Aliases for MRPS25 Gene
External Ids for MRPS25 Gene
Previous GeneCards Identifiers for MRPS25 Gene
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
GeneCards Summary for MRPS25 Gene
MRPS25 (Mitochondrial Ribosomal Protein S25) is a Protein Coding gene. Diseases associated with MRPS25 include Dyskinetic Cerebral Palsy and Multiple Endocrine Neoplasia, Type Iv. Among its related pathways are Organelle biogenesis and maintenance and Mitochondrial translation.