Aliases for MPLKIP Gene
External Ids for MPLKIP Gene
Previous HGNC Symbols for MPLKIP Gene
Previous GeneCards Identifiers for MPLKIP Gene
The protein encoded by this gene localizes to the centrosome during mitosis and to the midbody during cytokinesis. The protein is phosphorylated by cyclin-dependent kinase 1 during mitosis and subsequently interacts with polo-like kinase 1. The protein is thought to function in regulating mitosis and cytokinesis. Mutations in this gene result in nonphotosensitive trichothiodystrophy. [provided by RefSeq, Nov 2009]
GeneCards Summary for MPLKIP Gene
MPLKIP (M-Phase Specific PLK1 Interacting Protein) is a Protein Coding gene. Diseases associated with MPLKIP include Trichothiodystrophy 4, Nonphotosensitive and Trichothiodystrophy 1, Photosensitive.
UniProtKB/Swiss-Prot Summary for MPLKIP Gene
May play a role in maintenance of cell cycle integrity by regulating mitosis or cytokinesis.