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Aliases for MST1L Gene

Aliases for MST1L Gene

  • Macrophage Stimulating 1 Like 2 3 5
  • Macrophage Stimulating 1 (Hepatocyte Growth Factor-Like) Pseudogene 9 2 3
  • Macrophage Stimulating, Pseudogene 7 2 3
  • Macrophage Stimulating, Pseudogene 9 2 3
  • D1F15S1A 3 4
  • MST1P9 3 4
  • BRF-1 3 4
  • MSTP9 3 4
  • Putative Macrophage Stimulating 1-Like Protein 3
  • Putative Macrophage-Stimulating Protein MSTP9 3
  • Hepatocyte Growth Factor-Like Protein Homolog 4
  • Brain-Rescue-Factor-1 3
  • Brain Rescue Factor 1 4
  • MSPL-7 3
  • MSPL7 3
  • MSTP7 3

External Ids for MST1L Gene

Previous HGNC Symbols for MST1L Gene

  • MSTP7
  • MSTP9
  • MST1P9

Previous GeneCards Identifiers for MST1L Gene

  • GC01M017083

Summaries for MST1L Gene

GeneCards Summary for MST1L Gene

MST1L (Macrophage Stimulating 1 Like) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase activity.

Additional gene information for MST1L Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MST1L Gene

Genomics for MST1L Gene

GeneHancer (GH) Regulatory Elements for MST1L Gene

Promoters and enhancers for MST1L Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01I016770 Enhancer 0.5 ENCODE dbSUPER 550.8 -0.3 -344 0.2 ZSCAN21 MST1L CROCC ENSG00000223643
GH01I016960 Enhancer 1.3 Ensembl ENCODE dbSUPER 19.3 -190.8 -190762 1.4 ATF1 ARNT ARID4B SIN3A DMAP1 ZNF48 ZNF121 ZNF143 ATF7 RUNX3 MST1L LOC105376805 CROCC PIR50545 PIR44310
GH01I016678 Enhancer 1.2 ENCODE dbSUPER 16.1 +92.0 91976 0.4 MLX ARNT ARID4B SIN3A ZNF2 ZNF766 ZNF213 FOS KLF13 SP3 GC01M016679 CROCC MST1L SPEN TRE-TTC3-1 CROCCP3 LINC01772 FLJ37453 FAM231AP
GH01I016676 Enhancer 1.2 Ensembl ENCODE dbSUPER 15.9 +93.2 93156 0.7 BATF IRF4 SCRT2 ATF7 IKZF2 RUNX3 ZNF362 CBFB JUNB SP1 GC01M016679 MST1L TRE-TTC3-1 FAM231AP
GH01I016706 Enhancer 1.4 Ensembl ENCODE dbSUPER 6.1 +63.0 63022 2.2 ATF1 ZNF133 SIN3A GLI4 ZNF2 ZBTB7B ZNF48 ZNF121 GLIS2 ZNF213 ZBTB17 CROCC CROCCP3 LINC01772 SPEN NECAP2 RCC2 MST1L ESPNP CROCCP4
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MST1L on UCSC Golden Path with GeneCards custom track

Genomic Locations for MST1L Gene

Genomic Locations for MST1L Gene
15,604 bases
Minus strand

Genomic View for MST1L Gene

Genes around MST1L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MST1L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MST1L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MST1L Gene

Proteins for MST1L Gene

  • Protein details for MST1L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative macrophage stimulating 1-like protein
    Protein Accession:
    Secondary Accessions:
    • B7WPB1
    • Q13209

    Protein attributes for MST1L Gene

    715 amino acids
    Molecular mass:
    79694 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAC35412.1; Type=Miscellaneous discrepancy; Note=Unlikely isoform. Aberrant splice sites.; Evidence={ECO:0000305};

    Alternative splice isoforms for MST1L Gene


neXtProt entry for MST1L Gene

Post-translational modifications for MST1L Gene

No Post-translational modifications

Other Protein References for MST1L Gene

REFSEQ proteins:

No data available for DME Specific Peptides for MST1L Gene

Domains & Families for MST1L Gene

Suggested Antigen Peptide Sequences for MST1L Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the peptidase S1 family. Plasminogen subfamily.
  • Belongs to the peptidase S1 family. Plasminogen subfamily.
genes like me logo Genes that share domains with MST1L: view

No data available for Gene Families for MST1L Gene

Function for MST1L Gene

Molecular function for MST1L Gene

GENATLAS Biochemistry:
macrocyte stimulating factor 1,like sequence

Gene Ontology (GO) - Molecular Function for MST1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004252 serine-type endopeptidase activity IEA --
genes like me logo Genes that share ontologies with MST1L: view

Clone Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MST1L Gene

Localization for MST1L Gene

Subcellular locations from UniProtKB/Swiss-Prot for MST1L Gene


Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MST1L gene
Compartment Confidence
extracellular 4
plasma membrane 1
mitochondrion 1
peroxisome 1
nucleus 1
cytosol 1

Gene Ontology (GO) - Cellular Components for MST1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IBA --
genes like me logo Genes that share ontologies with MST1L: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for MST1L Gene

Pathways & Interactions for MST1L Gene

SuperPathways for MST1L Gene

No Data Available

Interacting Proteins for MST1L Gene

Selected Interacting proteins: Q2TV78-MST1L_HUMAN for MST1L Gene via IID

Gene Ontology (GO) - Biological Process for MST1L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006508 proteolysis IEA --
genes like me logo Genes that share ontologies with MST1L: view

No data available for Pathways by source and SIGNOR curated interactions for MST1L Gene

Drugs & Compounds for MST1L Gene

No Compound Related Data Available

Transcripts for MST1L Gene

mRNA/cDNA for MST1L Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MST1L Gene

Macrophage stimulating 1-like:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MST1L Gene

No ASD Table

Relevant External Links for MST1L Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MST1L Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MST1L Gene

mRNA differential expression in normal tissues according to GTEx for MST1L Gene

This gene is overexpressed in Liver (x15.0), Kidney - Cortex (x9.7), and Pancreas (x6.9).

Protein differential expression in normal tissues from HIPED for MST1L Gene

This gene is overexpressed in Serum (61.1) and Islet of Langerhans (7.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for MST1L Gene

Protein tissue co-expression partners for MST1L Gene

NURSA nuclear receptor signaling pathways regulating expression of MST1L Gene:


SOURCE GeneReport for Unigene cluster for MST1L Gene:


Evidence on tissue expression from TISSUES for MST1L Gene

  • Liver(4.1)
  • Nervous system(4)
genes like me logo Genes that share expression patterns with MST1L: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for MST1L Gene

Orthologs for MST1L Gene

Evolution for MST1L Gene

Gene Tree for MST1L (if available)
Gene Tree for MST1L (if available)

No data available for Orthologs for MST1L Gene

Paralogs for MST1L Gene

(24) SIMAP similar genes for MST1L Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with MST1L: view

No data available for Paralogs for MST1L Gene

Variants for MST1L Gene

Sequence variations from dbSNP and Humsavar for MST1L Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1006602305 -- 16,759,556(-) G/A/T coding_sequence_variant, missense_variant, synonymous_variant
rs1011474753 -- 16,766,284(-) T/G upstream_transcript_variant
rs1011508819 -- 16,763,628(-) G/A intron_variant
rs10159208 -- 16,757,073(-) G/A 3_prime_UTR_variant
rs1022276246 -- 16,763,681(-) T/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for MST1L Gene

Variant ID Type Subtype PubMed ID
nsv954849 CNV duplication 24416366
nsv945799 CNV duplication 23825009
nsv945798 CNV duplication 23825009
nsv9324 CNV gain+loss 18304495
nsv829625 CNV gain 20364138
nsv821743 CNV gain 20364138
nsv821511 CNV duplication 20802225
nsv7173 OTHER inversion 18451855
nsv545667 CNV loss 21841781
nsv437206 CNV loss 16327808
nsv436652 OTHER inversion 17901297
nsv428421 CNV gain+loss 18775914
nsv3965 CNV insertion 18451855
nsv1161259 CNV duplication 26073780
nsv1161242 CNV duplication 26073780
nsv1145756 CNV duplication 26484159
nsv1116446 OTHER inversion 24896259
nsv1115339 CNV duplication 24896259
nsv1075777 CNV duplication 25765185
nsv1013011 CNV gain 25217958
nsv1009050 CNV loss 25217958
nsv1004978 CNV gain+loss 25217958
esv3892414 CNV gain 25118596
esv3577752 CNV loss 25503493
esv3430695 CNV duplication 20981092
esv3414600 CNV duplication 20981092
esv33965 CNV gain+loss 17666407
esv3372391 CNV duplication 20981092
esv29948 CNV loss 18421352
esv29642 CNV gain+loss 19812545
esv2758925 CNV gain+loss 17122850
dgv93n100 CNV gain 25217958
dgv92n100 CNV gain 25217958
dgv91n100 CNV gain+loss 25217958
dgv90n100 CNV gain 25217958
dgv89n100 CNV gain+loss 25217958
dgv87n100 CNV loss 25217958
dgv86n100 CNV gain 25217958
dgv85n100 CNV gain 25217958
dgv83n100 CNV loss 25217958
dgv82n100 CNV gain+loss 25217958
dgv78n100 CNV loss 25217958
dgv77n100 CNV loss 25217958
dgv75n100 CNV gain 25217958
dgv74n100 CNV gain 25217958
dgv70n100 CNV gain+loss 25217958
dgv65n100 CNV gain 25217958
dgv63n100 CNV gain 25217958
dgv62n100 CNV gain 25217958
dgv55n100 CNV gain+loss 25217958
dgv54n100 CNV gain 25217958
dgv53n100 CNV loss 25217958
dgv52n100 CNV gain+loss 25217958
dgv52e59 CNV duplication 20981092
dgv51n100 CNV loss 25217958
dgv45n100 CNV gain 25217958
dgv42n100 CNV loss 25217958
dgv39n100 CNV gain 25217958
dgv22n67 CNV gain 20364138
dgv21n67 CNV gain 20364138
dgv20n67 CNV gain 20364138
dgv1e203 CNV gain+loss 21179565
dgv164n54 CNV loss 21841781
dgv101n100 CNV gain 25217958

Additional Variant Information for MST1L Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MST1L Gene

Disorders for MST1L Gene

Additional Disease Information for MST1L

No disorders were found for MST1L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MST1L Gene

Publications for MST1L Gene

  1. Structure of the human D1F15S1A locus: a chromosome 1 locus with 97% identity to the chromosome 3 gene coding for hepatocyte growth factor-like protein. (PMID: 10728827) Degen SJ … Carritt B (DNA sequence : the journal of DNA sequencing and mapping 1998) 2 3 4 58
  2. Identification of minimal eukaryotic introns through GeneBase, a user-friendly tool for parsing the NCBI Gene databank. (PMID: 26581719) Piovesan A … Pelleri MC (DNA research : an international journal for rapid publication of reports on genes and genomes 2015) 3 58
  3. The GENCODE pseudogene resource. (PMID: 22951037) Pei B … Gerstein MB (Genome biology 2012) 3 58
  4. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 4 58
  5. Multiple MSP pseudogenes in a local repeat cluster on 1p36.2: An expanding genomic graveyard? (PMID: 10585770) van der Drift P … Versteeg R (Genomics 1999) 3 58

Products for MST1L Gene

Sources for MST1L Gene

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