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This gene encodes an intracellular protein that interacts with members of the MORF4/MRG (mortality factor on chromosome 4/MORF4 related gene) family and the tumor suppressor Rb (retinoblastoma protein.) The protein may play a role in senescence, cell growth and immortalization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013] See more...
Aliases for MRFAP1 Gene
Aliases for MRFAP1 Gene
External Ids for MRFAP1 Gene
- HGNC: 24549
- Entrez Gene: 93621
- Ensembl: ENSG00000179010
- OMIM: 616905
- UniProtKB: Q9Y605
Previous GeneCards Identifiers for MRFAP1 Gene
- GC04P006761
- GC04P006692
- GC04P006643
- GC04P006573
Summaries for MRFAP1 Gene
-
This gene encodes an intracellular protein that interacts with members of the MORF4/MRG (mortality factor on chromosome 4/MORF4 related gene) family and the tumor suppressor Rb (retinoblastoma protein.) The protein may play a role in senescence, cell growth and immortalization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
GeneCards Summary for MRFAP1 Gene
MRFAP1 (Morf4 Family Associated Protein 1) is a Protein Coding gene. An important paralog of this gene is MRFAP1L1.
Additional gene information for MRFAP1 Gene
- HGNC(24549)
- Entrez Gene(93621)
- Ensembl(ENSG00000179010)
- OMIM(616905)
- UniProtKB(Q9Y605)
- Open Targets Platform(ENSG00000179010)
- Search for MRFAP1 at DataMed
- Search for MRFAP1 at HumanCyc
No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MRFAP1 Gene
Genomics for MRFAP1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for MRFAP1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around MRFAP1 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for MRFAP1
- Top Transcription factor binding sites by QIAGEN in the MRFAP1 gene promoter:
-
- CBF(2)
- CBF-A
- HFH-1
- POU2F1
- POU2F1a
- POU3F2
- POU3F2 (N-Oct-5a)
- POU3F2 (N-Oct-5b)
- SRF
- SRF (504 AA)
Genomic Locations for MRFAP1 Gene
Genomic Locations for MRFAP1 Gene
- chr4:6,640,091-6,642,745
- (GRCh38/hg38)
- Size:
- 2,655 bases
- Orientation:
- Plus strand
- chr4:6,641,818-6,644,472
- (GRCh37/hg19)
- Size:
- 2,655 bases
- Orientation:
- Plus strand
Genomic View for MRFAP1 Gene
Genes around MRFAP1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 4p16.1 by HGNC
- 4p16.1 by Entrez Gene
- 4p16.1 by Ensembl
MRFAP1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MRFAP1 Gene
Proteins for MRFAP1 Gene
-
Protein details for MRFAP1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9Y605-MOFA1_HUMAN
- Recommended name:
- MORF4 family-associated protein 1
- Protein Accession:
- Q9Y605
- B3KVT2
- D3DVT3
Protein attributes for MRFAP1 Gene
- Size:
- 127 amino acids
- Molecular mass:
- 14650 Da
- Quaternary structure:
-
- Found in a complex composed of MORF4L1, MRFAP1 and RB1. Interacts via its N-terminus with MORF4L1. Interacts with CSTB and MORF4L2.
Protein Expression for MRFAP1 Gene
Post-translational modifications for MRFAP1 Gene
Other Protein References for MRFAP1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- G Biosciences Immunotag™ MRFAP1 Antibody
-
Custom Antibody ServicesOriGene Antibodies for MRFAP1
- Novus Biologicals Antibodies for MRFAP1
- Invitrogen Antibodies for MRFAP1 (AFLGC-MRFAP1)
-
Boster Bio Antibodies for MRFAP1
Protein Products
-
OriGene Purified Proteins for MRFAP1
- Search Origene for MassSpec and Protein Over-expression Lysates for MRFAP1
- Origene Custom Protein Services for MRFAP1
- antibodies-online: Show 5 available MRFAP1 Proteins ranked by validation data
- Compare Top MRFAP1 Proteins
-
Quality Products:
Assay Products
- antibodies-online: Show 7 available MRFAP1 Elisa Kits ranked by validation data
- Compare Top MRFAP1 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for MRFAP1 Gene
Domains & Families for MRFAP1 Gene
Gene Families for MRFAP1 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Suggested Antigen Peptide Sequences for MRFAP1 Gene
- GenScript: Design optimal peptide antigens:
-
- Protein associated with MRG of 14 kDa (MOFA1_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9Y605- Family:
-
- Belongs to the MORF4 family-associated protein family.
Function for MRFAP1 Gene
Phenotypes From GWAS Catalog for MRFAP1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 11500496 |
Phenotypes for MRFAP1 Gene
- MGI mutant phenotypes for MRFAP1:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for MRFAP1:
-
- Increased vaccinia virus (VACV) infection
- Mildly decreased CFP-tsO45G cell surface transport
- no effect
- Synthetic lethal with MLN4924 (a NAE inhibitor)
- Increased viability with MLN4924 (a NAE inhibitor)
- Resistant to vaccinia virus (VACV-A4L) infection
- Decreased viability ratio
- Increased ionizing radiation sensitivity
- Decreased viability after ionizing radiation
Animal Models for MRFAP1 Gene
- MGI Knock Outs for MRFAP1:
-
- Mrfap1 Mrfap1<tm1Kto>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for MRFAP1 - Select products 50% OFF >
- * MRFAP1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for MRFAP1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MRFAP1
-
Santa Cruz Biotechnology (SCBT) CRISPR for MRFAP1
miRNA for MRFAP1 Gene
- miRTarBase miRNAs that target MRFAP1
-
- mmu-miR-26a-5p (MIRT011116)
- hsa-miR-1-3p (MIRT023865)
- hsa-miR-16-5p (MIRT031820)
- hsa-miR-615-3p (MIRT039701)
- hsa-miR-423-3p (MIRT042574)
- hsa-miR-328-3p (MIRT043774)
- hsa-miR-186-5p (MIRT045034)
- hsa-miR-142-3p (MIRT440218)
- hsa-miR-552-5p (MIRT556070)
- hsa-miR-302c-5p (MIRT556071)
- hsa-miR-4477a (MIRT556072)
- hsa-miR-3143 (MIRT556073)
- hsa-miR-8068 (MIRT556074)
- hsa-miR-5003-3p (MIRT556075)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MRFAP1
- Browse OriGene Inhibitory RNA Products For MRFAP1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MRFAP1
Clone Products
- Applied Biological Materials (abm): Clones for MRFAP1 - Select products 50% OFF >
- * MRFAP1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for MRFAP1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MRFAP1
Cell Line Products
-
Horizon Cell Lines for MRFAP1
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for MRFAP1 Gene
Localization for MRFAP1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for MRFAP1 Gene
- Nucleus. Cytoplasm, perinuclear region. Note=Colocalizes with MORF4L1 to cell nuclei. {ECO:0000269 PubMed:11500496, ECO:0000269 PubMed:12397079}.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 2 |
| cytoskeleton | 1 |
| extracellular | 0 |
- Nucleoplasm (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0048471 | perinuclear region of cytoplasm | IEA | -- |
Pathways & Interactions for MRFAP1 Gene
Interacting Proteins for MRFAP1 Gene
Selected Interacting proteins:
Q9Y605-MOFA1_HUMAN
ENSP00000318352
for MRFAP1 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for MRFAP1
No data available for Pathways by source and SIGNOR curated interactions for MRFAP1 Gene
Transcripts for MRFAP1 Gene
mRNA/cDNA for MRFAP1 Gene
- 3 REFSEQ mRNAs :
- 17 NCBI additional mRNA sequence :
- 5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000320912 2049 nts (view in UCSC)
- ENST00000382581 1584 nts (view in UCSC)
- ENST00000507420 563 nts (view in UCSC)
- ENST00000512914 1982 nts (view in UCSC)
- ENST00000617365 2112 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for MRFAP1 - Select products 50% OFF >
- * MRFAP1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for MRFAP1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MRFAP1
-
Santa Cruz Biotechnology (SCBT) CRISPR for MRFAP1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MRFAP1
- Browse OriGene Inhibitory RNA Products For MRFAP1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MRFAP1
Clone Products
- Applied Biological Materials (abm): Clones for MRFAP1 - Select products 50% OFF >
- * MRFAP1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for MRFAP1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MRFAP1
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c | · | 5d | · | 5e |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||||
| SP2: | |||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||
| SP4: | - | - | |||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||
| SP6: |
Relevant External Links for MRFAP1 Gene
- GeneLoc Exon Structure for
- MRFAP1
Expression for MRFAP1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
- Intermediate Mesoderm (Gastrulation Derivatives)
- Intestine (Gastrointestinal Tract)
- Bone (Muscoskeletal System)
-
Uterus (Reproductive System)
-
Colon (Gastrointestinal Tract)
-
Prostate (Endocrine System)
-
Placenta (Extraembryonic Tissues)
-
Spleen (Hematopoietic System)
-
Thyroid (Endocrine System)
-
Gall Bladder (Hepatobiliary System)
-
Lung (Respiratory System)
-
Kidney (Urinary System)
-
Testis (Reproductive System)
-
Adrenal Gland (Endocrine System)
-
Esophagus (Gastrointestinal Tract)
-
Stomach (Gastrointestinal Tract)
-
Liver (Hepatobiliary System)
-
Pancreas (Endocrine System)
-
Ovary (Reproductive System)
-
Adipose (Muscoskeletal System)
