Aliases for MSN Gene
External Ids for MSN Gene
Previous GeneCards Identifiers for MSN Gene
Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. [provided by RefSeq, Jul 2008]
GeneCards Summary for MSN Gene
MSN (Moesin) is a Protein Coding gene. Diseases associated with MSN include Immunodeficiency 50 and Neurofibromatosis, Type Ii. Among its related pathways are RhoA signaling pathway and L1CAM interactions. Gene Ontology (GO) annotations related to this gene include protein kinase binding and actin binding. An important paralog of this gene is RDX.
UniProtKB/Swiss-Prot for MSN Gene
Probably involved in connections of major cytoskeletal structures to the plasma membrane. May inhibit herpes simplex virus 1 infection at an early stage. Plays a role in regulating the proliferation, migration, and adhesion of human lymphoid cells and participates in immunologic synapse formation (PubMed:27405666).