Aliases for MT-TQ Gene

Data sources for MT-TQ Gene:

RNA type for MT-TQ Gene

tRNA

Aliases for MT-TQ Gene

External Ids for MT-TQ Gene

Previous HGNC Symbols for MT-TQ Gene

  • MTTQ

Previous GeneCards Identifiers for MT-TQ Gene

  • GC00U921610

Summaries for MT-TQ Gene

GeneCards Summary for MT-TQ Gene

MT-TQ (Mitochondrially Encoded TRNA-Gln (CAA/G)) is an RNA Gene, and is affiliated with the tRNA class. Diseases associated with MT-TQ include Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, And Stroke-Like Episodes and Mitochondrial Encephalomyopathy Lactic Acidosis And Stroke-Like Episodes. Among its related pathways are tRNA Aminoacylation.

Rfam classification for MT-TQ Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MT-TQ Gene

Genomics for MT-TQ Gene

Genomic Locations for MT-TQ Gene

Latest Assembly
chrMT:4,320-4,401
(GRCh38/hg38)
Size:
82 bases
Orientation:
Minus strand

Previous Assembly
chrMT:4,329-4,400
(GRCh37/hg19 by Ensembl)
Size:
72 bases
Orientation:
Minus strand

Genomic View for MT-TQ Gene

Genes around MT-TQ on UCSC Golden Path with GeneCards custom track
MT-TQ in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for MT-TQ Gene

No data available for GeneHancer (GH) Regulatory Elements for MT-TQ Gene

Proteins for MT-TQ Gene

Post-translational modifications for MT-TQ Gene

No Post-translational modifications

No data available for DME Specific Peptides for MT-TQ Gene

Domains & Families for MT-TQ Gene

Gene Families for MT-TQ Gene

genes like me logo Genes that share domains with MT-TQ: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MT-TQ Gene

Function for MT-TQ Gene

Human Phenotype Ontology for MT-TQ Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MT-TQ Gene

Localization for MT-TQ Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MT-TQ gene
Compartment Confidence
mitochondrion 3
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MT-TQ Gene

Pathways & Interactions for MT-TQ Gene

PathCards logo

SuperPathways for MT-TQ Gene

SuperPathway Contained pathways
1 tRNA Aminoacylation
genes like me logo Genes that share pathways with MT-TQ: view

Pathways by source for MT-TQ Gene

1 KEGG pathway for MT-TQ Gene

Gene Ontology (GO) - Biological Process for MT-TQ Gene

None

No data available for Interacting Proteins and SIGNOR curated interactions for MT-TQ Gene

Drugs & Compounds for MT-TQ Gene

No Compound Related Data Available

Transcripts for MT-TQ Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MT-TQ Gene

RNAcentral Transcript ID RNA Type Length (nts) # of Sources Source Identifiers and Annotations
URS000019B78E_9606 tRNA 72 3

Ensembl: ENST00000387372 (view in UCSC) ,

Rfam: RF00005,

ENA: View 50511 records in RNAcentral

URS00002337B8_9606 tRNA 81 1

ENA: AY245555.1:4328..4408:tRNA, V00662.1:4320..4400:tRNA,

URS00000433C6_9606 tRNA 72 1

ENA: View 12 records in RNAcentral

URS00000A0499_9606 tRNA 72 1

ENA: HQ012201.1:4326..4397:tRNA, HQ012202.1:4326..4397:tRNA, HQ012210.1:4325..4396:tRNA, KF162714.1:4329..4400:tRNA,

URS00000AA031_9606 tRNA 72 1

ENA: View 59 records in RNAcentral

MT-TQ in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Alternative Splicing Database (ASD) splice patterns (SP) for MT-TQ Gene

No ASD Table

Relevant External Links for MT-TQ Gene

GeneLoc Exon Structure for
MT-TQ

No data available for mRNA/cDNA for MT-TQ Gene

Expression for MT-TQ Gene

Phenotype-based relationships between genes and organs from Gene ORGANizer for MT-TQ Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • cardiovascular
  • digestive
  • endocrine
  • immune
  • integumentary
  • nervous
  • respiratory
  • skeletal muscle
  • urinary
Regions:
Head and neck:
  • brain
  • cerebellum
  • cranial nerve
  • ear
  • eye
  • eyelid
  • face
  • head
  • inner ear
Thorax:
  • diaphragm
  • esophagus
  • heart
  • heart valve
  • lung
Abdomen:
  • kidney
  • pancreas
  • stomach
General:
  • blood
  • blood vessel
  • peripheral nerve
  • peripheral nervous system
  • skin
  • spinal cord
  • white blood cell
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Evidence on tissue expression from TISSUES for MT-TQ Gene

Orthologs for MT-TQ Gene

Evolution for MT-TQ Gene

ENSEMBL:
Gene Tree for MT-TQ (if available)
TreeFam:
Gene Tree for MT-TQ (if available)
Alliance of Genome Resources:
Additional Orthologs for MT-TQ

No data available for Orthologs for MT-TQ Gene

Paralogs for MT-TQ Gene

No data available for Paralogs for MT-TQ Gene

Variants for MT-TQ Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MT-TQ Gene

SNP ID Clinical significance and condition Chr MT pos Variation AA Info Type
rs1556422854 Likely Benign: Juvenile myopathy, encephalopathy, lactic acidosis AND stroke 4,387(-) C/T
NC_012920.1(MT-CYB):m.4387C>T
rs1569483940 Benign: Juvenile myopathy, encephalopathy, lactic acidosis AND stroke 4,386(-) T/C
NC_012920.1(MT-CYB):m.4386T>C
rs1603219415 Uncertain Significance: Juvenile myopathy, encephalopathy, lactic acidosis AND stroke 4,339(-) G/A
NC_012920.1(MT-CYB):m.4339G>A
rs1603219416 Benign: Juvenile myopathy, encephalopathy, lactic acidosis AND stroke 4,340(-) A/G
NC_012920.1(MT-CYB):m.4340A>G
rs1603219418 Benign: Juvenile myopathy, encephalopathy, lactic acidosis AND stroke 4,350(-) C/T
NC_012920.1(MT-CYB):m.4350C>T

Additional Variant Information for MT-TQ Gene

Human Gene Mutation Database (HGMD)
MT-TQ
SNPedia medical, phenotypic, and genealogical associations of SNPs for
MT-TQ
Leiden Open Variation Database (LOVD)
MT-TQ

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , dbSNP identifiers (rs#s) for variants without ClinVar clinical significance , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MT-TQ Gene

Disorders for MT-TQ Gene

MalaCards: The human disease database

(11) MalaCards diseases for MT-TQ Gene - From: CVR, ORP, COP, and GCD

Additional Disease Information for MT-TQ

Open Targets Platform
Open Targets Platform
genes like me logo Genes that share disorders with MT-TQ: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MT-TQ Gene

Publications for MT-TQ Gene

  1. No association between Parkinson's disease and three polymorphisms in the eNOS, nNOS, and iNOS genes. (PMID: 17174475) Huerta C … Alvarez V (Neuroscience letters 2007) 3 40
  2. The European-specific mitochondrial cluster J/T could confer an increased risk of insulin-resistance and type 2 diabetes: an analysis of the m.4216T > C and m.4917A > G variants. (PMID: 16759180) Crispim D … Roisenberg I (Annals of human genetics 2006) 3 40
  3. Interpretation of mitochondrial tRNA variants. (PMID: 31965079) Wong LC … Craigen WJ (Genetics in medicine : official journal of the American College of Medical Genetics 2020) 72
  4. [Mitochondrial DNA mutation associated with hypertension in tRNA(Ile) and tRNA(Gln) genes]. (PMID: 25297595) Zhu C … Li Y (Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 2014) 3
  5. Role of taurine in the pathologies of MELAS and MERRF. (PMID: 23179085) Schaffer SW … Azuma J (Amino acids 2014) 72

Products for MT-TQ Gene

Sources for MT-TQ Gene