This gene is overexpressed in Fetal ovary (13.8), Bone (12.2), Ovary (9.8), and Prostate (8.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for MRFAP1 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MRFAP1
SOURCE GeneReport for Unigene cluster for MRFAP1 Gene:
Hs.406590Evidence on tissue expression from TISSUES for MRFAP1 Gene
- Nervous system(5)
- Lung(3.5)
- Liver(3.1)
- Intestine(2.9)
- Heart(2.8)
- Spleen(2.8)
- Kidney(2.7)
- Muscle(2.7)
- Skin(2.6)
- Eye(2.6)
- Stomach(2.5)
- Adrenal gland(2.2)
- Thyroid gland(2)
Primer Products
-
OriGene qPCR primer pairs for MRFAP1
-
OriGene qPCR primer pairs and template standards for MRFAP1
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for MRFAP1 Gene
Orthologs for MRFAP1 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Cow (Bos Taurus) |
Mammalia | MRFAP1 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | MRFAP1 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Mrfap1 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Mrfap1 30 17 31 |
|
OneToMany | |
| Gm5814 31 |
|
OneToMany |
- Species where no ortholog for MRFAP1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chimpanzee (Pan troglodytes)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Evolution for MRFAP1 Gene
- ENSEMBL:
- Gene Tree for MRFAP1 (if available)
- TreeFam:
- Gene Tree for MRFAP1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for MRFAP1: view image
Paralogs for MRFAP1 Gene
Paralogs for MRFAP1 Gene
(1) SIMAP similar genes for MRFAP1 Gene using alignment to 1 proteins:
- MOFA1_HUMAN
Pseudogenes.org Pseudogenes for MRFAP1 Gene
Variants for MRFAP1 Gene
Residual Variation Intolerance Score:
36.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.14;
3.15% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for MRFAP1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MRFAP1
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MRFAP1 Gene
Disorders for MRFAP1 Gene
Additional Disease Information for MRFAP1
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No disorders were found for MRFAP1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MRFAP1 Gene
Publications for MRFAP1 Gene
- The MRG domain of human MRG15 uses a shallow hydrophobic pocket to interact with the N-terminal region of PAM14. (PMID: 17008723) Zhang P … Ding J (Protein science : a publication of the Protein Society 2006) 3 4
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- PAM14, a novel MRG- and Rb-associated protein, is not required for development and T-cell function in mice. (PMID: 15367658) Tominaga K … Pereira-Smith OM (Molecular and cellular biology 2004) 2 3
- MRGX is a novel transcriptional regulator that exhibits activation or repression of the B-myb promoter in a cell type-dependent manner. (PMID: 14506250) Tominaga K … Pereira-Smith OM (The Journal of biological chemistry 2003) 3 4
- MRG15, a novel chromodomain protein, is present in two distinct multiprotein complexes involved in transcriptional activation. (PMID: 12397079) Pardo PS … Pereira-Smith OM (The Journal of biological chemistry 2002) 3 4
ExternalLinks
Products for MRFAP1 Gene
- Custom Antibody ServicesOriGene Antibodies for MRFAP1
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for MRFAP1
- Search Origene for MassSpec and Protein Over-expression Lysates for MRFAP1
- Origene Custom Protein Services for MRFAP1
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MRFAP1
- Browse OriGene Inhibitory RNA Products For MRFAP1
- OriGene qPCR primer pairs for MRFAP1
- OriGene qPCR primer pairs and template standards for MRFAP1
- OriGene CRISPR knockouts for MRFAP1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For MRFAP1
- Sino Biological Human cDNA Clone for MRFAP1
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for MRFAP1
- Novus Biologicals proteins and lysates for MRFAP1
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for MRFAP1 (AFLGC-MRFAP1)
- VectorBuilder Custom and pre-made DNA vectors for MRFAP1 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for MRFAP1 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for MRFAP1 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for MRFAP1 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for MRFAP1
- antibodies-online: Show 4 available MRFAP1 Antibodies ranked by validation data
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- antibodies-online: Show 7 available MRFAP1 Elisa Kits ranked by validation data
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- Quality Products:
- antibodies-online: Show 5 available MRFAP1 Proteins ranked by validation data
- Compare Top MRFAP1 Proteins
- Quality Products:
- Horizon Cell Lines for MRFAP1
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MRFAP1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MRFAP1
- Search GeneCopoeia for miRNA 3'UTR Target clone products for MRFAP1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MRFAP1
- Boster Bio Antibodies for MRFAP1
- Browse Boster Bio ELISA Kits
Sources for MRFAP1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB