Aliases for MSI2 Gene
External Ids for MSI2 Gene
Previous GeneCards Identifiers for MSI2 Gene
This gene encodes an RNA-binding protein that is a member of the Musashi protein family. The encoded protein is transcriptional regulator that targets genes involved in development and cell cycle regulation. Mutations in this gene are associated with poor prognosis in certain types of cancers. This gene has also been shown to be rearranged in certain cancer cells. [provided by RefSeq, Apr 2016]
GeneCards Summary for MSI2 Gene
MSI2 (Musashi RNA Binding Protein 2) is a Protein Coding gene. Diseases associated with MSI2 include B-Cell Adult Acute Lymphocytic Leukemia. Among its related pathways are mRNA surveillance pathway and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and nucleotide binding. An important paralog of this gene is MSI1.
UniProtKB/Swiss-Prot Summary for MSI2 Gene
RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).