Aliases for MRS2 Gene
Aliases for MRS2 Gene
- MRS2, Magnesium Transporter 2 3 5
- MRS2-Like Protein 3 4
- MRS2L 3 4
- HPT 3 4
- MRS2 Magnesium Homeostasis Factor Homolog (S. Cerevisiae) 2
- MRS2-Like, Magnesium Homeostasis Factor (S. Cerevisiae) 2
- Magnesium Transporter MRS2 Homolog, Mitochondrial 3
- MRS2-Like, Magnesium Homeostasis Factor 3
- Putative Magnesium Transporter 3
External Ids for MRS2 Gene
- HGNC: 13785
- Entrez Gene: 57380
- Ensembl: ENSG00000124532
- UniProtKB: Q9HD23
Previous HGNC Symbols for MRS2 Gene
- MRS2L
Previous GeneCards Identifiers for MRS2 Gene
- GC06P024512
- GC06P024403
- GC06P024352
Summaries for MRS2 Gene
GeneCards Summary for MRS2 Gene
MRS2 (MRS2, Magnesium Transporter) is a Protein Coding gene. Diseases associated with MRS2 include Basilar Artery Occlusion. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Miscellaneous transport and binding events. Gene Ontology (GO) annotations related to this gene include magnesium ion transmembrane transporter activity.
UniProtKB/Swiss-Prot for MRS2 Gene
-
Magnesium transporter that mediates the influx of magnesium into the mitochondrial matrix (PubMed:11401429, PubMed:18384665). Required for normal expression of the mitochondrial respiratory complex I subunits (PubMed:18384665).
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MRS2 Gene
Genomics for MRS2 Gene
GeneHancer (GH) Regulatory Elements for MRS2 Gene
Promoters and enhancers for MRS2 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH06I024399 | Promoter/Enhancer | 2.3 | EPDnew Ensembl ENCODE | 588.4 | -1.0 | -975 | 5.3 | PKNOX1 SMAD1 FOXA2 MLX ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 | MRS2 PIR56278 ALDH5A1 DCDC2 | |
| GH06I024427 | Enhancer | 0.8 | Ensembl ENCODE | 47.6 | +25.7 | 25737 | 1.4 | PKNOX1 MAFG CEBPB EP300 ZNF217 ZFHX2 ATF4 MAFF ZNF316 IKZF1 | MRS2 RNU6-391P PIR53932 GPLD1 ALDH5A1 | |
| GH06I024431 | Enhancer | 0.7 | ENCODE | 33.5 | +28.3 | 28290 | 0.1 | ELF3 CTCF ZNF654 ARNT TRIM22 REST RAD21 CBX1 CBX5 KLF16 | MRS2 PIR53932 ALDH5A1 GPLD1 | |
| GH06I024359 | Enhancer | 1.2 | Ensembl ENCODE | 14.5 | -42.6 | -42634 | 1.4 | CLOCK ARNT SIN3A ZNF2 ZNF121 GLIS2 ZNF213 ZNF207 ZNF143 KLF7 | GC06P024361 MRS2 KAAG1 DCDC2 | |
| GH06I024385 | Enhancer | 1.1 | ENCODE dbSUPER | 5.9 | -17.1 | -17103 | 0.8 | FOXA2 MLX ARID4B DMAP1 ZNF48 ETS1 SLC30A9 ATF7 RXRA ZHX2 | MRS2 DCDC2 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around MRS2 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the MRS2 gene promoter:
Regulatory Element Products
Genomic Locations for MRS2 Gene
Genomic Locations for MRS2 Gene
- chr6:24,402,908-24,426,194
- (GRCh38/hg38)
- Size:
- 23,287 bases
- Orientation:
- Plus strand
- chr6:24,403,153-24,425,816
- (GRCh37/hg19)
Genomic View for MRS2 Gene
Genes around MRS2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p22.3 by Ensembl
- 6p22.3 by Entrez Gene
- 6p22.3 by HGNC
MRS2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MRS2 Gene
Proteins for MRS2 Gene
-
Protein details for MRS2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9HD23-MRS2_HUMAN
- Recommended name:
- Magnesium transporter MRS2 homolog, mitochondrial
- Protein Accession:
- Q9HD23
- A8K4U3
- B3KNN2
- B4DQL2
- Q5T3Y1
- Q6NTG4
- Q96KF8
- Q9BVP1
Protein attributes for MRS2 Gene
- Size:
- 443 amino acids
- Molecular mass:
- 50318 Da
- Quaternary structure:
- No Data Available
- Miscellaneous:
-
- Has the ability to complement a deletion of MRS2 in S.cerevisiae and partly restore mitochondrial magnesium concentrations.
- SequenceCaution:
-
- Sequence=CAI17109.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Protein Expression for MRS2 Gene
Post-translational modifications for MRS2 Gene
Other Protein References for MRS2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
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-
Abcam antibodies for MRS2
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- GeneTex MRS2 antibody for MRS2
Protein Products
-
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- Search GeneTex for Proteins for MRS2
-
Abcam proteins for MRS2
Assay Products
- antibodies-online: Search results for available MRS2 related products ranked by validation data
No data available for DME Specific Peptides for MRS2 Gene
Domains & Families for MRS2 Gene
Gene Families for MRS2 Gene
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
Protein Domains for MRS2 Gene
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for MRS2 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9HD23UniProtKB/Swiss-Prot:
MRS2_HUMAN :- Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
- Family:
-
- Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
Function for MRS2 Gene
Molecular function for MRS2 Gene
- UniProtKB/Swiss-Prot Function:
- Magnesium transporter that mediates the influx of magnesium into the mitochondrial matrix (PubMed:11401429, PubMed:18384665). Required for normal expression of the mitochondrial respiratory complex I subunits (PubMed:18384665).
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0015095 | magnesium ion transmembrane transporter activity | TAS | -- |
Phenotypes for MRS2 Gene
- GenomeRNAi human phenotypes for MRS2:
Animal Model Products
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-
-
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-
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-
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- genomics-online: gRNA clones - Search results for 110 available MRS2 gene related products
- Overview of 110 available MRS2 gene related products
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Vectors and viruses for KO, Activation, Repression, and more
-
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miRNA for MRS2 Gene
- miRTarBase miRNAs that target MRS2
-
- hsa-mir-155-5p (MIRT021034)
- hsa-mir-98-5p (MIRT027867)
- hsa-mir-744-5p (MIRT037639)
- hsa-mir-20a-5p (MIRT050531)
- hsa-let-7a-5p (MIRT052486)
- hsa-mir-607 (MIRT528049)
- hsa-mir-1263 (MIRT528050)
- hsa-mir-150-3p (MIRT528051)
- hsa-mir-6715b-3p (MIRT528052)
- hsa-mir-544a (MIRT640703)
- hsa-mir-5047 (MIRT640704)
- hsa-mir-1301-3p (MIRT640705)
- hsa-mir-642a-5p (MIRT640706)
- hsa-mir-4660 (MIRT640707)
- hsa-mir-26b-3p (MIRT640708)
- hsa-mir-17-3p (MIRT640709)
- hsa-mir-1205 (MIRT640710)
- hsa-mir-1184 (MIRT640711)
- hsa-mir-3158-5p (MIRT640712)
- hsa-mir-6892-3p (MIRT640713)
- hsa-mir-2276-5p (MIRT640714)
- hsa-mir-5197-5p (MIRT640715)
- hsa-mir-92b-3p (MIRT727148)
- hsa-mir-32-5p (MIRT727149)
- hsa-mir-92a-3p (MIRT727150)
miRNA Products
- Search ViGene Biosciences for MRS2
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-
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- Mammalian expression: PiggyBac
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- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
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-
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Horizon Cell Lines for MRS2
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ViGene Biosciences adenoviral particle packaged cDNA for MRS2 gene
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ViGene Biosciences lentiviral particle packaged cDNA for MRS2 gene
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No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MRS2 Gene
Localization for MRS2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for MRS2 Gene
- Mitochondrion inner membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| mitochondrion | 5 |
| plasma membrane | 2 |
| peroxisome | 1 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
| cytosol | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005739 | mitochondrion | IDA | 11401429 |
| GO:0005743 | mitochondrial inner membrane | TAS | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for MRS2 Gene
Pathways & Interactions for MRS2 Gene
Pathways by source for MRS2 Gene
2 Reactome pathways for MRS2 Gene
Interacting Proteins for MRS2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006089 | lactate metabolic process | IEA | -- |
| GO:0006810 | transport | IEA | -- |
| GO:0006811 | ion transport | IEA | -- |
| GO:0045016 | mitochondrial magnesium ion transmembrane transport | IMP | 11401429 |
| GO:0055085 | transmembrane transport | TAS | -- |
No data available for SIGNOR curated interactions for MRS2 Gene
Drugs & Compounds for MRS2 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Magnesium | Approved | Nutra | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Transcripts for MRS2 Gene
mRNA/cDNA for MRS2 Gene
- (5) REFSEQ mRNAs :
- (11) Additional mRNA sequences :
- (236) Selected AceView cDNA sequences:
- (6) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for MRS2 Gene
CRISPR Products
-
OriGene CRISPR knockouts for MRS2
- genomics-online: gRNA clones - Search results for 110 available MRS2 gene related products
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-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for MRS2
- GenScript: Design CRISPR guide RNA sequences for MRS2
miRNA Products
- Search ViGene Biosciences for MRS2
Inhibitory RNA Products
- Origene shrna, RNAi, and sirna products in human, mouse, rat for MRS2
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- genomics-online: shRNA clones - Search results for 110 available MRS2 gene related products
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-
ViGene Biosciences ready-to-package AAV shRNAs for MRS2 gene
Clone Products
- Sino Biological Human cDNA Clone for MRS2
- VectorBuilder custom plasmid, inducible vectors for MRS2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MRS2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MRS2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11a | · | 11b | · | 11c | ^ | 12a | · | 12b | · | 12c | · | 12d | · | 12e | ^ | 13 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - |
Expression for MRS2 Gene
This gene is overexpressed in Peripheral blood mononuclear cells (53.1) and Retina (13.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for MRS2 Gene
NURSA nuclear receptor signaling pathways regulating expression of MRS2 Gene:
MRS2SOURCE GeneReport for Unigene cluster for MRS2 Gene:
Hs.658612Evidence on tissue expression from TISSUES for MRS2 Gene
- Lung(4.4)
- Nervous system(3.7)
- Kidney(2)
Primer Products
-
OriGene qPCR primer pairs for MRS2
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for MRS2 Gene
Orthologs for MRS2 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | MRS2 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | MRS2 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | MRS2 33 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Mrs2 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Mrs2 33 16 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | MRS2 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | MRS2 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | MRS2 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | mrs2 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | LOC565251 33 |
|
||
| MRS2 34 |
|
OneToOne | |||
| Dr.22850 33 |
|
||||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.5335 33 |
|
||
| K. lactis yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0F02519g 33 |
|
||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | MRS2 33 34 |
|
||
| MFM1 34 36 |
|
OneToMany | |||
| A. gosspyii yeast (Ashbya gossypii) |
Saccharomycetes | AGOS_ADR359W 33 |
|
||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | MGT10 33 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os03g0684400 33 |
|
||
| fission yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | mrs2 33 |
|
||
| bread mold (Neurospora crassa) |
Ascomycetes | NCU09091 33 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.8669 34 |
|
OneToOne |
- Species where no ortholog for MRS2 was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for MRS2 Gene
Pseudogenes.org Pseudogenes for MRS2 Gene
No data available for Paralogs for MRS2 Gene
Variants for MRS2 Gene
| SNP ID | Clin | Chr 06 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000313054 | -- | 24,410,612(+) | G/C | intron_variant | |
| rs1000426842 | -- | 24,404,819(+) | G/A | intron_variant | |
| rs1000475260 | -- | 24,404,644(+) | G/T | intron_variant | |
| rs1000499126 | -- | 24,416,929(+) | T/C | intron_variant | |
| rs1000671974 | -- | 24,417,418(+) | TTTTGTTTT/TTTT | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2671548 | CNV | deletion | 23128226 |
| nsv1026638 | CNV | gain | 25217958 |
| nsv1125872 | CNV | tandem duplication | 24896259 |
Residual Variation Intolerance Score:
38.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.66;
78.42% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for MRS2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MRS2
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MRS2 Gene
Disorders for MRS2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| basilar artery occlusion |
|
|
Search MRS2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for MRS2
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for MRS2 Gene
Publications for MRS2 Gene
- The human mitochondrial Mrs2 protein functionally substitutes for its yeast homologue, a candidate magnesium transporter. (PMID: 11401429) Zsurka G … Schweyen RJ (Genomics 2001) 3 4 22 58
- Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson SL … O'Brien SJ (PloS one 2010) 3 44 58
- Conditional knockdown of hMRS2 results in loss of mitochondrial Mg(2+) uptake and cell death. (PMID: 18384665) Piskacek M … Schweyen RJ (Journal of cellular and molecular medicine 2009) 3 4 58
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
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- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for available MRS2 related products ranked by validation data
- antibodies-online: Search results for available MRS2 related products ranked by validation data
- antibodies-online: Search results for available MRS2 related products ranked by validation data
- GeneTex MRS2 antibody for MRS2
- Search GeneTex for Proteins for MRS2
- ViGene Biosciences adenoviral particle packaged cDNA for MRS2 gene
- ViGene Biosciences lentiviral particle packaged cDNA for MRS2 gene
- ViGene Biosciences ready-to-package AAV shRNAs for MRS2 gene
- Search ViGene Biosciences for MRS2
- Horizon Cell Lines for MRS2
- genomics-online: cdna clones - Search results for 110 available MRS2 gene related products
- Overview of 110 available MRS2 gene related products
- orf clones - Search results for 110 available MRS2 gene related products
- Overview of 110 available MRS2 gene related products
- genomics-online: gRNA clones - Search results for 110 available MRS2 gene related products
- Overview of 110 available MRS2 gene related products
- genomics-online: primer clones - Search results for 110 available MRS2 gene related products
- Overview of 110 available MRS2 gene related products
- genomics-online: shRNA clones - Search results for 110 available MRS2 gene related products
- Overview of 110 available MRS2 gene related products
Sources for MRS2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems