TR Gene - From: HGMD, ClinVar, GTR, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
mitochondrial disorders
  • mitochondrial encephalomyopathies
mitochondrial encephalomyopathy
  • mitochondrial encephalomyopathies
amyloidosis, hereditary, transthyretin-related
  • hereditary amyloidosis, transthyretin-related
- elite association - COSMIC cancer census association via MalaCards
Search MT-TR in MalaCards View complete list of genes associated with diseases

Additional Disease Information for MT-TR

Genetic Association Database
(GAD)
genes like me logo Genes that share disorders with MT-TR: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MT-TR Gene

Publications for MT-TR Gene

  1. Molecular epidemiology of childhood mitochondrial encephalomyopathies in a Finnish population: sequence analysis of entire mtDNA of 17 children reveals heteroplasmic mutations in tRNAArg, tRNAGlu, and tRNALeu(UUR) genes. (PMID: 15286228) Uusimaa J … Majamaa K (Pediatrics 2004) 3 44 58
  2. Genetic polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) in ethnic populations in Texas; a report of a novel MTHFR polymorphic site, G1793A. (PMID: 11807892) Rady PL … Matalon RK (American journal of medical genetics 2002) 3 44 58
  3. A novel mitochondrial tRNA Arg mutation resulting in an anticodon swap in a patient with mitochondrial encephalomyopathy. (PMID: 22781096) Roos S … Oldfors A (European journal of human genetics : EJHG 2013) 3 58
  4. MtSNPscore: a combined evidence approach for assessing cumulative impact of mitochondrial variations in disease. (PMID: 19758471) Bhardwaj A … Tiwari S (BMC bioinformatics 2009) 3 58
  5. Comprehensive analysis of common mitochondrial DNA variants and colorectal cancer risk. (PMID: 19050702) Webb E … Houlston RS (British journal of cancer 2008) 3 58

Products for MT-TR Gene

Sources for MT-TR Gene

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