Aliases for MST1L Gene

Aliases for MST1L Gene

  • Macrophage Stimulating 1 Like 2 3 5
  • Macrophage Stimulating 1 (Hepatocyte Growth Factor-Like) Pseudogene 9 2 3
  • Putative Macrophage Stimulating 1-Like Protein 3 4
  • Macrophage Stimulating, Pseudogene 7 2 3
  • Macrophage Stimulating, Pseudogene 9 2 3
  • D1F15S1A 3 4
  • MST1P9 3 4
  • MSTP9 3 4
  • BRF-1 3 4
  • Putative Macrophage-Stimulating Protein MSTP9 3
  • Hepatocyte Growth Factor-Like Protein Homolog 4
  • Brain-Rescue-Factor-1 3
  • Brain Rescue Factor 1 4
  • MSPL-7 3
  • MSPL7 3
  • MSTP7 3

External Ids for MST1L Gene

Previous HGNC Symbols for MST1L Gene

  • MSTP7
  • MSTP9
  • MST1P9

Previous GeneCards Identifiers for MST1L Gene

  • GC01M017083

Summaries for MST1L Gene

GeneCards Summary for MST1L Gene

MST1L (Macrophage Stimulating 1 Like) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase activity.

Additional gene information for MST1L Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MST1L Gene

Genomics for MST1L Gene

GeneHancer (GH) Regulatory Elements for MST1L Gene

Promoters and enhancers for MST1L Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MST1L on UCSC Golden Path with GeneCards custom track

Genomic Locations for MST1L Gene

Genomic Locations for MST1L Gene
chr1:16,754,634-16,770,237
(GRCh38/hg38)
Size:
15,604 bases
Orientation:
Minus strand
chr1:17,081,401-17,096,732
(GRCh37/hg19)
Size:
15,332 bases
Orientation:
Minus strand

Genomic View for MST1L Gene

Genes around MST1L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MST1L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MST1L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MST1L Gene

Proteins for MST1L Gene

  • Protein details for MST1L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q2TV78-MST1L_HUMAN
    Recommended name:
    Putative macrophage stimulating 1-like protein
    Protein Accession:
    Q2TV78
    Secondary Accessions:
    • B7WPB1
    • Q13209

    Protein attributes for MST1L Gene

    Size:
    715 amino acids
    Molecular mass:
    79694 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAC35412.1; Type=Miscellaneous discrepancy; Note=Unlikely isoform. Aberrant splice sites.; Evidence={ECO:0000305};

    Alternative splice isoforms for MST1L Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MST1L Gene

Post-translational modifications for MST1L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MST1L Gene

REFSEQ proteins:

No data available for DME Specific Peptides for MST1L Gene

Domains & Families for MST1L Gene

Suggested Antigen Peptide Sequences for MST1L Gene

GenScript: Design optimal peptide antigens:
  • Hepatocyte growth factor-like protein homolog (MSTP9_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q2TV78

UniProtKB/Swiss-Prot:

MST1L_HUMAN :
  • Belongs to the peptidase S1 family. Plasminogen subfamily.
Family:
  • Belongs to the peptidase S1 family. Plasminogen subfamily.
genes like me logo Genes that share domains with MST1L: view

No data available for Gene Families for MST1L Gene

Function for MST1L Gene

Molecular function for MST1L Gene

GENATLAS Biochemistry:
macrocyte stimulating factor 1,like sequence

Phenotypes From GWAS Catalog for MST1L Gene

Gene Ontology (GO) - Molecular Function for MST1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004252 serine-type endopeptidase activity IBA 21873635
genes like me logo Genes that share ontologies with MST1L: view

Animal Model Products

CRISPR Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MST1L Gene

Localization for MST1L Gene

Subcellular locations from UniProtKB/Swiss-Prot for MST1L Gene

Secreted.

Gene Ontology (GO) - Cellular Components for MST1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with MST1L: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MST1L Gene

Pathways & Interactions for MST1L Gene

PathCards logo

SuperPathways for MST1L Gene

No Data Available

Interacting Proteins for MST1L Gene

Gene Ontology (GO) - Biological Process for MST1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006508 proteolysis IEA --
GO:0010758 regulation of macrophage chemotaxis IBA 21873635
GO:0033601 positive regulation of mammary gland epithelial cell proliferation IBA 21873635
genes like me logo Genes that share ontologies with MST1L: view

No data available for Pathways by source and SIGNOR curated interactions for MST1L Gene

Drugs & Compounds for MST1L Gene

No Compound Related Data Available

Transcripts for MST1L Gene

mRNA/cDNA for MST1L Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(6) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MST1L Gene

No ASD Table

Relevant External Links for MST1L Gene

GeneLoc Exon Structure for
MST1L
ECgene alternative splicing isoforms for
MST1L

Expression for MST1L Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MST1L Gene

mRNA differential expression in normal tissues according to GTEx for MST1L Gene

This gene is overexpressed in Liver (x15.0), Kidney - Cortex (x9.7), and Pancreas (x6.9).

Protein differential expression in normal tissues from HIPED for MST1L Gene

This gene is overexpressed in Serum (61.1) and Islet of Langerhans (7.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for MST1L Gene



Protein tissue co-expression partners for MST1L Gene

NURSA nuclear receptor signaling pathways regulating expression of MST1L Gene:

MST1L

SOURCE GeneReport for Unigene cluster for MST1L Gene:

Hs.655432

Evidence on tissue expression from TISSUES for MST1L Gene

  • Liver(4.1)
  • Nervous system(4)
genes like me logo Genes that share expression patterns with MST1L: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for MST1L Gene

Orthologs for MST1L Gene

Evolution for MST1L Gene

ENSEMBL:
Gene Tree for MST1L (if available)
TreeFam:
Gene Tree for MST1L (if available)

No data available for Orthologs for MST1L Gene

Paralogs for MST1L Gene

(24) SIMAP similar genes for MST1L Gene using alignment to 1 proteins:

  • MST1L_HUMAN
genes like me logo Genes that share paralogs with MST1L: view

No data available for Paralogs for MST1L Gene

Variants for MST1L Gene

Sequence variations from dbSNP and Humsavar for MST1L Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1006602305 -- 16,759,556(-) G/A/T coding_sequence_variant, missense_variant, synonymous_variant
rs1011474753 -- 16,766,284(-) T/G upstream_transcript_variant
rs1011508819 -- 16,763,628(-) G/A intron_variant
rs10159208 -- 16,757,073(-) G/A 3_prime_UTR_variant
rs1022276246 -- 16,763,681(-) T/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for MST1L Gene

Variant ID Type Subtype PubMed ID
dgv101n100 CNV gain 25217958
dgv164n54 CNV loss 21841781
dgv1e203 CNV gain+loss 21179565
dgv20n67 CNV gain 20364138
dgv21n67 CNV gain 20364138
dgv22n67 CNV gain 20364138
dgv39n100 CNV gain 25217958
dgv42n100 CNV loss 25217958
dgv45n100 CNV gain 25217958
dgv51n100 CNV loss 25217958
dgv52e59 CNV duplication 20981092
dgv52n100 CNV gain+loss 25217958
dgv53n100 CNV loss 25217958
dgv54n100 CNV gain 25217958
dgv55n100 CNV gain+loss 25217958
dgv62n100 CNV gain 25217958
dgv63n100 CNV gain 25217958
dgv65n100 CNV gain 25217958
dgv70n100 CNV gain+loss 25217958
dgv74n100 CNV gain 25217958
dgv75n100 CNV gain 25217958
dgv77n100 CNV loss 25217958
dgv78n100 CNV loss 25217958
dgv82n100 CNV gain+loss 25217958
dgv83n100 CNV loss 25217958
dgv85n100 CNV gain 25217958
dgv86n100 CNV gain 25217958
dgv87n100 CNV loss 25217958
dgv89n100 CNV gain+loss 25217958
dgv90n100 CNV gain 25217958
dgv91n100 CNV gain+loss 25217958
dgv92n100 CNV gain 25217958
dgv93n100 CNV gain 25217958
esv2758925 CNV gain+loss 17122850
esv29642 CNV gain+loss 19812545
esv29948 CNV loss 18421352
esv3372391 CNV duplication 20981092
esv33965 CNV gain+loss 17666407
esv3414600 CNV duplication 20981092
esv3430695 CNV duplication 20981092
esv3577752 CNV loss 25503493
esv3892414 CNV gain 25118596
nsv1004978 CNV gain+loss 25217958
nsv1009050 CNV loss 25217958
nsv1013011 CNV gain 25217958
nsv1075777 CNV duplication 25765185
nsv1115339 CNV duplication 24896259
nsv1116446 OTHER inversion 24896259
nsv1145756 CNV duplication 26484159
nsv1161242 CNV duplication 26073780
nsv1161259 CNV duplication 26073780
nsv3965 CNV insertion 18451855
nsv428421 CNV gain+loss 18775914
nsv436652 OTHER inversion 17901297
nsv437206 CNV loss 16327808
nsv545667 CNV loss 21841781
nsv7173 OTHER inversion 18451855
nsv821511 CNV duplication 20802225
nsv821743 CNV gain 20364138
nsv829625 CNV gain 20364138
nsv9324 CNV gain+loss 18304495
nsv945798 CNV duplication 23825009
nsv945799 CNV duplication 23825009
nsv954849 CNV duplication 24416366

Additional Variant Information for MST1L Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MST1L

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MST1L Gene

Disorders for MST1L Gene

Additional Disease Information for MST1L

No disorders were found for MST1L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MST1L Gene

Publications for MST1L Gene

  1. Structure of the human D1F15S1A locus: a chromosome 1 locus with 97% identity to the chromosome 3 gene coding for hepatocyte growth factor-like protein. (PMID: 10728827) Degen SJ … Carritt B (DNA sequence : the journal of DNA sequencing and mapping 1998) 2 3 4 56
  2. Identification of minimal eukaryotic introns through GeneBase, a user-friendly tool for parsing the NCBI Gene databank. (PMID: 26581719) Piovesan A … Pelleri MC (DNA research : an international journal for rapid publication of reports on genes and genomes 2015) 3 56
  3. The GENCODE pseudogene resource. (PMID: 22951037) Pei B … Gerstein MB (Genome biology 2012) 3 56
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3 56
  5. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 4 56

Products for MST1L Gene

Sources for MST1L Gene