Aliases for MRPS23 Gene
External Ids for MRPS23 Gene
Previous GeneCards Identifiers for MRPS23 Gene
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 7p. [provided by RefSeq, Jul 2008]
GeneCards Summary for MRPS23 Gene
MRPS23 (Mitochondrial Ribosomal Protein S23) is a Protein Coding gene. Diseases associated with MRPS23 include Combined Oxidative Phosphorylation Deficiency 46 and Colorectal Cancer, Hereditary Nonpolyposis, Type 7. Among its related pathways are Mitochondrial translation and Organelle biogenesis and maintenance. Gene Ontology (GO) annotations related to this gene include structural constituent of ribosome.