Aliases for MPP7 Gene
External Ids for MPP7 Gene
Previous GeneCards Identifiers for MPP7 Gene
The protein encoded by this gene is a member of the p55 Stardust family of membrane-associated guanylate kinase (MAGUK) proteins, which function in the establishment of epithelial cell polarity. This family member forms a complex with the polarity protein DLG1 (discs, large homolog 1) and facilitates epithelial cell polarity and tight junction formation. Polymorphisms in this gene are associated with variations in site-specific bone mineral density (BMD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
GeneCards Summary for MPP7 Gene
MPP7 (Membrane Palmitoylated Protein 7) is a Protein Coding gene. Diseases associated with MPP7 include Retinitis Pigmentosa 24. Gene Ontology (GO) annotations related to this gene include protein heterodimerization activity and protein complex scaffold activity. An important paralog of this gene is MPP3.
UniProtKB/Swiss-Prot for MPP7 Gene
Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact.