Aliases for MSRB2 Gene
External Ids for MSRB2 Gene
Previous HGNC Symbols for MSRB2 Gene
Previous GeneCards Identifiers for MSRB2 Gene
GeneCards Summary for MSRB2 Gene
MSRB2 (Methionine Sulfoxide Reductase B2) is a Protein Coding gene. Among its related pathways are Protein repair and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and peptide-methionine (R)-S-oxide reductase activity. An important paralog of this gene is MSRB3.
UniProtKB/Swiss-Prot for MSRB2 Gene
Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance.