Aliases for MS4A12 Gene
External Ids for MS4A12 Gene
Previous GeneCards Identifiers for MS4A12 Gene
The protein encoded by this gene is a cell surface protein found primarily in the apical membrane of colonocytes. Silencing of this gene in colon cancer cells inhibits the proliferation, cell motility, and chemotactic invasion of cells. This gene is part of a cluster of similar genes found on chromosome 11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
GeneCards Summary for MS4A12 Gene
MS4A12 (Membrane Spanning 4-Domains A12) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include store-operated calcium channel activity. An important paralog of this gene is MS4A8.
UniProtKB/Swiss-Prot Summary for MS4A12 Gene
May be involved in signal transduction as a component of a multimeric receptor complex.