Aliases for MOV10 Gene

Aliases for MOV10 Gene

  • Mov10 RISC Complex RNA Helicase 2 3 5
  • Functional Spliceosome-Associated Protein 113 2 3
  • Moloney Leukemia Virus 10 Protein 3 4
  • Armitage Homolog 3 4
  • Helicase MOV-10 3 4
  • FSAP113 2 3
  • Gb110 2 3
  • Mov10, Moloney Leukemia Virus 10, Homolog (Mouse) 2
  • Mov10 (Moloney Leukemia Virus 10, Mouse) Homolog 2
  • Mov10, Moloney Leukemia Virus 10, Homolog 3
  • Putative Helicase MOV-10 3
  • EC 3.6.4.13 4
  • KIAA1631 4
  • EC 3.6.1 51
  • MGC2948 2
  • MOV10 5

External Ids for MOV10 Gene

Previous GeneCards Identifiers for MOV10 Gene

  • GC01P113631
  • GC01P112101
  • GC01P112319
  • GC01P112516
  • GC01P112929
  • GC01P113018
  • GC01P113215
  • GC01P111075

Summaries for MOV10 Gene

GeneCards Summary for MOV10 Gene

MOV10 (Mov10 RISC Complex RNA Helicase) is a Protein Coding gene. Diseases associated with MOV10 include Autism Spectrum Disorder. Among its related pathways are RET signaling and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include helicase activity. An important paralog of this gene is MOV10L1.

UniProtKB/Swiss-Prot Summary for MOV10 Gene

  • 5' to 3' RNA helicase contributing to UPF1 mRNA target degradation by translocation along 3' UTRs (PubMed:24726324). Required for microRNA (miRNA)-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC (PubMed:16289642, PubMed:17507929, PubMed:22791714). In cooperation with FMR1, regulates miRNA-mediated translational repression by AGO2 (PubMed:25464849). Restricts retrotransposition of long interspersed element-1 (LINE-1) in cooperation with TUT4 and TUT7 counteracting the RNA chaperonne activity of L1RE1 (PubMed:30122351, PubMed:23093941). Facilitates LINE-1 uridylation by TUT4 and TUT7 (PubMed:30122351). Required for embryonic viability and for normal central nervous system development and function. Plays two critical roles in early brain development: suppresses retroelements in the nucleus by directly inhibiting cDNA synthesis, while regulates cytoskeletal mRNAs to influence neurite outgrowth in the cytosol (By similarity). May function as a messenger ribonucleoprotein (mRNP) clearance factor (PubMed:24726324). Exhibits antiviral activity against dengue virus (DENV) (PubMed:27974568).
  • (Microbial infection) Required for RNA-directed transcription and replication of the human hepatitis delta virus (HDV). Interacts with small capped HDV RNAs derived from genomic hairpin structures that mark the initiation sites of RNA-dependent HDV RNA transcription.

Gene Wiki entry for MOV10 Gene

Additional gene information for MOV10 Gene

No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MOV10 Gene

Genomics for MOV10 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MOV10 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MOV10 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for MOV10

Top Transcription factor binding sites by QIAGEN in the MOV10 gene promoter:
  • COUP
  • COUP-TF
  • COUP-TF1
  • HNF-4alpha1
  • HNF-4alpha2
  • Lmo2
  • POU3F2
  • POU3F2 (N-Oct-5a)
  • POU3F2 (N-Oct-5b)
  • Zic1

Genomic Locations for MOV10 Gene

Genomic Locations for MOV10 Gene
chr1:112,673,141-112,702,377
(GRCh38/hg38)
Size:
29,237 bases
Orientation:
Plus strand
chr1:113,215,763-113,243,368
(GRCh37/hg19)
Size:
27,606 bases
Orientation:
Plus strand

Genomic View for MOV10 Gene

Genes around MOV10 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MOV10 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MOV10 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MOV10 Gene

Proteins for MOV10 Gene

  • Protein details for MOV10 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9HCE1-MOV10_HUMAN
    Recommended name:
    Helicase MOV-10
    Protein Accession:
    Q9HCE1
    Secondary Accessions:
    • Q5JR03
    • Q8TEF0
    • Q9BSY3
    • Q9BUJ9

    Protein attributes for MOV10 Gene

    Size:
    1003 amino acids
    Molecular mass:
    113671 Da
    Quaternary structure:
    • Interacts with DICER1, AGO2, TARBP2, EIF6 and RPL7A (60S ribosome subunit); they form a large RNA-induced silencing complex (RISC) (PubMed:17507929). Interacts with APOBEC3G in an RNA-dependent manner. Interacts with TRIM71 (via NHL repeats) in an RNA-dependent manner (PubMed:23125361). Interacts with both protein products of LIRE1, ORF1p and ORF2p (PubMed:23093941). Interacts with TUT4 and, to a lesser extent, TUT7; the interactions are RNA-dependent (PubMed:30122351). Interacts with AGO2, TNRC6B and UPF1; the interactions are direct and RNA-dependent (PubMed:24726324). Interacts with FMR1; this interaction is direct, occurs in an RNA-dependent manner on polysomes and induces association of MOV10 with RNAs (PubMed:25464849). Interacts with SHFL; the interaction increases in presence of RNA (PubMed:27974568).
    • (Microbial infection) Interacts with the human hepatitis delta virus (HDV) antigen HDAg.
    SequenceCaution:
    • Sequence=BAB13457.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305}; Sequence=BAB85000.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};

    Alternative splice isoforms for MOV10 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MOV10 Gene

Selected DME Specific Peptides for MOV10 Gene

Q9HCE1:
  • VLAGDPRQLGPV
  • QFITKLL
  • PIIFHGV
  • GQLVLAGDP
  • GPPGTGKTV
  • PYRKQVEKI
  • LGFLKNPKR

Post-translational modifications for MOV10 Gene

  • Ubiquitination at Lys109, Lys121, Lys281, Lys489, Lys530, Lys547, Lys602, Lys695, Lys727, Lys846, Lys858, and Lys967
  • Modification sites at PhosphoSitePlus

Domains & Families for MOV10 Gene

Gene Families for MOV10 Gene

HGNC:
Human Protein Atlas (HPA):
  • Enzymes
  • Plasma proteins
  • Predicted intracellular proteins

Protein Domains for MOV10 Gene

Suggested Antigen Peptide Sequences for MOV10 Gene

GenScript: Design optimal peptide antigens:
  • Moloney leukemia virus 10 protein (MOV10_HUMAN)
  • cDNA FLJ13235 fis, clone OVARC1000304, highly similar to PROTEIN MOV-10 (Q9H8T8_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q9HCE1

UniProtKB/Swiss-Prot:

MOV10_HUMAN :
  • Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
Family:
  • Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
genes like me logo Genes that share domains with MOV10: view

Function for MOV10 Gene

Molecular function for MOV10 Gene

UniProtKB/Swiss-Prot Function:
5' to 3' RNA helicase contributing to UPF1 mRNA target degradation by translocation along 3' UTRs (PubMed:24726324). Required for microRNA (miRNA)-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC (PubMed:16289642, PubMed:17507929, PubMed:22791714). In cooperation with FMR1, regulates miRNA-mediated translational repression by AGO2 (PubMed:25464849). Restricts retrotransposition of long interspersed element-1 (LINE-1) in cooperation with TUT4 and TUT7 counteracting the RNA chaperonne activity of L1RE1 (PubMed:30122351, PubMed:23093941). Facilitates LINE-1 uridylation by TUT4 and TUT7 (PubMed:30122351). Required for embryonic viability and for normal central nervous system development and function. Plays two critical roles in early brain development: suppresses retroelements in the nucleus by directly inhibiting cDNA synthesis, while regulates cytoskeletal mRNAs to influence neurite outgrowth in the cytosol (By similarity). May function as a messenger ribonucleoprotein (mRNP) clearance factor (PubMed:24726324). Exhibits antiviral activity against dengue virus (DENV) (PubMed:27974568).
UniProtKB/Swiss-Prot Function:
(Microbial infection) Required for RNA-directed transcription and replication of the human hepatitis delta virus (HDV). Interacts with small capped HDV RNAs derived from genomic hairpin structures that mark the initiation sites of RNA-dependent HDV RNA transcription.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13; Evidence={ECO:0000269|PubMed:24726324};.

Enzyme Numbers (IUBMB) for MOV10 Gene

Phenotypes From GWAS Catalog for MOV10 Gene

Gene Ontology (GO) - Molecular Function for MOV10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0003723 RNA binding IBA,IDA 23093941
GO:0003724 RNA helicase activity IEA --
GO:0004386 helicase activity IEA --
GO:0005515 protein binding IPI 16289642
genes like me logo Genes that share ontologies with MOV10: view
genes like me logo Genes that share phenotypes with MOV10: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MOV10

Clone Products

  • Addgene plasmids for MOV10

No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MOV10 Gene

Localization for MOV10 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MOV10 Gene

Cytoplasm, P-body. Cytoplasm, Cytoplasmic ribonucleoprotein granule. Cytoplasm, Stress granule. Nucleus. Cytoplasm. Note=Co-enriched in cytoplasmic foci with TUT4 (PubMed:30122351). In developing neurons, localizes both in nucleus and cytoplasm, but in the adulthood it is only cytoplasmic (By similarity). After infection, relocalizes to the DENV replication complex in perinuclear regions (PubMed:27974568). {ECO:0000250 UniProtKB:P23249, ECO:0000269 PubMed:27974568, ECO:0000269 PubMed:30122351}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MOV10 gene
Compartment Confidence
nucleus 5
extracellular 4
cytosol 4
plasma membrane 1
cytoskeleton 1
mitochondrion 1
peroxisome 1
endoplasmic reticulum 1
endosome 1
lysosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for MOV10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000932 P-body IEA,IDA 16289642
GO:0005615 extracellular space HDA 22664934
GO:0005634 nucleus ISS --
GO:0005737 cytoplasm IEA --
GO:0005829 cytosol TAS --
genes like me logo Genes that share ontologies with MOV10: view

Pathways & Interactions for MOV10 Gene

genes like me logo Genes that share pathways with MOV10: view

SIGNOR curated interactions for MOV10 Gene

Activates:

Gene Ontology (GO) - Biological Process for MOV10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007223 Wnt signaling pathway, calcium modulating pathway TAS --
GO:0010526 negative regulation of transposition, RNA-mediated IDA 23093941
GO:0010628 positive regulation of gene expression TAS --
GO:0010629 negative regulation of gene expression TAS --
GO:0016032 viral process IEA --
genes like me logo Genes that share ontologies with MOV10: view

Drugs & Compounds for MOV10 Gene

(3) Drugs for MOV10 Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Phosphoric acid Approved Pharma 0
Water Approved Pharma 0
ATP Investigational Nutra Agonist, Activator, Partial agonist, Antagonist, Full agonist, Gating inhibitor, Pore Blocker, Potentiation 0

(1) Additional Compounds for MOV10 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
ADP
  • 5'-Adenylphosphoric acid
  • Adenosine 5'-diphosphate
  • ADENOSINE-5'-diphosphATE
  • H3ADP
  • 5'-Adenylphosphate
Agonist, Full agonist, Partial agonist, Gating inhibitor, Antagonist 58-64-0
genes like me logo Genes that share compounds with MOV10: view

Transcripts for MOV10 Gene

mRNA/cDNA for MOV10 Gene

5 REFSEQ mRNAs :
17 NCBI additional mRNA sequence :
17 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MOV10

Clone Products

  • Addgene plasmids for MOV10

Alternative Splicing Database (ASD) splice patterns (SP) for MOV10 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c · 3d · 3e · 3f ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b · 9c ^ 10a · 10b · 10c ^ 11a · 11b · 11c · 11d ·
SP1: - - - - - - - - -
SP2: - - - -
SP3: - - - -
SP4: - - - - - - - -
SP5:
SP6:
SP7:
SP8: - - - - - - -
SP9: - - - - - - - - - - -
SP10: - - - - - - - - -
SP11: - - - - - - - - - -
SP12: - - - - - - - -
SP13: - - - - - -
SP14: - - - - - - - - - -
SP15: - - - - - - - - - - - -
SP16: - - - - - - -
SP17: - - - - - -
SP18: - - - - - - - - - - - - - - - - -
SP19: - - - - - - - - - - -
SP20:
SP21: - - - - - - -
SP22: - - - - - - -
SP23: -
SP24:
SP25: - - - - - - - - - - -

ExUns: 11e ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16a · 16b ^ 17 ^ 18a · 18b ^ 19 ^ 20 ^ 21 ^ 22a · 22b · 22c ^ 23 ^ 24a · 24b · 24c ^ 25a · 25b · 25c · 25d ^ 26a ·
SP1: - - - - -
SP2: - - - - -
SP3: - - - -
SP4: -
SP5: - - - -
SP6: - - -
SP7: -
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:
SP18: -
SP19:
SP20:
SP21:
SP22:
SP23:
SP24: -
SP25:

ExUns: 26b ^ 27a · 27b ^ 28 ^ 29a · 29b
SP1: -
SP2: -
SP3: -
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:
SP18:
SP19:
SP20:
SP21:
SP22:
SP23:
SP24:
SP25:

Relevant External Links for MOV10 Gene

GeneLoc Exon Structure for
MOV10

Expression for MOV10 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MOV10 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for MOV10 Gene

This gene is overexpressed in Bone marrow stromal cell (13.5) and Fetal Liver (7.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for MOV10 Gene



Protein tissue co-expression partners for MOV10 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MOV10

SOURCE GeneReport for Unigene cluster for MOV10 Gene:

Hs.514941

Evidence on tissue expression from TISSUES for MOV10 Gene

  • Nervous system(4.8)
  • Lung(4.6)
  • Skin(4.5)
  • Liver(4.5)
  • Spleen(4.4)
  • Muscle(4.4)
  • Kidney(2.4)
  • Intestine(2.2)
genes like me logo Genes that share expression patterns with MOV10: view

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for MOV10 Gene

Orthologs for MOV10 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for MOV10 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia MOV10 30 31
  • 99.53 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia MOV10 30 31
  • 90.46 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia MOV10 30 31
  • 90.33 (n)
OneToOne
Mouse
(Mus musculus)
Mammalia Mov10 30 17 31
  • 88.04 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Mov10 30
  • 87.8 (n)
Oppossum
(Monodelphis domestica)
Mammalia MOV10 31
  • 63 (a)
OneToOne
Chicken
(Gallus gallus)
Aves MOV10 30 31
  • 58.69 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia MOV10 31
  • 47 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia mov10 30
  • 54.43 (n)
Zebrafish
(Danio rerio)
Actinopterygii mov10a 31
  • 44 (a)
OneToMany
mov10b.1 31
  • 43 (a)
OneToMany
mov10b.2 31
  • 43 (a)
OneToMany
Dr.12042 30
Rainbow Trout
(Oncorhynchus mykiss)
Actinopterygii Omy.12854 30
Fruit Fly
(Drosophila melanogaster)
Insecta CG11513 32
  • 33 (a)
CG6701 32
  • 33 (a)
CG6967 31 32
  • 27 (a)
ManyToMany
Baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes NAM7 31
  • 17 (a)
OneToMany
Thale Cress
(Arabidopsis thaliana)
eudicotyledons SDE3 30
  • 48.01 (n)
Rice
(Oryza sativa)
Liliopsida Os03g0160400 30
  • 49.24 (n)
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 53 (a)
OneToOne
Species where no ortholog for MOV10 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for MOV10 Gene

ENSEMBL:
Gene Tree for MOV10 (if available)
TreeFam:
Gene Tree for MOV10 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for MOV10: view image

Paralogs for MOV10 Gene

Paralogs for MOV10 Gene

(1) SIMAP similar genes for MOV10 Gene using alignment to 2 proteins:

  • MOV10_HUMAN
  • Q5JR04_HUMAN
genes like me logo Genes that share paralogs with MOV10: view

Variants for MOV10 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MOV10 Gene

SNP ID Clinical significance and condition Chr 01 pos Variation AA Info Type
711972 Benign: not provided 112,700,474(+) G/T SYNONYMOUS_VARIANT
713189 Benign: not provided 112,689,610(+) C/T SYNONYMOUS_VARIANT
731063 Benign: not provided 112,696,165(+) C/T SYNONYMOUS_VARIANT
731932 Likely Benign: not provided 112,690,036(+) G/A SYNONYMOUS_VARIANT
770115 Benign: not provided 112,695,579(+) T/C INTRON_VARIANT

Additional dbSNP identifiers (rs#s) for MOV10 Gene

Structural Variations from Database of Genomic Variants (DGV) for MOV10 Gene

Variant ID Type Subtype PubMed ID
esv27061 CNV gain+loss 19812545
esv3587217 CNV loss 21293372
esv997362 CNV deletion 20482838
nsv1133888 CNV deletion 24896259

Variation tolerance for MOV10 Gene

Residual Variation Intolerance Score: 7.96% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.63; 31.29% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for MOV10 Gene

Human Gene Mutation Database (HGMD)
MOV10
SNPedia medical, phenotypic, and genealogical associations of SNPs for
MOV10

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MOV10 Gene

Disorders for MOV10 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MOV10 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
autism spectrum disorder
  • asd
- elite association - COSMIC cancer census association via MalaCards
Search MOV10 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for MOV10

genes like me logo Genes that share disorders with MOV10: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MOV10 Gene

Publications for MOV10 Gene

  1. Uridylation by TUT4/7 Restricts Retrotransposition of Human LINE-1s. (PMID: 30122351) Warkocki Z … Dziembowski A (Cell 2018) 3 4
  2. IRAV (FLJ11286), an Interferon-Stimulated Gene with Antiviral Activity against Dengue Virus, Interacts with MOV10. (PMID: 27974568) Balinsky CA … Zoon KC (Journal of virology 2017) 3 4
  3. MOV10 Is a 5' to 3' RNA helicase contributing to UPF1 mRNA target degradation by translocation along 3' UTRs. (PMID: 24726324) Gregersen LH … Landthaler M (Molecular cell 2014) 3 4
  4. MOV10 and FMRP regulate AGO2 association with microRNA recognition elements. (PMID: 25464849) Kenny PJ … Ceman S (Cell reports 2014) 3 4
  5. The mammalian TRIM-NHL protein TRIM71/LIN-41 is a repressor of mRNA function. (PMID: 23125361) Loedige I … Filipowicz W (Nucleic acids research 2013) 3 4

Products for MOV10 Gene

  • Signalway ELISA kits for MOV10

Sources for MOV10 Gene