Aliases for MSRA Gene
External Ids for MSRA Gene
Previous GeneCards Identifiers for MSRA Gene
This gene encodes a ubiquitous and highly conserved protein that carries out the enzymatic reduction of methionine sulfoxide to methionine. Human and animal studies have shown the highest levels of expression in kidney and nervous tissue. The protein functions in the repair of oxidatively damaged proteins to restore biological activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
GeneCards Summary for MSRA Gene
MSRA (Methionine Sulfoxide Reductase A) is a Protein Coding gene. Diseases associated with MSRA include Mycobacterium Abscessus and Intestinal Obstruction. Among its related pathways are Protein repair and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include peptide-methionine (S)-S-oxide reductase activity. An important paralog of this gene is MSRB3.
UniProtKB/Swiss-Prot Summary for MSRA Gene
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.