Aliases for MPV17 Gene
Aliases for MPV17 Gene
External Ids for MPV17 Gene
- HGNC: 7224
- Entrez Gene: 4358
- Ensembl: ENSG00000115204
- OMIM: 137960
- UniProtKB: P39210
Previous GeneCards Identifiers for MPV17 Gene
- GC02M027453
- GC02M027624
- GC02M027506
- GC02M027444
- GC02M027385
- GC02M027532
Summaries for MPV17 Gene
-
This gene encodes a mitochondrial inner membrane protein that is implicated in the metabolism of reactive oxygen species. Mutations in this gene have been associated with the hepatocerebral form of mitochondrial DNA depletion syndrome (MDDS). [provided by RefSeq, Jul 2008]
GeneCards Summary for MPV17 Gene
MPV17 (MPV17, Mitochondrial Inner Membrane Protein) is a Protein Coding gene. Diseases associated with MPV17 include Mitochondrial Dna Depletion Syndrome 6 and Nephrotic Syndrome. Among its related pathways are Peroxisome. An important paralog of this gene is MPV17L2.
UniProtKB/Swiss-Prot for MPV17 Gene
-
Involved in mitochondria homeostasis. May be involved in the metabolism of reactive oxygen species and control of oxidative phosphorylation and mitochondrial DNA (mtDNA) maintenance.
Additional gene information for MPV17 Gene
- Monarch Initiative
- Search for MPV17 at DataMed
- Search for MPV17 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MPV17 Gene
Genomics for MPV17 Gene
GeneHancer (GH) Regulatory Elements for MPV17 Gene
Promoters and enhancers for MPV17 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around MPV17 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the MPV17 gene promoter:
-
- Sp1
- C/EBPalpha
- GATA-1
- GATA-2
- GATA-3
- Roaz
- c-Rel
- p53
- Max
Regulatory Element Products
Genomic Locations for MPV17 Gene
Genomic Locations for MPV17 Gene
- chr2:27,309,490-27,325,680
- (GRCh38/hg38)
- Size:
- 16,191 bases
- Orientation:
- Minus strand
- chr2:27,532,360-27,548,547
- (GRCh37/hg19)
- Size:
- 16,188 bases
- Orientation:
- Minus strand
Genomic View for MPV17 Gene
Genes around MPV17 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2p23.3 by Entrez Gene
- 2p23.3 by HGNC
- 2p23.3 by Ensembl
MPV17 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MPV17 Gene
Proteins for MPV17 Gene
-
Protein details for MPV17 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P39210-MPV17_HUMAN
- Recommended name:
- Protein Mpv17
- Protein Accession:
- P39210
- D6W555
- Q53SY2
- Q96B08
Protein attributes for MPV17 Gene
- Size:
- 176 amino acids
- Molecular mass:
- 19733 Da
- Quaternary structure:
- No Data Available
Protein Expression for MPV17 Gene
Post-translational modifications for MPV17 Gene
Other Protein References for MPV17 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for MPV17
- Novus Biologicals Antibodies for MPV17
-
Abcam antibodies for MPV17
- Invitrogen Antibodies for MPV17 (AFLGC-MPV17)
- GeneTex MPV17 Antibody for MPV17
Protein Products
-
OriGene Purified Proteins for MPV17
- Search Origene for MassSpec and Protein Over-expression Lysates for MPV17
- Origene Custom Protein Services for MPV17
- Search GeneTex for Proteins for MPV17
-
Abcam proteins for MPV17
Assay Products
No data available for DME Specific Peptides for MPV17 Gene
Domains & Families for MPV17 Gene
Gene Families for MPV17 Gene
- Human Protein Atlas (HPA):
-
- Disease related genes
- Potential drug targets
- Predicted intracellular proteins
- Predicted membrane proteins
- Transporters
Protein Domains for MPV17 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for MPV17 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P39210- Family:
-
- Belongs to the peroxisomal membrane protein PXMP2/4 family.
Function for MPV17 Gene
Molecular function for MPV17 Gene
- UniProtKB/Swiss-Prot Function:
- Involved in mitochondria homeostasis. May be involved in the metabolism of reactive oxygen species and control of oxidative phosphorylation and mitochondrial DNA (mtDNA) maintenance.
- GENATLAS Biochemistry:
- mouse glomerulosclerosis gene Mpv17,homolog,peroxisomal,located in the 5utr region of the UCN gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003674 | molecular_function | ND | -- |
| GO:0005515 | protein binding | IPI | -- |
Phenotypes for MPV17 Gene
- MGI mutant phenotypes for MPV17:
-
inferred from 1 alleles
- cardiovascular system phenotype
- pigmentation phenotype
- homeostasis/metabolism phenotype
- nervous system phenotype
- behavior/neurological phenotype
- integument phenotype
- endocrine/exocrine gland phenotype
- mortality/aging
- cellular phenotype
- muscle phenotype
- liver/biliary system phenotype
- skeleton phenotype
- hearing/vestibular/ear phenotype
- renal/urinary system phenotype
- adipose tissue phenotype
- hematopoietic system phenotype
- growth/size/body region phenotype
- GenomeRNAi human phenotypes for MPV17:
-
- Dynamic nuclei (hole, folded or small irregular)
- Decreased viability with TRAIL
- Decreased viability
- no effect
- Increased vaccinia virus (VACV) infection
- Increased shRNA abundance
- Increased gamma-H2AX phosphorylation
- Decreased viability with paclitaxel
- Mildly decreased CFP-tsO45G cell surface transport
- Strongly decreased CFP-tsO45G cell surface transport
- Increased viability
- Increased transferrin (TF) endocytosis
- FOXO1 nuclear localization
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MPV17
-
CRISPR Products
-
OriGene CRISPR knockouts for MPV17
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MPV17
- genomics-online: gRNA clones - Search results for 90 available MPV17 gene related products
- Overview of 90 available MPV17 gene related products
- Applied Biological Materials CRISPR for MPV17
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for MPV17
- GenScript: Design CRISPR guide RNA sequences for MPV17
miRNA for MPV17 Gene
- miRTarBase miRNAs that target MPV17
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MPV17
- Browse OriGene Inhibitory RNA Products For MPV17
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MPV17
- genomics-online: shRNA clones - Search results for 90 available MPV17 gene related products
- Overview of 90 available MPV17 gene related products
Clone Products
- Sino Biological Human cDNA Clone for MPV17
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MPV17
- Applied Biological Materials Clones for MPV17
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Animal Models , Transcription Factor Targets and HOMER Transcription for MPV17 Gene
Localization for MPV17 Gene
Subcellular locations from UniProtKB/Swiss-Prot for MPV17 Gene
- Mitochondrion inner membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| mitochondrion | 5 |
| peroxisome | 5 |
| cytosol | 2 |
| plasma membrane | 1 |
| extracellular | 1 |
| nucleus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IBA | -- |
| GO:0005739 | mitochondrion | IDA | 16582910 |
| GO:0005743 | mitochondrial inner membrane | IDA,IEA | 16582910 |
| GO:0005777 | peroxisome | NAS | 7957077 |
| GO:0016020 | membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for MPV17 Gene
Pathways & Interactions for MPV17 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Peroxisome | ||
Pathways by source for MPV17 Gene
1 KEGG pathway for MPV17 Gene
Interacting Proteins for MPV17 Gene
GPS-Prot Interaction Network for MPV17
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000002 | mitochondrial genome maintenance | IMP | 16582910 |
| GO:0032836 | glomerular basement membrane development | ISS | -- |
| GO:0034614 | cellular response to reactive oxygen species | ISS | -- |
| GO:0042592 | homeostatic process | IMP | 16582910 |
| GO:0048839 | inner ear development | ISS | -- |
No data available for SIGNOR curated interactions for MPV17 Gene
Transcripts for MPV17 Gene
mRNA/cDNA for MPV17 Gene
- (7) REFSEQ mRNAs :
- (6) Additional mRNA sequences :
- (379) Selected AceView cDNA sequences:
- (23) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000620797 624 bps (uc061hmq.1)
- ENST00000233545 998 bps (uc002rjr.3)
- ENST00000402310 906 bps (uc061hmr.1)
- ENST00000380044 1005 bps (uc002rjs.4)
- ENST00000357186 2011 bps (uc061hms.1)
Unigene Clusters for MPV17 Gene
- MpV17 mitochondrial inner membrane protein:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for MPV17
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MPV17
- genomics-online: gRNA clones - Search results for 90 available MPV17 gene related products
- Overview of 90 available MPV17 gene related products
- Applied Biological Materials CRISPR for MPV17
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for MPV17
- GenScript: Design CRISPR guide RNA sequences for MPV17
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MPV17
- Browse OriGene Inhibitory RNA Products For MPV17
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MPV17
- genomics-online: shRNA clones - Search results for 90 available MPV17 gene related products
- Overview of 90 available MPV17 gene related products
Clone Products
- Sino Biological Human cDNA Clone for MPV17
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MPV17
- Applied Biological Materials Clones for MPV17
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | · | 12c | · | 12d | · | 12e | · | 12f |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP10: | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP11: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP12: | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP13: | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP14: | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP15: | - |
Expression for MPV17 Gene
This gene is overexpressed in Frontal cortex (6.5) and Monocytes (6.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for MPV17 Gene
NURSA nuclear receptor signaling pathways regulating expression of MPV17 Gene:
MPV17SOURCE GeneReport for Unigene cluster for MPV17 Gene:
Hs.75659mRNA Expression by UniProt/SwissProt for MPV17 Gene:
P39210-MPV17_HUMAN
Tissue specificity:
Ubiquitous. Expressed in pancreas, kidney, muscle, liver, lung, placenta, brain and heart.
Evidence on tissue expression from TISSUES for MPV17 Gene
- Liver(4.4)
- Skin(4.3)
- Nervous system(3.7)
- Muscle(2.4)
Phenotype-based relationships between genes and organs from Gene ORGANizer for MPV17 Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- cardiovascular
- digestive
- endocrine
- immune
- integumentary
- lymphatic
- nervous
- reproductive
- skeletal muscle
- skeleton
- urinary
Regions:
Head and neck:
- brain
- cerebellum
- cerebrospinal fluid
- ear
- eye
- head
- jaw
- mandible
- maxilla
- meninges
- mouth
- neck
- salivary gland
- skull
Thorax:
- breast
- chest wall
- clavicle
- esophagus
- heart
- rib
- rib cage
- scapula
- sternum
Abdomen:
- adrenal gland
- intestine
- kidney
- large intestine
- liver
- small intestine
- spleen
- stomach
Pelvis:
- pelvis
- testicle
Limb:
- ankle
- arm
- digit
- elbow
- femur
- fibula
- finger
- foot
- forearm
- hand
- hip
- humerus
- knee
- lower limb
- nail
- radius
- shin
- shoulder
- thigh
- tibia
- toe
- ulna
- upper limb
- wrist
General:
- blood
- blood vessel
- bone marrow
- coagulation system
- peripheral nerve
- peripheral nervous system
- skin
- spinal column
- spinal cord
- sweat gland
- vertebrae
- white blood cell
Primer Products
-
OriGene qPCR primer pairs for MPV17
-
OriGene qPCR primer pairs and template standards for MPV17
- genomics-online: primer clones - Search results for 90 available MPV17 gene related products
- Overview of 90 available MPV17 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for MPV17 Gene
Orthologs for MPV17 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | MPV17 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | MPV17 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | MPV17 34 33 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Mpv17l 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Mpv17 16 34 33 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | MPV17 34 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | MPV17 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | MPV17 34 33 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | mpv17 34 33 |
|
OneToOne | |
| -- 33 |
|
||||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP001778 33 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG11077 34 |
|
OneToOne | |
| worm (Caenorhabditis elegans) |
Secernentea | T18D3.9 34 33 |
|
OneToOne | |
| A. gosspyii yeast (Ashbya gossypii) |
Saccharomycetes | AGOS_AFR120C 33 |
|
||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | SYM1 36 34 33 |
|
||
| K. lactis yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0F22924g 33 |
|
||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | AT3G24570 33 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os01g0228300 33 |
|
||
| bread mold (Neurospora crassa) |
Ascomycetes | NCU02117 33 |
|
- Species where no ortholog for MPV17 was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
Evolution for MPV17 Gene
- ENSEMBL:
- Gene Tree for MPV17 (if available)
- TreeFam:
- Gene Tree for MPV17 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for MPV17: view image
Paralogs for MPV17 Gene
(3) SIMAP similar genes for MPV17 Gene using alignment to 14 proteins:
- MPV17_HUMAN
- A8MPV4_HUMAN
- A8MTD3_HUMAN
- B5MC10_HUMAN
- B5MC53_HUMAN
- B5MCF8_HUMAN
- C9J473_HUMAN
- D6W556_HUMAN
- E7EX18_HUMAN
- F8WEL3_HUMAN
- G5E9F5_HUMAN
- H0Y6M5_HUMAN
- H0Y7B6_HUMAN
- Q9UPC7_HUMAN
Variants for MPV17 Gene
| SNP ID | Clin | Chr 02 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs112170670 | uncertain-significance, Mitochondrial DNA depletion syndrome, Mitochondrial DNA depletion syndrome, hepatocerebral form | 27,312,496(-) | G/A | coding_sequence_variant, missense_variant | |
| rs121909721 | pathogenic, Navajo neurohepatopathy, Mitochondrial DNA depletion syndrome 6 (MTDPS6) [MIM:256810] | 27,313,031(-) | C/T | 5_prime_UTR_variant, coding_sequence_variant, missense_variant | |
| rs121909722 | pathogenic, Navajo neurohepatopathy, Mitochondrial DNA depletion syndrome 6 (MTDPS6) [MIM:256810] | 27,309,945(-) | G/T | coding_sequence_variant, missense_variant | |
