Aliases for MPPE1 Gene
External Ids for MPPE1 Gene
Previous GeneCards Identifiers for MPPE1 Gene
GeneCards Summary for MPPE1 Gene
MPPE1 (Metallophosphoesterase 1) is a Protein Coding gene. Diseases associated with MPPE1 include Multiple Congenital Anomalies-Hypotonia-Seizures Syndrome and Agnathia-Otocephaly Complex. Gene Ontology (GO) annotations related to this gene include hydrolase activity and phosphoric diester hydrolase activity.
UniProtKB/Swiss-Prot Summary for MPPE1 Gene
Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.