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This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is locate... See more...
Aliases for MSI1 Gene
Aliases for MSI1 Gene
External Ids for MSI1 Gene
- HGNC: 7330
- Entrez Gene: 4440
- Ensembl: ENSG00000135097
- OMIM: 603328
- UniProtKB: O43347
Previous GeneCards Identifiers for MSI1 Gene
- GC12M119653
- GC12M120306
- GC12M120561
- GC12M119191
- GC12M119241
- GC12M119263
- GC12M120779
- GC12M117787
Summaries for MSI1 Gene
-
This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13. [provided by RefSeq, Jul 2008]
GeneCards Summary for MSI1 Gene
MSI1 (Musashi RNA Binding Protein 1) is a Protein Coding gene. Diseases associated with MSI1 include Gallbladder Adenocarcinoma and Deafness, Autosomal Dominant 64. Among its related pathways are Neuroscience and Embryonic and Induced Pluripotent Stem Cells and Lineage-specific Markers. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and RNA binding. An important paralog of this gene is MSI2.
UniProtKB/Swiss-Prot Summary for MSI1 Gene
-
RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-[GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).
Additional gene information for MSI1 Gene
- HGNC(7330)
- Entrez Gene(4440)
- Ensembl(ENSG00000135097)
- OMIM(603328)
- UniProtKB(O43347)
- Open Targets Platform(ENSG00000135097)
- Search for MSI1 at DataMed
- Search for MSI1 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MSI1 Gene
Genomics for MSI1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for MSI1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around MSI1 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for MSI1
- Top Transcription factor binding sites by QIAGEN in the MSI1 gene promoter:
-
- E2F-1
- E2F-2
- E2F-3a
- E2F-4
- E2F-5
- p53
- Sox9
- Zic3
Genomic Locations for MSI1 Gene
Genomic Locations for MSI1 Gene
- chr12:120,339,662-120,369,174
- (GRCh38/hg38)
- Size:
- 29,513 bases
- Orientation:
- Minus strand
- chr12:120,779,133-120,806,983
- (GRCh37/hg19)
- Size:
- 27,851 bases
- Orientation:
- Minus strand
Genomic View for MSI1 Gene
Genes around MSI1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12q24.31 by HGNC
- 12q24.31 by Entrez Gene
- 12q24.31 by Ensembl
MSI1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MSI1 Gene
Proteins for MSI1 Gene
-
Protein details for MSI1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O43347-MSI1H_HUMAN
- Recommended name:
- RNA-binding protein Musashi homolog 1
- Protein Accession:
- O43347
- Q96PU0
- Q96PU1
- Q96PU2
- Q96PU3
Protein attributes for MSI1 Gene
- Size:
- 362 amino acids
- Molecular mass:
- 39125 Da
- Quaternary structure:
- No Data Available
Protein Expression for MSI1 Gene
Post-translational modifications for MSI1 Gene
Other Protein References for MSI1 Gene
Antibody Products
- LifeSpan BioSciences MSI1 / Musashi 1 Monoclonal Antibody and MSI1 / Musashi 1 Antibody
- G Biosciences Immunotag™ MSI1 Antibody
- GeneTex Anti-Musashi 1 antibody [N3C3]
- NSJ Bioreagents MSI1 Antibody / Musashi 1 (Rabbit Monoclonal)
-
Custom Antibody ServicesOriGene Antibodies for MSI1
- AM06590SU-N
- AM20917PU-N
- AP52759PU-N
- CF502198
- CF502252
- CF502253
- CF502254
- CF502273
- CF502311
- CF502370
- CF502420
- CF506357
- CF506364
- TA336268
- TA347006
- TA351894
- TA502198
- TA502198S
- TA502252
- TA502252S
- TA502253
- TA502253S
- TA502254
- TA502254S
- TA502273
- TA502273S
- TA502311
- TA502311S
- TA502370
- TA502370S
- TA502420
- TA502420S
- TA506357
- TA506357S
- TA506364
- TA506364S
- UM500092
- UM500092CF
- UM570092
- Novus Biologicals Antibodies for MSI1
-
Abcam antibodies for MSI1
- Invitrogen Antibodies for MSI1 (AFLGC-MSI1)
-
Santa Cruz Biotechnology (SCBT) Antibodies for MSI1
- Sino Biological Antibodies for MSI1
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for MSI1
- Origene Custom Protein Services for MSI1
-
Abcam proteins for MSI1
Assay Products
- antibodies-online: Show 3 available MSI1 Elisa Kits ranked by validation data
- Compare Top MSI1 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for MSI1 Gene
Domains & Families for MSI1 Gene
Gene Families for MSI1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for MSI1 Gene
- InterPro:
- Blocks:
-
- RNA-binding region RNP-1 (RNA recognition motif)
- ProtoNet:
Suggested Antigen Peptide Sequences for MSI1 Gene
- GenScript: Design optimal peptide antigens:
-
- RNA-binding protein Musashi homolog 1 (MSI1H_HUMAN)
Graphical View of Domain Structure for InterPro Entry
O43347UniProtKB/Swiss-Prot:
MSI1H_HUMAN :- The first RNA recognition motif binds more strongly to RNA compared to the second one.
- Belongs to the Musashi family.
- Domain:
-
- The first RNA recognition motif binds more strongly to RNA compared to the second one.
- Family:
-
- Belongs to the Musashi family.
Function for MSI1 Gene
Molecular function for MSI1 Gene
- UniProtKB/Swiss-Prot Function:
- RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-[GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).
- GENATLAS Biochemistry:
- Musahi (Drosophila) homolog 1,39kDa,neural RNA-binding protein putatively expressed in CNS stem cells and neural progenitor cells,with an alternatively spliced isoform
Phenotypes From GWAS Catalog for MSI1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003676 | nucleic acid binding | IEA | -- |
| GO:0003723 | RNA binding | IEA,HDA | 22681889 |
| GO:0003727 | single-stranded RNA binding | IEA | -- |
| GO:0005515 | protein binding | IPI | 30367664 |
| GO:0008266 | poly(U) RNA binding | IEA | -- |
Phenotypes for MSI1 Gene
- MGI mutant phenotypes for MSI1:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for MSI1:
Animal Models for MSI1 Gene
- MGI Knock Outs for MSI1:
-
- Msi1 Msi1<tm1Okn>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for MSI1 - Select products 50% OFF >
- * MSI1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
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-
OriGene CRISPR knockouts for MSI1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MSI1
-
Santa Cruz Biotechnology (SCBT) CRISPR for MSI1
miRNA for MSI1 Gene
- miRTarBase miRNAs that target MSI1
-
- hsa-miR-197-3p (MIRT048066)
- hsa-let-7b-5p (MIRT052295)
- hsa-miR-4697-5p (MIRT491086)
- hsa-miR-4488 (MIRT491087)
- hsa-miR-6825-5p (MIRT491088)
- hsa-miR-1237-5p (MIRT491089)
- hsa-miR-6883-5p (MIRT491090)
- hsa-miR-6785-5p (MIRT491091)
- hsa-miR-4728-5p (MIRT491092)
- hsa-miR-604 (MIRT491093)
- hsa-miR-149-3p (MIRT491094)
- hsa-miR-4467 (MIRT491095)
- hsa-miR-8072 (MIRT491096)
- hsa-miR-3960 (MIRT491097)
- hsa-miR-6722-3p (MIRT491098)
- hsa-miR-1909-3p (MIRT491099)
- hsa-miR-6836-5p (MIRT491100)
- hsa-miR-6132 (MIRT491101)
- hsa-miR-6805-5p (MIRT491102)
- hsa-miR-1205 (MIRT491103)
- hsa-miR-3196 (MIRT500166)
- hsa-miR-6816-5p (MIRT500167)
- hsa-miR-3180-3p (MIRT500168)
- hsa-miR-3180 (MIRT500169)
- hsa-miR-5572 (MIRT649984)
- hsa-miR-4260 (MIRT649985)
- hsa-miR-450a-2-3p (MIRT649986)
- hsa-miR-6763-5p (MIRT649987)
- hsa-miR-6857-5p (MIRT649988)
- hsa-miR-6810-5p (MIRT649989)
- hsa-miR-3150a-3p (MIRT649990)
- hsa-miR-2110 (MIRT649991)
- hsa-miR-939-5p (MIRT649992)
- hsa-miR-1343-5p (MIRT649993)
- hsa-miR-3175 (MIRT649994)
- hsa-miR-4719 (MIRT649995)
- hsa-miR-502-3p (MIRT649996)
- hsa-miR-501-3p (MIRT649997)
- hsa-miR-137 (MIRT733355)
- hsa-miR-330-3p (MIRT733660)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MSI1
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- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MSI1
Clone Products
- Applied Biological Materials (abm): Clones for MSI1 - Select products 50% OFF >
- * MSI1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for MSI1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MSI1
Cell Line Products
-
Horizon Cell Lines for MSI1
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for MSI1 Gene
Localization for MSI1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for MSI1 Gene
- Cytoplasm. Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 3 |
| plasma membrane | 2 |
| extracellular | 2 |
| cytoskeleton | 2 |
| mitochondrion | 2 |
| endoplasmic reticulum | 1 |
- Cytosol (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IBA | -- |
| GO:0005737 | cytoplasm | IBA | 21873635 |
| GO:0005844 | polysome | IBA | 21873635 |
| GO:1990904 | ribonucleoprotein complex | IBA | -- |
Pathways & Interactions for MSI1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Neuroscience | ||
| 2 | Wnt / Hedgehog / Notch | ||
| 3 | mRNA surveillance pathway | ||
| 4 | Embryonic and Induced Pluripotent Stem Cells and Lineage-specific Markers | ||
| 5 | Neural Stem Cells and Lineage-specific Markers | ||
Pathways by source for MSI1 Gene
1 KEGG pathway for MSI1 Gene
2 R&D Systems pathways for MSI1 Gene
2 Cell Signaling Technology pathways for MSI1 Gene
Interacting Proteins for MSI1 Gene
Selected Interacting proteins:
O43347-MSI1H_HUMAN
ENSP00000257552
for MSI1 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for MSI1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007399 | nervous system development | TAS | 9790759 |
| GO:0051252 | regulation of RNA metabolic process | IBA | -- |
Transcripts for MSI1 Gene
mRNA/cDNA for MSI1 Gene
- 1 REFSEQ mRNAs :
- 8 NCBI additional mRNA sequence :
- 3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000257552 2959 nts (view in UCSC)
- ENST00000546622 422 nts (view in UCSC)
- ENST00000546985 698 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for MSI1 - Select products 50% OFF >
- * MSI1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for MSI1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MSI1
-
Santa Cruz Biotechnology (SCBT) CRISPR for MSI1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MSI1
- Browse OriGene Inhibitory RNA Products For MSI1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MSI1
Clone Products
- Applied Biological Materials (abm): Clones for MSI1 - Select products 50% OFF >
- * MSI1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for MSI1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MSI1
Relevant External Links for MSI1 Gene
- GeneLoc Exon Structure for
- MSI1
Expression for MSI1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Epiblast (Early Embryonic Tissues)
- Intraembryonic Epiblast Cells Epiblast
- Spinal Cord (Nervous System)
- Heart (Cardiovascular System)
- Neural Ectoderm (Nervous System)
- NULL (Uncategorized)
-
Eye (Sensory Organs)
mRNA differential expression in normal tissues according to GTEx for MSI1 Gene
This gene is overexpressed in Testis (x6.1) and Pituitary (x4.9).
This gene is overexpressed in Retina (47.3) and Fetal Brain (13.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for MSI1 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MSI1
SOURCE GeneReport for Unigene cluster for MSI1 Gene:
Hs.158311mRNA Expression by UniProt/SwissProt for MSI1 Gene:
O43347-MSI1H_HUMAN
Tissue specificity:
Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines.
Evidence on tissue expression from TISSUES for MSI1 Gene
- Nervous system(4.5)
- Intestine(2.8)
- Stomach(2.3)
- Lung(2.2)
- Skin(2.2)
- Heart(2.1)
- Liver(2.1)
- Blood(2.1)
- Muscle(2.1)
- Kidney(2)
- Pancreas(2)
Primer Products
-
OriGene qPCR primer pairs for MSI1
-
OriGene qPCR primer pairs and template standards for MSI1
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for MSI1 Gene
Orthologs for MSI1 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | MSI1 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | MSI1 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | MSI1 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Msi1 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Msi1 30 17 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | MSI1 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | MSI1 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | MSI1 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | MSI1 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | msi1 30 |
|
||
| Str.3045 30 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.836 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | msi1 30 31 |
|
OneToMany | |
| MSI1 (2 of 2) 31 |
|
OneToMany | |||
| Fruit Fly (Drosophila melanogaster) |
Insecta | msi 32 |
|
|
|
| sqd 32 |
|
|
|||
| Rbp6 31 |
|
OneToMany | |||
| Worm (Caenorhabditis elegans) |
Secernentea | msi-1 31 32 |
|
OneToMany | |
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | HRP1 33 |
|
|
|
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
- Species where no ortholog for MSI1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for MSI1 Gene
- ENSEMBL:
- Gene Tree for MSI1 (if available)
- TreeFam:
- Gene Tree for MSI1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for MSI1: view image
Paralogs for MSI1 Gene
Paralogs for MSI1 Gene
- MSI2 5
- HNRNPA3 5
- HNRNPA1L2 5
- HNRNPA1 5
- HNRNPA2B1 5
- DAZAP1 5
- HNRNPAB 5
- HNRNPD 5
- HNRNPDL 5
- HNRNPA0 5
- HNRNPA1P48 5
- RBMX 5
- RBMXL1 5
- RBMXL2 5
- RBMXL3 5
- RBMY1E 5
- TIAL1 5
- RBMY1A1 5
- RBMY1B 5
- RBMY1D 5
- RBMY1F 5
- RBMY1J 5
- RBM19 5
- TIA1 5
- RBM47 5
- A1CF 5
- RBM39 5
- RBM46 5
- NCL 5
- CIRBP 5
- RBM4B 5
- RBM4 5
- RBM3 5
- RBM23 5
- RBM14-RBM4 5
- TRNAU1AP 5
- DND1 5
(13) SIMAP similar genes for MSI1 Gene using alignment to 2 proteins:
- MSI1H_HUMAN
- H0YHB7_HUMAN
Variants for MSI1 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MSI1 Gene
| SNP ID | Clinical significance and condition | Chr 12 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 721285 | Likely Benign: not provided | 120,357,901(-) | A/G | INTRON_VARIANT | |
| 741505 | Benign: not provided | 120,368,059(-) | C/G | SYNONYMOUS_VARIANT | |
| VAR_035485 | A breast cancer sample | p.Glu160Gln |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv24462 | CNV | gain | 19812545 |
| esv3549883 | CNV | deletion | 23714750 |
| nsv1071059 | CNV | deletion | 25765185 |
| nsv1110897 | OTHER | inversion | 24896259 |
| nsv1131047 | CNV | deletion | 24896259 |
| nsv560437 | CNV | loss | 21841781 |
Residual Variation Intolerance Score:
28.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.36;
8.03% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for MSI1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MSI1
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MSI1 Gene
Disorders for MSI1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| gallbladder adenocarcinoma |
|
|
| deafness, autosomal dominant 64 |
|
|
| brain cancer |
|
|
| gliosarcoma |
|
|
| medulloblastoma |
|
|
Search MSI1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for MSI1
No data available for UniProtKB/Swiss-Prot and Genatlas for MSI1 Gene
Publications for MSI1 Gene
- The human Musashi homolog 1 (MSI1) gene encoding the homologue of Musashi/Nrp-1, a neural RNA-binding protein putatively expressed in CNS stem cells and neural progenitor cells. (PMID: 9790759) Good P … Okano H (Genomics 1998) 2 3 4
- Musashi-1 suppresses expression of Paneth cell-specific genes in human intestinal epithelial cells. (PMID: 19214660) Murayama M … Watanabe M (Journal of gastroenterology 2009) 3 23
- Stem-cell-abundant proteins Nanog, Nucleostemin and Musashi1 are highly expressed in malignant cervical epithelial cells. (PMID: 18419830) Ye F … Chen H (BMC cancer 2008) 3 23
- Musashi1 modulates cell proliferation genes in the medulloblastoma cell line Daoy. (PMID: 18826648) Sanchez-Diaz PC … Penalva LO (BMC cancer 2008) 3 23
- The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer SE … Baylor College of Medicine Human Genome Sequencing Center Sequence Production Team (Nature 2006) 3 4
ExternalLinks
Products for MSI1 Gene
- Custom Antibody ServicesOriGene Antibodies for MSI1
- AM06590SU-N
- AM20917PU-N
- AP52759PU-N
- CF502198
- CF502252
- CF502253
- CF502254
- CF502273
- CF502311
- CF502370
- CF502420
- CF506357
- CF506364
- TA336268
- TA347006
- TA351894
- TA502198
- TA502198S
- TA502252
- TA502252S
- TA502253
- TA502253S
- TA502254
- TA502254S
- TA502273
- TA502273S
- TA502311
- TA502311S
- TA502370
- TA502370S
- TA502420
- TA502420S
- TA506357
- TA506357S
- TA506364
- TA506364S
- UM500092
- UM500092CF
- UM570092
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for MSI1
- Origene Custom Protein Services for MSI1
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MSI1
- Browse OriGene Inhibitory RNA Products For MSI1
- OriGene qPCR primer pairs for MSI1
- OriGene qPCR primer pairs and template standards for MSI1
- OriGene CRISPR knockouts for MSI1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For MSI1
- Sino Biological Human cDNA Clone for MSI1
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- Sino Biological Antibodies for MSI1
- Browse Sino Biological Assays
- Browse Antibodies
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- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for MSI1
- Novus Biologicals proteins and lysates for MSI1
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- Abcam antibodies for MSI1
- Abcam proteins for MSI1
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- Browse Primary Antibodies
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- Invitrogen Antibodies for MSI1 (AFLGC-MSI1)
- VectorBuilder Custom and pre-made DNA vectors for MSI1 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for MSI1 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for MSI1 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for MSI1 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for MSI1
- antibodies-online: Show 44 available MSI1 Antibodies ranked by validation data
- Compare Top MSI1 Antibodies
- antibodies-online: Show 3 available MSI1 Elisa Kits ranked by validation data
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- Quality Products:
- antibodies-online: Show 5 available MSI1 Proteins ranked by validation data
- Compare Top MSI1 Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for MSI1
- Search Santa Cruz Biotechnology (SCBT) for MSI1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for MSI1
- Horizon Cell Lines for MSI1
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MSI1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MSI1
- Search GeneCopoeia for miRNA 3'UTR Target clone products for MSI1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MSI1
Sources for MSI1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB