Aliases for MRPS28 Gene
External Ids for MRPS28 Gene
Previous GeneCards Identifiers for MRPS28 Gene
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that has been called mitochondrial ribosomal protein S35 in the literature. [provided by RefSeq, Jul 2008]
GeneCards Summary for MRPS28 Gene
MRPS28 (Mitochondrial Ribosomal Protein S28) is a Protein Coding gene. Diseases associated with MRPS28 include Combined Oxidative Phosphorylation Deficiency 47. Among its related pathways are Mitochondrial translation and Organelle biogenesis and maintenance.