Aliases for MORN3 Gene

Aliases for MORN3 Gene

  • MORN Repeat Containing 3 2 3 5
  • MORN Repeat-Containing Protein 3 3 4
  • Membrane Occupation And Recognition Nexus Repeat Containing Protein 3

External Ids for MORN3 Gene

Previous GeneCards Identifiers for MORN3 Gene

  • GC12M120553
  • GC12M122089
  • GC12M119101

Summaries for MORN3 Gene

GeneCards Summary for MORN3 Gene

MORN3 (MORN Repeat Containing 3) is a Protein Coding gene. An important paralog of this gene is RSPH10B2.

Additional gene information for MORN3 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MORN3 Gene

Genomics for MORN3 Gene

GeneHancer (GH) Regulatory Elements for MORN3 Gene

Promoters and enhancers for MORN3 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MORN3 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MORN3 Gene

Genomic Locations for MORN3 Gene
chr12:121,648,742-121,672,639
(GRCh38/hg38)
Size:
23,898 bases
Orientation:
Minus strand
chr12:122,089,024-122,110,537
(GRCh37/hg19)
Size:
21,514 bases
Orientation:
Minus strand

Genomic View for MORN3 Gene

Genes around MORN3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MORN3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MORN3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MORN3 Gene

Proteins for MORN3 Gene

  • Protein details for MORN3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6PF18-MORN3_HUMAN
    Recommended name:
    MORN repeat-containing protein 3
    Protein Accession:
    Q6PF18
    Secondary Accessions:
    • Q86YQ9

    Protein attributes for MORN3 Gene

    Size:
    240 amino acids
    Molecular mass:
    27585 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for MORN3 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MORN3 Gene

Post-translational modifications for MORN3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MORN3 Gene

No data available for DME Specific Peptides for MORN3 Gene

Domains & Families for MORN3 Gene

Gene Families for MORN3 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for MORN3 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for MORN3 Gene

GenScript: Design optimal peptide antigens:
  • MORN repeat-containing protein 3 (MORN3_HUMAN)
genes like me logo Genes that share domains with MORN3: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MORN3 Gene

Function for MORN3 Gene

Phenotypes From GWAS Catalog for MORN3 Gene

Gene Ontology (GO) - Molecular Function for MORN3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with MORN3: view
genes like me logo Genes that share phenotypes with MORN3: view

Animal Model Products

CRISPR Products

miRNA for MORN3 Gene

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MORN3 Gene

Localization for MORN3 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MORN3 gene
Compartment Confidence
nucleus 2
extracellular 1
cytosol 1
mitochondrion 0

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for MORN3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus HDA 21630459
genes like me logo Genes that share ontologies with MORN3: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for MORN3 Gene

Pathways & Interactions for MORN3 Gene

PathCards logo

SuperPathways for MORN3 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MORN3 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MORN3 Gene

Drugs & Compounds for MORN3 Gene

No Compound Related Data Available

Transcripts for MORN3 Gene

mRNA/cDNA for MORN3 Gene

(2) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(23) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MORN3 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7
SP1: - -
SP2:

Relevant External Links for MORN3 Gene

GeneLoc Exon Structure for
MORN3
ECgene alternative splicing isoforms for
MORN3

Expression for MORN3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MORN3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for MORN3 Gene

This gene is overexpressed in Testis (x30.0).

NURSA nuclear receptor signaling pathways regulating expression of MORN3 Gene:

MORN3

SOURCE GeneReport for Unigene cluster for MORN3 Gene:

Hs.434154
genes like me logo Genes that share expression patterns with MORN3: view

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MORN3 Gene

Orthologs for MORN3 Gene

This gene was present in the common ancestor of animals.

Orthologs for MORN3 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MORN3 33 32
  • 98.89 (n)
OneToOne
cow
(Bos Taurus)
Mammalia MORN3 33 32
  • 88.75 (n)
OneToOne
dog
(Canis familiaris)
Mammalia MORN3 33 32
  • 86.53 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Morn3 17 33 32
  • 84.59 (n)
rat
(Rattus norvegicus)
Mammalia Morn3 32
  • 84.31 (n)
oppossum
(Monodelphis domestica)
Mammalia MORN3 33
  • 68 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia MORN3 33
  • 68 (a)
OneToOne
chicken
(Gallus gallus)
Aves MORN3 33 32
  • 62.87 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia MORN3 33
  • 55 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia morn3 32
  • 61.43 (n)
zebrafish
(Danio rerio)
Actinopterygii morn3 33 32
  • 59.52 (n)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG14490 33 32
  • 47.59 (n)
OneToMany
CG30429 33
  • 23 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 33
  • 54 (a)
OneToOne
Species where no ortholog for MORN3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MORN3 Gene

ENSEMBL:
Gene Tree for MORN3 (if available)
TreeFam:
Gene Tree for MORN3 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for MORN3: view image

Paralogs for MORN3 Gene

Paralogs for MORN3 Gene

(2) SIMAP similar genes for MORN3 Gene using alignment to 1 proteins:

  • MORN3_HUMAN
genes like me logo Genes that share paralogs with MORN3: view

Variants for MORN3 Gene

Sequence variations from dbSNP and Humsavar for MORN3 Gene

SNP ID Clin Chr 12 pos Variation AA Info Type
rs1000121670 -- 121,652,093(-) G/A intron_variant
rs1000124103 -- 121,670,041(-) T/C genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1000136023 -- 121,662,580(-) C/A/G/T intron_variant
rs1000178381 -- 121,665,747(-) A/C intron_variant
rs1000230726 -- 121,665,393(-) C/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for MORN3 Gene

Variant ID Type Subtype PubMed ID
esv3630952 CNV loss 21293372
nsv1053272 CNV gain 25217958
nsv1145633 CNV deletion 24896259
nsv560458 CNV loss 21841781

Variation tolerance for MORN3 Gene

Residual Variation Intolerance Score: 77.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.37; 27.03% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for MORN3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MORN3

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MORN3 Gene

Disorders for MORN3 Gene

Additional Disease Information for MORN3

No disorders were found for MORN3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MORN3 Gene

Publications for MORN3 Gene

  1. Characterization of membrane occupation and recognition nexus repeat containing 3, meiosis expressed gene 1 binding partner, in mouse male germ cells. (PMID: 25248657) Zhang L … Zhang ZB (Asian journal of andrology 2015) 2 3 56
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 56
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 56
  4. Pooled-matrix protein interaction screens using Barcode Fusion Genetics. (PMID: 27107012) Yachie N … Roth FP (Molecular systems biology 2016) 3 56
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 56

Products for MORN3 Gene

Sources for MORN3 Gene