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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian... See more...
Aliases for MRPL3 Gene
Aliases for MRPL3 Gene
External Ids for MRPL3 Gene
- HGNC: 10379
- NCBI Entrez Gene: 11222
- Ensembl: ENSG00000114686
- OMIM®: 607118
- UniProtKB/Swiss-Prot: P09001
Previous HGNC Symbols for MRPL3 Gene
- RPML3
Previous GeneCards Identifiers for MRPL3 Gene
- GC03M128092
- GC03M131922
- GC03M132462
- GC03M132501
- GC03M132663
- GC03M131181
- GC03M128565
Summaries for MRPL3 Gene
-
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L3P ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 13q. [provided by RefSeq, Jul 2008]
GeneCards Summary for MRPL3 Gene
MRPL3 (Mitochondrial Ribosomal Protein L3) is a Protein Coding gene. Diseases associated with MRPL3 include Combined Oxidative Phosphorylation Deficiency 9 and Penicilliosis. Among its related pathways are Mitochondrial translation and Viral mRNA Translation. Gene Ontology (GO) annotations related to this gene include structural constituent of ribosome.
Additional gene information for MRPL3 Gene
No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MRPL3 Gene
Genomics for MRPL3 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for MRPL3 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around MRPL3 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for MRPL3
- Top Transcription factor binding sites by QIAGEN in the MRPL3 gene promoter:
-
- AREB6
- NF-AT
- NF-AT1
- NF-AT2
- NF-AT3
- NF-AT4
- p300
- POU2F1
- POU2F1a
- S8
Genomic Locations for MRPL3 Gene
Latest Assembly
- chr3:131,462,212-131,502,983
- (GRCh38/hg38)
- Size:
- 40,772 bases
- Orientation:
- Minus strand
Previous Assembly
- chr3:131,181,056-131,221,815
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 40,760 bases
- Orientation:
- Minus strand
Genomic View for MRPL3 Gene
Genes around MRPL3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 3q22.1 by HGNC
- 3q22.1 by Entrez Gene
- 3q22.1 by Ensembl
MRPL3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MRPL3 Gene
Proteins for MRPL3 Gene
-
Protein details for MRPL3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P09001-RM03_HUMAN
- Recommended name:
- 39S ribosomal protein L3, mitochondrial
- Protein Accession:
- P09001
- Q6IBT2
Protein attributes for MRPL3 Gene
- Size:
- 348 amino acids
- Molecular mass:
- 38633 Da
- Quaternary structure:
-
- Component of the mitochondrial large ribosomal subunit (mt-LSU) (PubMed:28892042, PubMed:25838379, PubMed:25278503). Mature mammalian 55S mitochondrial ribosomes consist of a small (28S) and a large (39S) subunit. The 28S small subunit contains a 12S ribosomal RNA (12S mt-rRNA) and 30 different proteins. The 39S large subunit contains a 16S rRNA (16S mt-rRNA), a copy of mitochondrial valine transfer RNA (mt-tRNA(Val)), which plays an integral structural role, and 52 different proteins.
Protein Expression for MRPL3 Gene
Post-translational modifications for MRPL3 Gene
Other Protein References for MRPL3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- G Biosciences Immunotag™ MRPL3 Antibody
- Novus Biologicals Antibodies for MRPL3
-
Abcam antibodies for MRPL3
- Invitrogen Antibodies for MRPL3 (AFLGC-MRPL3)
-
Boster Bio Antibodies for MRPL3
-
Custom Antibody ServicesProSci Antibodies for MRPL3
-
Santa Cruz Biotechnology (SCBT) Antibodies for MRPL3
- Sino Biological Antibodies for MRPL3
Protein products for research
-
OriGene Purified Proteins for MRPL3
- Search Origene for MassSpec and Protein Over-expression Lysates for MRPL3
- Origene Custom Protein Services for MRPL3
- antibodies-online: Show 5 available MRPL3 Proteins ranked by validation data
- Compare Top MRPL3 Proteins
-
Quality Products:
-
Abcam proteins for MRPL3
Assay products for research
No data available for DME Specific Peptides for MRPL3 Gene
Domains & Families for MRPL3 Gene
Gene Families for MRPL3 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Disease related genes
- Predicted intracellular proteins
- Ribosomal proteins
Protein Domains for MRPL3 Gene
- InterPro:
- Blocks:
-
- Ribosomal protein L3
Suggested Antigen Peptide Sequences for MRPL3 Gene
- GenScript: Design optimal peptide antigens:
-
- Mitochondrial ribosomal protein L3 (Q96Q75_HUMAN)
- 39S ribosomal protein L3, mitochondrial (RM03_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P09001- Family:
-
- Belongs to the universal ribosomal protein uL3 family.
Function for MRPL3 Gene
Phenotypes From GWAS Catalog for MRPL3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003723 | RNA binding | TAS,HDA | 22658674 |
| GO:0003735 | structural constituent of ribosome | IEA,IBA | 21873635 |
Phenotypes for MRPL3 Gene
- MGI mutant phenotypes for MRPL3:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for MRPL3:
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for MRPL3 - Starting at $85 >
- * MRPL3 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for MRPL3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MRPL3
-
Santa Cruz Biotechnology (SCBT) CRISPR for MRPL3
miRNA for MRPL3 Gene
- miRTarBase miRNAs that target MRPL3
-
- hsa-miR-16-5p (MIRT031613)
- hsa-miR-484 (MIRT041694)
- hsa-miR-92a-3p (MIRT049158)
- hsa-miR-203b-3p (MIRT447597)
- hsa-miR-7158-3p (MIRT447598)
- hsa-miR-3202 (MIRT447599)
- hsa-miR-4680-5p (MIRT447600)
- hsa-miR-4533 (MIRT447601)
- hsa-miR-570-5p (MIRT447602)
- hsa-miR-548ba (MIRT447603)
- hsa-miR-548ai (MIRT447604)
- hsa-miR-548ag (MIRT447605)
- hsa-miR-100-3p (MIRT447606)
- hsa-miR-4252 (MIRT484451)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MRPL3
- Browse OriGene Inhibitory RNA Products For MRPL3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MRPL3
Clone products for research
- Applied Biological Materials (abm): Clones for MRPL3 - Starting at $45 >
- * MRPL3 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for MRPL3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MRPL3
No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for MRPL3 Gene
Localization for MRPL3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for MRPL3 Gene
- Mitochondrion.
| Compartment | Confidence |
|---|---|
| mitochondrion | 5 |
| nucleus | 2 |
| cytosol | 2 |
| cytoskeleton | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005739 | mitochondrion | IEA,IDA | 28892042 |
| GO:0005743 | mitochondrial inner membrane | TAS | -- |
| GO:0005762 | mitochondrial large ribosomal subunit | IBA,IDA | 20186120 |
| GO:0005840 | ribosome | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for MRPL3 Gene
Pathways & Interactions for MRPL3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Mitochondrial translation | ||
| 2 | Viral mRNA Translation |
.53
|
|
| 3 | Organelle biogenesis and maintenance | ||
Pathways by source for MRPL3 Gene
1 KEGG pathway for MRPL3 Gene
Interacting Proteins for MRPL3 Gene
GPS-Prot Interaction Network for MRPL3
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006412 | translation | IEA,TAS | 2891103 |
| GO:0070125 | mitochondrial translational elongation | TAS | -- |
| GO:0070126 | mitochondrial translational termination | TAS | -- |
No data available for SIGNOR curated interactions for MRPL3 Gene
Transcripts for MRPL3 Gene
mRNA/cDNA for MRPL3 Gene
- 1 REFSEQ mRNAs :
- 8 NCBI additional mRNA sequence :
- 10 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000264995 1708 nts (view in UCSC)
- ENST00000425847 1457 nts (view in UCSC)
- ENST00000506487 634 nts (view in UCSC)
- ENST00000506946 384 nts (view in UCSC)
- ENST00000507669 848 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for MRPL3 - Starting at $85 >
- * MRPL3 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for MRPL3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MRPL3
-
Santa Cruz Biotechnology (SCBT) CRISPR for MRPL3
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MRPL3
- Browse OriGene Inhibitory RNA Products For MRPL3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MRPL3
Clone products for research
- Applied Biological Materials (abm): Clones for MRPL3 - Starting at $45 >
- * MRPL3 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for MRPL3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MRPL3
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b |
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| SP3: | - | - | - | - | |||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | ||||||||||||||||||||||||||||||||||||
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| SP6: | |||||||||||||||||||||||||||||||||||||||
| SP7: |
Relevant External Links for MRPL3 Gene
- GeneLoc Exon Structure for
- MRPL3
Expression for MRPL3 Gene
This gene is overexpressed in Pancreas (28.5), Platelet (7.1), and Peripheral blood mononuclear cells (6.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for MRPL3 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MRPL3
SOURCE GeneReport for Unigene cluster for MRPL3 Gene:
Hs.205163Evidence on tissue expression from TISSUES for MRPL3 Gene
- Nervous system(4.4)
- Lung(2.3)
- Liver(2.1)
- Skin(2.1)
Phenotype-based relationships between genes and organs from Gene ORGANizer for MRPL3 Gene
Germ Layers:
- endoderm
- mesoderm
Systems:
- cardiovascular
- digestive
- respiratory
Regions:
Head and neck:
- ear
Thorax:
- heart
- heart valve
Abdomen:
- liver
Primer products for research
-
OriGene qPCR primer pairs for MRPL3
-
OriGene qPCR primer pairs and template standards for MRPL3
Gene Expression Assays for research
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for MRPL3 Gene
Orthologs for MRPL3 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | MRPL3 29 30 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | MRPL3 29 30 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | MRPL3 29 30 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Mrpl3 29 16 30 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Mrpl3 29 |
|
||
| Platypus (Ornithorhynchus anatinus) |
Mammalia | MRPL3 30 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | MRPL3 30 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | MRPL3 29 30 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | MRPL3 30 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | mrpl3 29 |
|
||
| Str.20499 29 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.8380 29 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | mrpl3 29 30 |
|
OneToOne | |
| -- 29 |
|
||||
| Fruit Fly (Drosophila melanogaster) |
Insecta | mRpL3 29 30 31 |
|
OneToOne | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP000857 29 |
|
||
| Worm (Caenorhabditis elegans) |
Secernentea | mrps-18C 29 30 |
|
OneToOne | |
| C26E6.6 31 |
|
|
|||
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | MRPL9 29 30 32 |
|
OneToOne | |
| A. gosspyii yeast (Eremothecium gossypii) |
Saccharomycetes | AGOS_ADL129W 29 |
|
||
| K. Lactis Yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0E16039g 29 |
|
||
| Thale Cress (Arabidopsis thaliana) |
eudicotyledons | RPL3P 29 |
|
||
| Rice (Oryza sativa) |
Liliopsida | Os01g0251100 29 |
|
||
| Fission Yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | mrpl9 29 |
|
||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 30 |
|
OneToOne | |
| Bread mold (Neurospora crassa) |
Ascomycetes | NCU06749 29 |
|
- Species where no ortholog for MRPL3 was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for MRPL3 Gene
- ENSEMBL:
- Gene Tree for MRPL3 (if available)
- TreeFam:
- Gene Tree for MRPL3 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for MRPL3: view image
- Alliance of Genome Resources:
- Additional Orthologs for MRPL3
Paralogs for MRPL3 Gene
Pseudogenes.org Pseudogenes for MRPL3 Gene
No data available for Paralogs for MRPL3 Gene
Variants for MRPL3 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MRPL3 Gene
| SNP ID | Clinical significance and condition | Chr 03 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 1027733 | Uncertain Significance: Combined oxidative phosphorylation deficiency 9 | 131,468,123(-) |
A/G NM_007208.4(MRPL3):c.862T>C (p.Ser288Pro) |
MISSENSE | |
| 1032531 | Pathogenic: Combined oxidative phosphorylation deficiency 9 | 131,501,665(-) |
C/T NM_007208.4(MRPL3):c.143G>A (p.Trp48Ter) |
NONSENSE | |
| 1033195 | Pathogenic: Combined oxidative phosphorylation deficiency 9 | 131,501,541(-) |
AG/A NM_007208.4(MRPL3):c.266del (p.Pro89fs) |
FRAMESHIFT | |
| rs1057523049 | Likely Benign: not specified | 131,469,780(-) |
G/A NM_007208.4(MRPL3):c.739-7C>T |
INTRON | |
| rs1064793180 | Uncertain Significance: not provided | 131,487,738(-) |
T/G NM_007208.4(MRPL3):c.571A>C (p.Thr191Pro) |
MISSENSE |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3597781 | CNV | gain | 21293372 |
| nsv1006656 | CNV | gain | 25217958 |
| nsv829724 | CNV | gain | 17160897 |
Residual Variation Intolerance Score:
60.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.50;
43.81% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for MRPL3 Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MRPL3 Gene
Disorders for MRPL3 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| combined oxidative phosphorylation deficiency 9 |
|
|
| penicilliosis |
|
|
| hypertrophic cardiomyopathy |
|
|
Search MRPL3 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
RM03_HUMAN- Combined oxidative phosphorylation deficiency 9 (COXPD9) [MIM:614582]: A mitochondrial disease characterized by failure to thrive, poor feeding, hypertrophic cardiomyopathy, hepatomegaly, and psychomotor retardation. Death in infancy has been observed in some cases. {ECO:0000269 PubMed:21786366}. Note=The disease is caused by variants affecting the gene represented in this entry.
Additional Disease Information for MRPL3
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for Genatlas for MRPL3 Gene
Publications for MRPL3 Gene
- Exome sequencing identifies MRPL3 mutation in mitochondrial cardiomyopathy. (PMID: 21786366) Galmiche L … Rötig A (Human mutation 2011) 3 4 72
- Cloning and characterization of a human ribosomal protein gene with enhanced expression in fetal and neoplastic cells. (PMID: 2891103) Ou JH … Rutter WJ (Nucleic acids research 1987) 2 3 4
- Structures of the human mitochondrial ribosome in native states of assembly. (PMID: 28892042) Brown A … Ramakrishnan V (Nature structural & molecular biology 2017) 3 4
- Structure of the large ribosomal subunit from human mitochondria. (PMID: 25278503) Brown A … Ramakrishnan V (Science (New York, N.Y.) 2014) 3 4
- Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson SL … O'Brien SJ (PloS one 2010) 3 40
ExternalLinks
Products for MRPL3 Gene
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for MRPL3
- Search Origene for MassSpec and Protein Over-expression Lysates for MRPL3
- Origene Custom Protein Services for MRPL3
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MRPL3
- Browse OriGene Inhibitory RNA Products For MRPL3
- OriGene qPCR primer pairs for MRPL3
- OriGene qPCR primer pairs and template standards for MRPL3
- OriGene CRISPR knockouts for MRPL3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For MRPL3
- Sino Biological Human cDNA Clone for MRPL3
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for MRPL3
- Browse Sino Biological Assays
- Browse Antibodies
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for MRPL3
- Novus Biologicals proteins and lysates for MRPL3
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for MRPL3
- Abcam proteins for MRPL3
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for MRPL3 (AFLGC-MRPL3)
- VectorBuilder Custom and pre-made DNA vectors for MRPL3 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for MRPL3 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for MRPL3 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for MRPL3 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for MRPL3
- antibodies-online: Show 15 available MRPL3 Antibodies ranked by validation data
- Compare Top MRPL3 Antibodies
- antibodies-online: Search results for available MRPL3 related products ranked by validation data
- antibodies-online: Show 5 available MRPL3 Proteins ranked by validation data
- Compare Top MRPL3 Proteins
- Quality Products:
- Santa Cruz Biotechnology (SCBT) Antibodies for MRPL3
- Search Santa Cruz Biotechnology (SCBT) for MRPL3 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for MRPL3
- Custom Antibody ServicesProSci Antibodies for MRPL3
- Search for MRPL3 Proteins at ProSci
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MRPL3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MRPL3
- Search GeneCopoeia for miRNA 3'UTR Target clone products for MRPL3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MRPL3
- Boster Bio Antibodies for MRPL3
- Browse Boster Bio ELISA Kits
Sources for MRPL3 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Apr-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) ASD
- (27) SAGE
- (28) SOURCE
- (29) HomoloGene
- (30) PanEnsembl
- (31) euGenes
- (32) SGD
- (33) FlyBase
- (34) WormBase
- (35) Pseudogene
- (36) DGV
- (37) dbSNP
- (38) GenAtlas
- (39) HGMD
- (40) GAD
- (41) BGMUT
- (42) HuGE
- (43) Atlas
- (44) GenBank
- (45) HORDE
- (46) HUGE
- (47) IMGT
- (48) Leiden
- (49) miRBase
- (50) DME
- (51) OriGene
- (52) PubMed
- (53) R&D Systems
- (54) Tocris
- (55) Abcam
- (56) Novus Biologicals
- (57) ProSpec
- (58) Sino Biological
- (59) GenScript
- (60) Qiagen
- (61) OCA
- (62) Proteopedia
- (63) MOPED
- (64) neXtProt
- (65) Reactome
- (66) GeneGo (Thomson Reuters)
- (67) DISEASES
- (68) SIMAP
- (69) GenomeRNAi
- (70) LifeMap
- (71) miRTarBase
- (72) MalaCards
- (73) Invitrogen
- (74) BitterDB
- (75) ESI-BIO
- (76) RefSeq
- (77) BioSystems
- (78) MaxQB
- (79) IUPHAR
- (80) BioGPS
- (81) Illumina
- (82) COMPARTMENTS
- (83) HOMER
- (84) PaxDb
- (85) ApexBio
- (86) Addgene
- (87) antibodies-online
- (88) CYP
- (89) NONCODE
- (90) TreeFam
- (91) PathCards
- (92) GeneReviews
- (93) GeneTex
- (94) Taconic Biosciences
- (95) GTEx
- (96) ProteomicsDB
- (97) SCBT
- (98) DGIdb
- (99) ClinicalTrials
- (100) RVIS
- (101) SIGNOR
- (102) diseasecard
- (103) NIH Rare Diseases
- (104) Orphanet
- (105) UMLS
- (106) GTR
- (107) Disease Ontology
- (108) MedlinePlus Genetics
- (109) MeSH
- (110) MedlinePlus
- (111) CDC
- (112) NINDS
- (113) NCBI Bookshelf
- (114) ClinVar
- (115) Gene Damage Index
- (116) HPO
- (117) UDN
- (118) VISTA
- (119) FANTOM5
- (120) ENCODE
- (121) ProSci
- (122) Horizon
- (123) The Signaling Pathways Project (SPP)
- (124) IID
- (125) VectorBuilder
- (126) SNPedia
- (127) BRCA Exchange
- (128) CIViC
- (129) ProteoGenix
- (130) dbSUPER
- (131) TISSUES
- (132) Gene ORGANizer
- (133) abm
- (134) Human Protein Atlas
- (135) GWAS Catalog
- (136) Monarch Initiative
- (137) DataMed
- (138) HumanCyc
- (139) UCNEbase
- (140) EPDnew
- (141) Applied Biosystems
- (142) GlyConnect
- (143) Aminode
- (144) GeneCopoeia
- (145) GPS-Prot
- (146) RNAcentral
- (147) LncRNADisease
- (148) LOVD
- (149) miR2Disease
- (150) DiseaseEnhancer
- (151) Boster Bio
- (152) Biorbyt
- (153) Biocompare
- (154) Mastermind
- (155) CTD^2 Dashboard
- (156) CraniofacialAtlas
- (157) GeneImprint
- (158) Synthego
- (159) ENA
- (160) GtRNAdb
- (161) LncBase
- (162) LncBook
- (163) LNCipedia
- (164) Modomics
- (165) PDBe
- (166) Rfam
- (167) SILVA
- (168) snOPY
- (169) SRPDB
- (170) GENCODE
- (171) TarBase
- (172) Open Targets Platform
- (173) 5SRRNADB
- (174) snoDB
- (175) MirGeneDB
- (176) Alliance of Genome Resources