Aliases for MOV10 Gene
Aliases for MOV10 Gene
External Ids for MOV10 Gene
- HGNC: 7200
- Entrez Gene: 4343
- Ensembl: ENSG00000155363
- OMIM: 610742
- UniProtKB: Q9HCE1
Previous GeneCards Identifiers for MOV10 Gene
- GC01P113631
- GC01P112101
- GC01P112319
- GC01P112516
- GC01P112929
- GC01P113018
- GC01P113215
- GC01P111075
Summaries for MOV10 Gene
GeneCards Summary for MOV10 Gene
MOV10 (Mov10 RISC Complex RNA Helicase) is a Protein Coding gene. Among its related pathways are RET signaling and Innate Immune System. Gene Ontology (GO) annotations related to this gene include helicase activity. An important paralog of this gene is MOV10L1.
UniProtKB/Swiss-Prot for MOV10 Gene
-
Probable RNA helicase. Required for miRNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC.
-
(Microbial infection) Required for RNA-directed transcription and replication of the human hepatitis delta virus (HDV). Interacts with small capped HDV RNAs derived from genomic hairpin structures that mark the initiation sites of RNA-dependent HDV RNA transcription.
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MOV10 Gene
Genomics for MOV10 Gene
GeneHancer (GH) Regulatory Elements for MOV10 Gene
Promoters and enhancers for MOV10 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around MOV10 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the MOV10 gene promoter:
Regulatory Element Products
Genomic Locations for MOV10 Gene
Genomic Locations for MOV10 Gene
- chr1:112,673,141-112,700,746
- (GRCh38/hg38)
- Size:
- 27,606 bases
- Orientation:
- Plus strand
- chr1:113,215,763-113,243,368
- (GRCh37/hg19)
Genomic View for MOV10 Gene
Genes around MOV10 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p13.2 by Ensembl
- 1p13.2 by Entrez Gene
- 1p13.2 by HGNC
MOV10 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MOV10 Gene
Proteins for MOV10 Gene
-
Protein details for MOV10 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9HCE1-MOV10_HUMAN
- Recommended name:
- Putative helicase MOV-10
- Protein Accession:
- Q9HCE1
- Q5JR03
- Q8TEF0
- Q9BSY3
- Q9BUJ9
Protein attributes for MOV10 Gene
- Size:
- 1003 amino acids
- Molecular mass:
- 113671 Da
- Quaternary structure:
-
- Interacts with DICER1, AGO2, TARBP2, EIF6 and RPL7A (60S ribosome subunit); they form a large RNA-induced silencing complex (RISC) (PubMed:17507929). Interacts with APOBEC3G in an RNA-dependent manner. Interacts with TRIM71 (via NHL repeats) in an RNA-dependent manner (PubMed:23125361).
- (Microbial infection) Interacts with the human hepatitis delta virus (HDV) antigen HDAg.
- SequenceCaution:
-
- Sequence=BAB13457.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305}; Sequence=BAB85000.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
Protein Expression for MOV10 Gene
Selected DME Specific Peptides for MOV10 Gene
- Q9HCE1:
-
- VLAGDPRQLGPV
- QFITKLL
- PIIFHGV
- GQLVLAGDP
- GPPGTGKTV
- PYRKQVEKI
- LGFLKNPKR
Post-translational modifications for MOV10 Gene
Other Protein References for MOV10 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for MOV10
- Novus Biologicals Antibodies for MOV10
-
Abcam antibodies for MOV10
- Invitrogen Antibodies for MOV10
- GeneTex MOV10 antibody for MOV10
-
Santa Cruz Biotechnology (SCBT) Antibodies for MOV10
Protein Products
-
OriGene Purified Proteins for MOV10
- Search Origene for MassSpec and Protein Over-expression Lysates for MOV10
- Origene Custom Protein Services for MOV10
- Search GeneTex for Proteins for MOV10
Assay Products
Domains & Families for MOV10 Gene
Gene Families for MOV10 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Enzymes
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for MOV10 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for MOV10 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9HCE1- Family:
-
- Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
Function for MOV10 Gene
Molecular function for MOV10 Gene
- UniProtKB/Swiss-Prot CatalyticActivity:
- ATP + H(2)O = ADP + phosphate.
- UniProtKB/Swiss-Prot Function:
- Probable RNA helicase. Required for miRNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC.
- UniProtKB/Swiss-Prot Function:
- (Microbial infection) Required for RNA-directed transcription and replication of the human hepatitis delta virus (HDV). Interacts with small capped HDV RNAs derived from genomic hairpin structures that mark the initiation sites of RNA-dependent HDV RNA transcription.
Enzyme Numbers (IUBMB) for MOV10 Gene
Phenotypes From GWAS Catalog for MOV10 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003723 | RNA binding | HDA,IEA | 22658674 |
| GO:0004386 | helicase activity | IEA | -- |
| GO:0005515 | protein binding | IPI | 16289642 |
| GO:0005524 | ATP binding | IEA | -- |
| GO:0016787 | hydrolase activity | IEA | -- |
Phenotypes for MOV10 Gene
- GenomeRNAi human phenotypes for MOV10:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MOV10
-
-
ViGene Biosciences lentiviral particle packaged cDNA for MOV10 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for MOV10 gene
- Search ViGene Biosciences for MOV10
CRISPR Products
-
OriGene CRISPR knockouts for MOV10
- genomics-online: gRNA clones - Search results for 124 available MOV10 gene related products
- Overview of 124 available MOV10 gene related products
- Applied Biological Materials CRISPR for MOV10
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for MOV10
- GenScript: Design CRISPR guide RNA sequences for MOV10
miRNA for MOV10 Gene
- miRTarBase miRNAs that target MOV10
miRNA Products
- Search ViGene Biosciences for MOV10
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MOV10
- Browse OriGene Inhibitory RNA Products For MOV10
- genomics-online: shRNA clones - Search results for 124 available MOV10 gene related products
- Overview of 124 available MOV10 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for MOV10 gene
Clone Products
- Sino Biological Human cDNA Clone for MOV10
- VectorBuilder custom plasmid, inducible vectors for MOV10
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MOV10
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for MOV10
- Applied Biological Materials Clones for MOV10
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for MOV10
-
ViGene Biosciences adenoviral particle packaged cDNA for MOV10 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for MOV10 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for MOV10 gene
No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MOV10 Gene
Localization for MOV10 Gene
Subcellular locations from UniProtKB/Swiss-Prot for MOV10 Gene
- Cytoplasm, P-body.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| cytosol | 5 |
| nucleus | 2 |
| mitochondrion | 1 |
| peroxisome | 1 |
- Cytosol (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000932 | P-body | IEA,IDA | 16289642 |
| GO:0005615 | extracellular space | HDA,IDA | 22664934 |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | TAS | -- |
Pathways & Interactions for MOV10 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | RET signaling |
.92
|
|
| 2 | PI3K/AKT activation |
.89
|
|
| 3 | CDK-mediated phosphorylation and removal of Cdc6 |
.41
|
|
| 4 | Cellular Senescence (REACTOME) | ||
| 5 | Downstream signaling events of B Cell Receptor (BCR) | ||
Pathways by source for MOV10 Gene
35 Reactome pathways for MOV10 Gene
Interacting Proteins for MOV10 Gene
Selected Interacting proteins:
ENSP00000350028
Q9HCE1-MOV10_HUMAN
for MOV10 Gene via
STRING
MINT
UniProtKB
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0007223 | Wnt signaling pathway, calcium modulating pathway | TAS | -- |
| GO:0031047 | gene silencing by RNA | IEA | -- |
| GO:0035195 | gene silencing by miRNA | IMP | 17507929 |
No data available for SIGNOR curated interactions for MOV10 Gene
Drugs & Compounds for MOV10 Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| ADP |
|
Full agonist, Agonist | 58-64-0 |
|
Transcripts for MOV10 Gene
mRNA/cDNA for MOV10 Gene
- (8) REFSEQ mRNAs :
- (15) Additional mRNA sequences :
- (363) Selected AceView cDNA sequences:
- (17) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for MOV10 Gene
CRISPR Products
-
OriGene CRISPR knockouts for MOV10
- genomics-online: gRNA clones - Search results for 124 available MOV10 gene related products
- Overview of 124 available MOV10 gene related products
- Applied Biological Materials CRISPR for MOV10
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for MOV10
- GenScript: Design CRISPR guide RNA sequences for MOV10
miRNA Products
- Search ViGene Biosciences for MOV10
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MOV10
- Browse OriGene Inhibitory RNA Products For MOV10
- genomics-online: shRNA clones - Search results for 124 available MOV10 gene related products
- Overview of 124 available MOV10 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for MOV10 gene
Clone Products
- Sino Biological Human cDNA Clone for MOV10
- VectorBuilder custom plasmid, inducible vectors for MOV10
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MOV10
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for MOV10
- Applied Biological Materials Clones for MOV10
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | · | 3c | · | 3d | · | 3e | · | 3f | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | · | 9c | ^ | 10a | · | 10b | · | 10c | ^ | 11a | · | 11b | · | 11c | · | 11d | · |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
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| SP8: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP10: | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP11: | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP12: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP13: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP14: | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP15: | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP16: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP17: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP18: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||
| SP19: | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP20: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP21: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP22: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP23: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP24: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP25: | - | - | - | - | - | - | - | - | - | - | - |
| ExUns: | 11e | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16a | · | 16b | ^ | 17 | ^ | 18a | · | 18b | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22a | · | 22b | · | 22c | ^ | 23 | ^ | 24a | · | 24b | · | 24c | ^ | 25a | · | 25b | · | 25c | · | 25d | ^ | 26a | · |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP12: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP13: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP14: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP15: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP16: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP17: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP18: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP19: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP20: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP21: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP22: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP23: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP24: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP25: |
| ExUns: | 26b | ^ | 27a | · | 27b | ^ | 28 | ^ | 29a | · | 29b |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||
| SP2: | - | ||||||||||
| SP3: | - | ||||||||||
| SP4: | |||||||||||
| SP5: | |||||||||||
| SP6: | |||||||||||
| SP7: | |||||||||||
| SP8: | |||||||||||
| SP9: | |||||||||||
| SP10: | |||||||||||
| SP11: | |||||||||||
| SP12: | |||||||||||
| SP13: | |||||||||||
| SP14: | |||||||||||
| SP15: | |||||||||||
| SP16: | |||||||||||
| SP17: | |||||||||||
| SP18: | |||||||||||
| SP19: | |||||||||||
| SP20: | |||||||||||
| SP21: | |||||||||||
| SP22: | |||||||||||
| SP23: | |||||||||||
| SP24: | |||||||||||
| SP25: |
Expression for MOV10 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Placenta (Extraembryonic Tissues)
- Primordial Germ Cells Allantois
-
Gonad
- Primordial Germ Cells Allantois
This gene is overexpressed in Bone marrow stromal cell (13.5) and Fetal Liver (7.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for MOV10 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of MOV10 Gene:
MOV10SOURCE GeneReport for Unigene cluster for MOV10 Gene:
Hs.514941Evidence on tissue expression from TISSUES for MOV10 Gene
- Nervous system(4.8)
- Lung(4.5)
- Liver(4.4)
- Skin(4.3)
- Spleen(4.3)
- Muscle(4.2)
Primer Products
-
OriGene qPCR primer pairs and template standards for MOV10
-
OriGene qPCR primer pairs for MOV10
- genomics-online: primer clones - Search results for 124 available MOV10 gene related products
- Overview of 124 available MOV10 gene related products
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for MOV10 Gene
Orthologs for MOV10 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | MOV10 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | MOV10 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | MOV10 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Mov10 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Mov10 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | MOV10 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | MOV10 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | MOV10 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | mov10 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | mov10a 34 |
|
OneToMany | |
| mov10b.1 34 |
|
OneToMany | |||
| mov10b.2 34 |
|
OneToMany | |||
| Dr.12042 33 |
|
||||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.12854 33 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG6967 35 34 |
|
||
| CG11513 35 |
|
|
|||
| CG6701 35 |
|
|
|||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | NAM7 34 |
|
OneToMany | |
| thale cress (Arabidopsis thaliana) |
eudicotyledons | SDE3 33 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os03g0160400 33 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToOne |
- Species where no ortholog for MOV10 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for MOV10 Gene
Variants for MOV10 Gene
| SNP ID | Clin | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000004804 | -- | 112,687,856(+) | G/T | intron_variant | |
| rs1000016671 | -- | 112,692,915(+) | C/T | coding_sequence_variant, non_coding_transcript_variant, synonymous_variant | |
| rs1000114216 | -- | 112,701,137(+) | C/T | 3_prime_UTR_variant, downstream_transcript_variant, genic_downstream_transcript_variant | |
| rs1000126367 | -- | 112,684,181(+) | C/G | intron_variant | |
| rs1000299807 | -- | 112,672,644(+) | G/A | upstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv27061 | CNV | gain+loss | 19812545 |
| esv3587217 | CNV | loss | 21293372 |
| esv997362 | CNV | deletion | 20482838 |
| nsv1133888 | CNV | deletion | 24896259 |
Residual Variation Intolerance Score:
7.96% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.63;
31.29% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for MOV10 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MOV10 Gene
Disorders for MOV10 Gene
Additional Disease Information for MOV10
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for MOV10 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MOV10 Gene
Publications for MOV10 Gene
- The mammalian TRIM-NHL protein TRIM71/LIN-41 is a repressor of mRNA function. (PMID: 23125361) Loedige I … Filipowicz W (Nucleic acids research 2013) 3 4 58
- APOBEC3G inhibits microRNA-mediated repression of translation by interfering with the interaction between Argonaute-2 and MOV10. (PMID: 22791714) Liu C … Zhang H (The Journal of biological chemistry 2012) 3 4 58
- Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. (PMID: 21909110) Wain LV … van Duijn CM (Nature genetics 2011) 3 44 58
- Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. (PMID: 21909115) International Consortium for Blood Pressure Genome-Wide Association Studies … Johnson T (Nature 2011) 3 44 58
- Capped small RNAs and MOV10 in human hepatitis delta virus replication. (PMID: 18552826) Haussecker D … Kay MA (Nature structural & molecular biology 2008) 3 4 58
Products for MOV10 Gene
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- Custom Antibody ServicesOriGene Antibodies for MOV10
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- Sino Biological Human cDNA Clone for MOV10
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- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Cyagen custom Knockout/knockin (KOKI) mouse models for MOV10
- VectorBuilder custom plasmid, inducible vectors for MOV10
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MOV10
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for MOV10
- antibodies-online: Search results for 36 available MOV10 Antibodies ranked by validation data
- Compare Top MOV10 Antibodies
- antibodies-online: Search results for available MOV10 related products ranked by validation data
- antibodies-online: Search results for 3 available MOV10 Proteins ranked by validation data
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- GeneTex MOV10 antibody for MOV10
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- ViGene Biosciences adenoviral particle packaged cDNA for MOV10 gene
- ViGene Biosciences lentiviral particle packaged cDNA for MOV10 gene
- ViGene Biosciences ready-to-package AAV shRNAs for MOV10 gene
- Search ViGene Biosciences for MOV10
- Santa Cruz Biotechnology (SCBT) Antibodies for MOV10
- Search Santa Cruz Biotechnology (SCBT) for MOV10 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for MOV10
- Horizon Cell Lines for MOV10
- genomics-online: cdna clones - Search results for 124 available MOV10 gene related products
- Overview of 124 available MOV10 gene related products
- orf clones - Search results for 124 available MOV10 gene related products
- Overview of 124 available MOV10 gene related products
- genomics-online: gRNA clones - Search results for 124 available MOV10 gene related products
- Overview of 124 available MOV10 gene related products
- genomics-online: primer clones - Search results for 124 available MOV10 gene related products
- Overview of 124 available MOV10 gene related products
- genomics-online: shRNA clones - Search results for 124 available MOV10 gene related products
- Overview of 124 available MOV10 gene related products
Sources for MOV10 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
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- (128) ViGene Biosciences
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- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
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- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
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- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems