Aliases for MPI Gene
Aliases for MPI Gene
External Ids for MPI Gene
- HGNC: 7216
- Entrez Gene: 4351
- Ensembl: ENSG00000178802
- OMIM: 154550
- UniProtKB: P34949
Previous GeneCards Identifiers for MPI Gene
- GC15U990034
- GC15P068297
- GC15P072758
- GC15P072898
- GC15P072969
- GC15P075182
- GC15P051979
Summaries for MPI Gene
-
Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
GeneCards Summary for MPI Gene
MPI (Mannose Phosphate Isomerase) is a Protein Coding gene. Diseases associated with MPI include Congenital Disorder Of Glycosylation, Type Ib and Protein-Losing Enteropathy. Among its related pathways are Fructose and mannose metabolism and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include mannose-6-phosphate isomerase activity.
UniProtKB/Swiss-Prot for MPI Gene
-
Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
Additional gene information for MPI Gene
- Monarch Initiative
- Search for MPI at DataMed
- Search for MPI at HumanCyc
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MPI Gene
Genomics for MPI Gene
GeneHancer (GH) Regulatory Elements for MPI Gene
Promoters and enhancers for MPI Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around MPI on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the MPI gene promoter:
-
- STAT1alpha
- RSRFC4
- STAT1
- CHOP-10
- STAT1beta
- STAT2
- STAT3
- STAT4
- STAT5A
- STAT5B
Regulatory Element Products
Genomic Locations for MPI Gene
Genomic Locations for MPI Gene
- chr15:74,890,005-74,902,219
- (GRCh38/hg38)
- Size:
- 12,215 bases
- Orientation:
- Plus strand
- chr15:75,182,346-75,191,798
- (GRCh37/hg19)
- Size:
- 9,453 bases
- Orientation:
- Plus strand
Genomic View for MPI Gene
Genes around MPI on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 15q24.1 by Entrez Gene
- 15q24.1 by HGNC
- 15q24.1 by Ensembl
MPI Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MPI Gene
Proteins for MPI Gene
-
Protein details for MPI Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P34949-MPI_HUMAN
- Recommended name:
- Mannose-6-phosphate isomerase
- Protein Accession:
- P34949
- A8K8K9
- Q96AB0
Protein attributes for MPI Gene
- Size:
- 423 amino acids
- Molecular mass:
- 46656 Da
- Cofactor:
- Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
- Quaternary structure:
- No Data Available
Protein Expression for MPI Gene
Post-translational modifications for MPI Gene
Other Protein References for MPI Gene
- ENSEMBL proteins:
-
- ENSP00000455477
- ENSP00000455972
- ENSP00000454622
- ENSP00000457020
- ENSP00000440447
- ENSP00000457885
- ENSP00000455241
- ENSP00000454619
- ENSP00000454312
- ENSP00000318318
- ENSP00000457494
- ENSP00000455405
- ENSP00000455161
- ENSP00000455065
- ENSP00000454267
- ENSP00000457619
- ENSP00000457013
- ENSP00000318192
- ENSP00000455383
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for MPI
-
Abcam antibodies for MPI
- Invitrogen Antibodies for MPI (AFLGC-MPI)
- GeneTex MPI Antibody for MPI
-
Boster Bio Antibodies for MPI
Protein Products
-
OriGene Purified Proteins for MPI
- Search Origene for MassSpec and Protein Over-expression Lysates for MPI
- Origene Custom Protein Services for MPI
- ProSpec Recombinant Proteins for MPI
- Search GeneTex for Proteins for MPI
-
Abcam proteins for MPI
No data available for DME Specific Peptides for MPI Gene
Domains & Families for MPI Gene
Gene Families for MPI Gene
- Human Protein Atlas (HPA):
-
- Disease related genes
- Enzymes
- Potential drug targets
- Predicted intracellular proteins
Protein Domains for MPI Gene
Suggested Antigen Peptide Sequences for MPI Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P34949- Family:
-
- Belongs to the mannose-6-phosphate isomerase type 1 family.
Function for MPI Gene
Molecular function for MPI Gene
- UniProtKB/Swiss-Prot Function:
- Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
- UniProtKB/Swiss-Prot CatalyticActivity:
- D-mannose 6-phosphate = D-fructose 6-phosphate.
- GENATLAS Biochemistry:
- mannose phosphate isomerase
Enzyme Numbers (IUBMB) for MPI Gene
Phenotypes From GWAS Catalog for MPI Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004476 | mannose-6-phosphate isomerase activity | TAS,IEA | -- |
| GO:0008270 | zinc ion binding | IEA | -- |
| GO:0016853 | isomerase activity | IEA | -- |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for MPI Gene
- MGI mutant phenotypes for MPI:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for MPI:
Animal Models for MPI Gene
- MGI Knock Outs for MPI:
-
- Mpi Mpi<tm1a(EUCOMM)Wtsi>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MPI
-
CRISPR Products
-
OriGene CRISPR knockouts for MPI
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MPI
- genomics-online: gRNA clones - Search results for available MPI gene related products
- Applied Biological Materials CRISPR for MPI
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for MPI
- GenScript: Design CRISPR guide RNA sequences for MPI
miRNA for MPI Gene
- miRTarBase miRNAs that target MPI
-
- hsa-mir-26b-5p (MIRT029256)
- hsa-mir-877-3p (MIRT036858)
- hsa-mir-877-5p (MIRT037312)
- hsa-mir-324-5p (MIRT043122)
- hsa-mir-320a (MIRT044606)
- hsa-mir-128-3p (MIRT783371)
- hsa-mir-216a-3p (MIRT784244)
- hsa-mir-221-5p (MIRT784261)
- hsa-mir-3681-3p (MIRT785228)
- hsa-mir-4786-5p (MIRT786767)
- hsa-mir-4793-5p (MIRT786805)
- hsa-mir-4794 (MIRT786809)
- hsa-mir-6502-3p (MIRT788233)
- hsa-mir-664a-5p (MIRT788428)
- hsa-mir-6771-3p (MIRT788639)
- hsa-mir-6801-5p (MIRT788817)
- hsa-mir-8073 (MIRT789805)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MPI
- Browse OriGene Inhibitory RNA Products For MPI
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MPI
- genomics-online: shRNA clones - Search results for available MPI gene related products
Clone Products
- Sino Biological Human cDNA Clone for MPI
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MPI
- genomics-online: cdna clones - Search results for available MPI gene related products
- orf clones - Search results for available MPI gene related products
- Applied Biological Materials Clones for MPI
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for MPI
No data available for Transcription Factor Targets and HOMER Transcription for MPI Gene
Localization for MPI Gene
Subcellular locations from UniProtKB/Swiss-Prot for MPI Gene
- Cytoplasm.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| cytosol | 5 |
| mitochondrion | 3 |
| nucleus | 2 |
| peroxisome | 1 |
- Cytosol (2)
- Plasma membrane (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IBA | -- |
| GO:0005829 | cytosol | TAS | -- |
| GO:0070062 | extracellular exosome | HDA | 23533145 |
Pathways & Interactions for MPI Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Fructose and mannose metabolism | ||
| 2 | Synthesis of substrates in N-glycan biosythesis | ||
| 3 | Metabolism of proteins | ||
| 4 | Amino sugar and nucleotide sugar metabolism | ||
| 5 | Metabolism | ||
Pathways by source for MPI Gene
2 BioSystems pathways for MPI Gene
3 KEGG pathways for MPI Gene
UniProtKB/Swiss-Prot P34949-MPI_HUMAN
- Pathway: Nucleotide-sugar biosynthesis; GDP-alpha-D-mannose biosynthesis; alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 1/2.
Interacting Proteins for MPI Gene
GPS-Prot Interaction Network for MPI
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000032 | cell wall mannoprotein biosynthetic process | IBA | -- |
| GO:0005975 | carbohydrate metabolic process | IEA | -- |
| GO:0006486 | protein glycosylation | IBA | -- |
| GO:0009298 | GDP-mannose biosynthetic process | TAS,IEA | -- |
| GO:0061611 | mannose to fructose-6-phosphate metabolic process | IEA | -- |
No data available for SIGNOR curated interactions for MPI Gene
Drugs & Compounds for MPI Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| Beta-D-Fructose 6-phosphate |
|
|
||||
| Fructose 6-phosphate |
|
643-13-0 |
|
Drug Products
Transcripts for MPI Gene
mRNA/cDNA for MPI Gene
- (7) REFSEQ mRNAs :
- (11) Additional mRNA sequences :
- (283) Selected AceView cDNA sequences:
- (24) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000569931 969 bps (uc059lmw.1)
- ENST00000352410 5828 bps (uc002azc.3)
- ENST00000566377 2809 bps (uc002azd.3)
- ENST00000569233 555 bps (uc059lmx.1)
- ENST00000567132 559 bps (uc059lmy.1)
Unigene Clusters for MPI Gene
- Mannose phosphate isomerase:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for MPI
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MPI
- genomics-online: gRNA clones - Search results for available MPI gene related products
- Applied Biological Materials CRISPR for MPI
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for MPI
- GenScript: Design CRISPR guide RNA sequences for MPI
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MPI
- Browse OriGene Inhibitory RNA Products For MPI
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MPI
- genomics-online: shRNA clones - Search results for available MPI gene related products
Clone Products
- Sino Biological Human cDNA Clone for MPI
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MPI
- genomics-online: cdna clones - Search results for available MPI gene related products
- orf clones - Search results for available MPI gene related products
- Applied Biological Materials Clones for MPI
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3a | · | 3b | · | 3c | · | 3d | · | 3e | ^ | 4a | · | 4b | · | 4c | · | 4d | · | 4e | ^ | 5a | · | 5b | · | 5c | · | 5d | · | 5e | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8a | · |
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| SP15: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP16: | - |
| ExUns: | 8b |
|---|---|
| SP1: | |
| SP2: | |
| SP3: | |
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| SP6: | |
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| SP16: |
Expression for MPI Gene
This gene is overexpressed in Salivary gland (7.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for MPI Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of MPI Gene:
MPISOURCE GeneReport for Unigene cluster for MPI Gene:
Hs.75694mRNA Expression by UniProt/SwissProt for MPI Gene:
P34949-MPI_HUMAN
Tissue specificity:
Expressed in all tissues, but more abundant in heart, brain and skeletal muscle.
Evidence on tissue expression from TISSUES for MPI Gene
- Nervous system(4.9)
- Blood(4.3)
- Liver(4.2)
- Intestine(2.4)
Phenotype-based relationships between genes and organs from Gene ORGANizer for MPI Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- cardiovascular
- digestive
- endocrine
- immune
- integumentary
- lymphatic
- nervous
- reproductive
- respiratory
- skeletal muscle
- urinary
Regions:
Head and neck:
- brain
- ear
- head
- mouth
- salivary gland
Thorax:
- breast
- esophagus
- heart
- lung
Abdomen:
- adrenal gland
- intestine
- kidney
- large intestine
- liver
- pancreas
- small intestine
- spleen
- stomach
Pelvis:
- testicle
Limb:
- digit
- finger
- foot
- hand
- lower limb
- nail
- toe
- upper limb
General:
- blood
- blood vessel
- coagulation system
- lymph node
- lymph vessel
- peripheral nerve
- peripheral nervous system
- skin
- sweat gland
- white blood cell
Primer Products
-
OriGene qPCR primer pairs for MPI
-
OriGene qPCR primer pairs and template standards for MPI
- genomics-online: primer clones - Search results for available MPI gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for MPI Gene
Orthologs for MPI Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | MPI 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | MPI 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | MPI 34 33 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Mpi 16 34 33 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Mpi 33 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | MPI 34 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | MPI 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | MPI 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | MPI 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | mpi 33 |
|
||
| Str.8465 33 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.4456 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | mpi 34 33 |
|
OneToOne | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP000053 33 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG8417 34 35 33 |
|
OneToOne | |
| worm (Caenorhabditis elegans) |
Secernentea | ZK632.4 34 35 33 |
|
OneToMany | |
| C05C8.7 34 35 |
|
OneToMany | |||
| A. gosspyii yeast (Ashbya gossypii) |
Saccharomycetes | AGOS_ADR003C 33 |
|
||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | PMI40 36 34 33 |
|
||
| K. lactis yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0D13728g 33 |
|
||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | DIN9 33 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os01g0127900 33 |
|
||
| Os.34778 33 |
|
||||
| bread mold (Neurospora crassa) |
Ascomycetes | NCU07165 33 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToOne | |
| fission yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | SPBC2G2.16 33 |
|
- Species where no ortholog for MPI was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Evolution for MPI Gene
- ENSEMBL:
- Gene Tree for MPI (if available)
- TreeFam:
- Gene Tree for MPI (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for MPI: view image
Paralogs for MPI Gene
No data available for Paralogs for MPI Gene
Variants for MPI Gene
| SNP ID | Clin | Chr 15 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs104894489 | conflicting-interpretations-of-pathogenicity, pathogenic, Congenital disorder of glycosylation type 1B, Congenital disorder of glycosylation, Congenital disorder of glycosylation 1B (CDG1B) [MIM:602579] | 74,893,306(+) | G/A | coding_sequence_variant, intron_variant, missense_variant | |
| rs104894494 | pathogenic, Congenital disorder of glycosylation type 1B, Congenital disorder of glycosylation 1B (CDG1B) [MIM:602579] | 74,891,539(+) | C/T | coding_sequence_variant, missense_variant | |
| rs104894495 | pathogenic, Congenital disorder of glycosylation type 1B, Congenital disorder of glycosylation 1B (CDG1B) [MIM:602579] | 74,892,728(+) | T/C | coding_sequence_variant, missense_variant | |
| rs1057516424 | likely-pathogenic, Congenital disorder of glycosylation type 1B | 74,893,302(+) | A/T | coding_sequence_variant, intron_variant, stop_gained | |
| rs1057516466 | likely-pathogenic, Congenital disorder of glycosylation type 1B | 74,890,630(+) | C/ | coding_sequence_variant, frameshift, intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv1060905 | CNV | insertion | 17803354 |
| esv990390 | CNV | deletion | 20482838 |
| nsv1121512 | CNV | deletion | 24896259 |
Residual Variation Intolerance Score:
64.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.21;
39.83% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for MPI Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MPI Gene
Disorders for MPI Gene
(6) MalaCards diseases for MPI Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| congenital disorder of glycosylation, type ib |
|
|
| protein-losing enteropathy |
|
|
| congenital disorder of glycosylation, type in |
|
|
| onchocerciasis |
|
|
| leishmaniasis |
|
Search MPI in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
MPI_HUMAN- Congenital disorder of glycosylation 1B (CDG1B) [MIM:602579]: A form of congenital disorder of glycosylation, a multisystem disorder caused by a defect in glycoprotein biosynthesis and characterized by under-glycosylated serum glycoproteins. Congenital disorders of glycosylation result in a wide variety of clinical features, such as defects in the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions. CDG1B is clinically characterized by protein-losing enteropathy. {ECO:0000269 PubMed:10980531, ECO:0000269 PubMed:11134235, ECO:0000269 PubMed:11350186, ECO:0000269 PubMed:12357336, ECO:0000269 PubMed:12414827, ECO:0000269 PubMed:9525984, ECO:0000269 PubMed:9585601}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for MPI
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for Genatlas for MPI Gene
Publications for MPI Gene
- DHPLC analysis as a platform for molecular diagnosis of congenital disorders of glycosylation (CDG). (PMID: 12357336) Schollen E … Matthijs G (European journal of human genetics : EJHG 2002) 3 4 22 58
- Genetic and metabolic analysis of the first adult with congenital disorder of glycosylation type Ib: long-term outcome and effects of mannose supplementation. (PMID: 11350186) Westphal V … Freeze HH (Molecular genetics and metabolism 2001) 3 4 22 58
- Genomic organization of the human phosphomannose isomerase (MPI) gene and mutation analysis in patients with congenital disorders of glycosylation type Ib (CDG-Ib). (PMID: 10980531) Schollen E … Matthijs G (Human mutation 2000) 3 4 22 58
- Carbohydrate-deficient glycoprotein syndrome type Ib. Phosphomannose isomerase deficiency and mannose therapy. (PMID: 9525984) Niehues R … Marquardt T (The Journal of clinical investigation 1998) 3 4 22 58
- Purification, cDNA cloning and heterologous expression of human phosphomannose isomerase. (PMID: 8307007) Proudfoot AE … Smith DJ (European journal of biochemistry 1994) 3 4 22 58
Products for MPI Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Human Proteins and Enzymes
- Browse Primary Antibodies
- Browse Proteins and Enzymes
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- Custom Antibody ServicesOriGene Antibodies for MPI
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- GenScript: Next-day shipping of latest version cDNA ORF clones for MPI in any vector
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- CloneReady with Over 120,000 Genes
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- antibodies-online: Search results for 87 available MPI Antibodies ranked by validation data
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- GeneTex MPI Antibody for MPI
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Sources for MPI Gene
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- (68) Cloud-Clone Corp.
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