Aliases for MRPL36 Gene
External Ids for MRPL36 Gene
Previous GeneCards Identifiers for MRPL36 Gene
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 2p. [provided by RefSeq, Jul 2008]
GeneCards Summary for MRPL36 Gene
MRPL36 (Mitochondrial Ribosomal Protein L36) is a Protein Coding gene. Diseases associated with MRPL36 include Mitochondrial Complex I Deficiency, Nuclear Type 1 and Wolf-Hirschhorn Syndrome. Among its related pathways are Mitochondrial translation and Viral mRNA Translation. Gene Ontology (GO) annotations related to this gene include structural constituent of ribosome.