Aliases for MRGPRD Gene
External Ids for MRGPRD Gene
Previous GeneCards Identifiers for MRGPRD Gene
GeneCards Summary for MRGPRD Gene
MRGPRD (MAS Related GPR Family Member D) is a Protein Coding gene. Diseases associated with MRGPRD include Femoral Cancer and Liver Rhabdomyosarcoma. Among its related pathways are Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity. An important paralog of this gene is MRGPRX2.
UniProtKB/Swiss-Prot Summary for MRGPRD Gene
May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).