| rs121909723 | pathogenic, Navajo neurohepatopathy, not provided, Mitochondrial DNA depletion syndrome 6 (MTDPS6) [MIM:256810] | 27,313,032(-) | G/A | 5_prime_UTR_variant, coding_sequence_variant, missense_variant | |
| rs121909724 | pathogenic, Navajo neurohepatopathy | 27,312,510(-) | C/T | coding_sequence_variant, stop_gained |
Residual Variation Intolerance Score:
73.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.69;
14.77% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for MPV17 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MPV17 Gene
Disorders for MPV17 Gene
(2) MalaCards diseases for MPV17 Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| mitochondrial dna depletion syndrome 6 |
|
|
| nephrotic syndrome |
|
Search MPV17 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
MPV17_HUMAN- Mitochondrial DNA depletion syndrome 6 (MTDPS6) [MIM:256810]: A disease due to mitochondrial dysfunction. It is characterized by infantile onset of progressive liver failure, often leading to death in the first year of life, peripheral neuropathy, corneal scarring, acral ulceration and osteomyelitis leading to autoamputation, cerebral leukoencephalopathy, failure to thrive, and recurrent metabolic acidosis with intercurrent infections. {ECO:0000269 PubMed:16582907, ECO:0000269 PubMed:16582910, ECO:0000269 PubMed:16909392, ECO:0000269 PubMed:20074988, ECO:0000269 PubMed:26741492}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for MPV17
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for Genatlas for MPV17 Gene
Publications for MPV17 Gene
- The human homolog of the glomerulosclerosis gene Mpv17: structure and genomic organization. (PMID: 8281143) Karasawa M … Weiher H (Human molecular genetics 1993) 2 3 4 22 58
- MPV17 encodes an inner mitochondrial membrane protein and is mutated in infantile hepatic mitochondrial DNA depletion. (PMID: 16582910) Spinazzola A … Zeviani M (Nature genetics 2006) 2 3 4 58
- Identification of rare DNA variants in mitochondrial disorders with improved array-based sequencing. (PMID: 20843780) Wang W … Scharfe C (Nucleic acids research 2011) 3 4 58
- Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson SL … O'Brien SJ (PloS one 2010) 3 44 58
- MPV17-associated hepatocerebral mitochondrial DNA depletion syndrome: new patients and novel mutations. (PMID: 20074988) El-Hattab AW … Wong LJ (Molecular genetics and metabolism 2010) 3 4 58
Products for MPV17 Gene
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- Novus Biologicals lysates and proteins for MPV17
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- Invitrogen Antibodies for MPV17 (AFLGC-MPV17)
- Cyagen custom Knockout/knockin (KOKI) mouse models for MPV17
- antibodies-online: Search results for 49 available MPV17 Antibodies ranked by validation data
- Compare Top MPV17 Antibodies
- antibodies-online: Search results for 4 available MPV17 Elisa Kits ranked by validation data
- Compare Top MPV17 Elisa Kits
- antibodies-online: Search results for 7 available MPV17 Proteins ranked by validation data
- Compare Top MPV17 Proteins
- GeneTex MPV17 Antibody for MPV17
- Search GeneTex for Proteins for MPV17
- Horizon Cell Lines for MPV17
- genomics-online: cdna clones - Search results for 90 available MPV17 gene related products
- Overview of 90 available MPV17 gene related products
- orf clones - Search results for 90 available MPV17 gene related products
- Overview of 90 available MPV17 gene related products
- genomics-online: gRNA clones - Search results for 90 available MPV17 gene related products
- Overview of 90 available MPV17 gene related products
- genomics-online: primer clones - Search results for 90 available MPV17 gene related products
- Overview of 90 available MPV17 gene related products
- genomics-online: shRNA clones - Search results for 90 available MPV17 gene related products
- Overview of 90 available MPV17 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MPV17
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MPV17
- GeneCopoeia miRNA 3'UTR Target clone products for MPV17
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MPV17
Sources for MPV17 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt