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This gene encodes a protein that localizes to the nuclear matrix and forms nuclear bodies via an ATP-dependent mechanism. The protein is predicted to have coiled-coil and zinc finger domains and has RNA binding activity. Alternative splicing produces multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2016] See more...
Aliases for MORC3 Gene
Aliases for MORC3 Gene
External Ids for MORC3 Gene
- HGNC: 23572
- Entrez Gene: 23515
- Ensembl: ENSG00000159256
- OMIM: 610078
- UniProtKB: Q14149
Previous HGNC Symbols for MORC3 Gene
- ZCWCC3
Previous GeneCards Identifiers for MORC3 Gene
- GC21P036615
- GC21P037692
- GC21P023168
Summaries for MORC3 Gene
-
This gene encodes a protein that localizes to the nuclear matrix and forms nuclear bodies via an ATP-dependent mechanism. The protein is predicted to have coiled-coil and zinc finger domains and has RNA binding activity. Alternative splicing produces multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2016]
GeneCards Summary for MORC3 Gene
MORC3 (MORC Family CW-Type Zinc Finger 3) is a Protein Coding gene. Diseases associated with MORC3 include Adult Dermatomyositis and Childhood Type Dermatomyositis. Among its related pathways are Interactome of polycomb repressive complex 2 (PRC2). An important paralog of this gene is MORC4.
UniProtKB/Swiss-Prot Summary for MORC3 Gene
-
Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism (PubMed:20501696). Sumoylated MORC3-NBs can also associate with PML-NBs (PubMed:20501696). Recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity (PubMed:17332504). Binds RNA in vitro (PubMed:11927593). May be required for influenza A transcription during viral infection (PubMed:26202233).
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MORC3 Gene
Genomics for MORC3 Gene
GeneHancer (GH) Regulatory Elements for MORC3 Gene
Promoters and enhancers for MORC3 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around MORC3 on UCSC Golden Path with GeneCards custom track
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for MORC3
- Top Transcription factor binding sites by QIAGEN in the MORC3 gene promoter:
-
- E2F
- E2F-1
- E2F-2
- E2F-3a
- E2F-4
- E2F-5
- Egr-1
- NCX
- Nkx2-2
- p300
Genomic Locations for MORC3 Gene
Genomic Locations for MORC3 Gene
- chr21:36,320,189-36,386,148
- (GRCh38/hg38)
- Size:
- 65,960 bases
- Orientation:
- Plus strand
- chr21:37,692,487-37,758,446
- (GRCh37/hg19)
- Size:
- 65,960 bases
- Orientation:
- Plus strand
Genomic View for MORC3 Gene
Genes around MORC3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 21q22.12 by HGNC
- 21q22.12 by Entrez Gene
- 21q22.12 by Ensembl
MORC3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MORC3 Gene
Proteins for MORC3 Gene
-
Protein details for MORC3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q14149-MORC3_HUMAN
- Recommended name:
- MORC family CW-type zinc finger protein 3
- Protein Accession:
- Q14149
- A8KA92
- Q9UEZ2
Protein attributes for MORC3 Gene
- Size:
- 939 amino acids
- Molecular mass:
- 107113 Da
- Quaternary structure:
-
- Homodimer (PubMed:17332504). The sumoylated form interacts with PML (via SUMO-interacting motif) (PubMed:20501696, PubMed:17332504). Interacts with PT53 (PubMed:17332504). Interacts with influenza A virus PA and PB1 polymerase subunits during infection (PubMed:26202233).
- (Microbial infection) Interacts with influenza A virus PA and PB1 polymerase subunits during infection.
- SequenceCaution:
-
- Sequence=BAA09485.2; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAA89432.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for MORC3 Gene
Post-translational modifications for MORC3 Gene
- Sumoylation is involved in interaction with PML and localization to PML nuclear bodies.
-
Ubiquitination at Lys280, Lys293, Lys377, Lys404, Lys432, Lys710, Lys825, and Lys891
- NX_Q14149 (NX_Q14149-1)
- Modification sites at PhosphoSitePlus
Other Protein References for MORC3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Creative Diagnostics Anti-MORC3 monoclonal antibody, clone FQS21224(C)
- Creative Biolabs Recombinant Anti-Human MORC3 Antibody
- Novus Biologicals Antibodies for MORC3
-
Abcam antibodies for MORC3
- Invitrogen Antibodies for MORC3 (AFLGC-MORC3)
-
Santa Cruz Biotechnology (SCBT) Antibodies for MORC3
Protein Products
-
OriGene Purified Proteins for MORC3
- Search Origene for MassSpec and Protein Over-expression Lysates for MORC3
- Origene Custom Protein Services for MORC3
-
Signalway Proteins for MORC3
-
Abcam proteins for MORC3
No data available for DME Specific Peptides for MORC3 Gene
Domains & Families for MORC3 Gene
Gene Families for MORC3 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for MORC3 Gene
- Blocks:
-
- ATP-binding region, ATPase-like
- CW-type Zn-finger
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for MORC3 Gene
- GenScript: Design optimal peptide antigens:
-
- MORC3 protein (A2RU29_HUMAN)
- Zinc finger CW-type coiled-coil domain protein 3 (MORC3_HUMAN)
- MORC family CW-type zinc finger 3 (Q4VBZ9_HUMAN)
- MORC3 protein (Q86YD6_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MORC3 Gene
Function for MORC3 Gene
Molecular function for MORC3 Gene
- UniProtKB/Swiss-Prot Function:
- Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism (PubMed:20501696). Sumoylated MORC3-NBs can also associate with PML-NBs (PubMed:20501696). Recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity (PubMed:17332504). Binds RNA in vitro (PubMed:11927593). May be required for influenza A transcription during viral infection (PubMed:26202233).
Phenotypes From GWAS Catalog for MORC3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003723 | RNA binding | IEA | -- |
| GO:0008270 | zinc ion binding | IEA | -- |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for MORC3 Gene
- MGI mutant phenotypes for MORC3:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for MORC3:
-
- Synthetic lethal with imatinib mesylate
- Increased shRNA abundance (Z-score > 2)
- Increased G2M DNA content, increased 8N DNA content
- Decreased shRNA abundance
- Decreased shRNA abundance (Z-score < -2)
- Decreased viability
- no effect
- Increased vaccinia virus (VACV) infection
- Mildly decreased CFP-tsO45G cell surface transport
- Decreased NF-kappaB reporter expression
- Increased viability
- Increased transferrin (TF) endocytosis
Animal Models for MORC3 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for MORC3 - Select products 50% OFF >
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-
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- genomics-online: gRNA clones - Search results for available MORC3 gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for MORC3
miRNA for MORC3 Gene
- miRTarBase miRNAs that target MORC3
-
- hsa-mir-155-5p (MIRT020644)
- hsa-mir-101-3p (MIRT027287)
- hsa-mir-32-5p (MIRT028275)
- hsa-mir-21-5p (MIRT030797)
- hsa-mir-197-3p (MIRT048085)
- hsa-mir-30a-3p (MIRT085314)
- hsa-mir-30d-3p (MIRT085316)
- hsa-mir-218-2-3p (MIRT085317)
- hsa-mir-30e-3p (MIRT085318)
- hsa-mir-545-5p (MIRT085320)
- hsa-mir-584-5p (MIRT085321)
- hsa-mir-622 (MIRT085322)
- hsa-mir-758-5p (MIRT085323)
- hsa-mir-92a-3p (MIRT155523)
- hsa-mir-92b-3p (MIRT155532)
- hsa-mir-144-3p (MIRT556092)
- hsa-mir-5700 (MIRT556093)
- hsa-mir-153-3p (MIRT556094)
miRNA Products
Inhibitory RNA Products
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Clone Products
- Applied Biological Materials (abm): Clones for MORC3 - Select products 50% OFF >
- * MORC3 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for MORC3
- Addgene plasmids for MORC3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MORC3
- genomics-online: cdna clones - Search results for available MORC3 gene related products
- orf clones - Search results for available MORC3 gene related products
Cell Line Products
-
Horizon Cell Lines for MORC3
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for MORC3 Gene
Localization for MORC3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for MORC3 Gene
- Nucleus, nucleoplasm. Nucleus matrix. Nucleus, PML body. Note=Also found in PML-independent nuclear bodies. Localization to nuclear bodies is ATP-dependent. {ECO:0000269 PubMed:20501696}.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytoskeleton | 2 |
| mitochondrion | 2 |
| extracellular | 1 |
| cytosol | 1 |
- Nucleoplasm (4)
- Mitochondria (1)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005654 | nucleoplasm | IEA,IDA | -- |
| GO:0016363 | nuclear matrix | IEA | -- |
| GO:0016605 | PML body | IDA | 17332504 |
Pathways & Interactions for MORC3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Interactome of polycomb repressive complex 2 (PRC2) | ||
Pathways by source for MORC3 Gene
1 BioSystems pathway for MORC3 Gene
Interacting Proteins for MORC3 Gene
GPS-Prot Interaction Network for MORC3
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006468 | protein phosphorylation | IDA | 17332504 |
| GO:0007569 | cell aging | IDA | 17332504 |
| GO:0009791 | post-embryonic development | IEA | -- |
| GO:0016032 | viral process | IEA | -- |
| GO:0018105 | peptidyl-serine phosphorylation | IDA | 17332504 |
No data available for SIGNOR curated interactions for MORC3 Gene
Transcripts for MORC3 Gene
mRNA/cDNA for MORC3 Gene
- 3 REFSEQ mRNAs :
- 16 NCBI additional mRNA sequence :
- 12 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000400485 4224 bps (ENST00000400485.6)
- ENST00000484028 688 bps (ENST00000484028.1)
- ENST00000485299 687 bps (ENST00000485299.1)
- ENST00000485933 417 bps (ENST00000485933.1)
- ENST00000487909 4131 bps (ENST00000487909.5)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for MORC3 - Select products 50% OFF >
- * MORC3 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for MORC3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MORC3
- genomics-online: gRNA clones - Search results for available MORC3 gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for MORC3
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MORC3
- Browse OriGene Inhibitory RNA Products For MORC3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MORC3
- genomics-online: shRNA clones - Search results for available MORC3 gene related products
Clone Products
- Applied Biological Materials (abm): Clones for MORC3 - Select products 50% OFF >
- * MORC3 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for MORC3
- Addgene plasmids for MORC3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MORC3
- genomics-online: cdna clones - Search results for available MORC3 gene related products
- orf clones - Search results for available MORC3 gene related products
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12a | · | 12b | ^ | 13 | ^ | 14a | · | 14b | ^ | 15 | ^ | 16a | · | 16b | ^ | 17 | ^ | 18 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: |
Relevant External Links for MORC3 Gene
- GeneLoc Exon Structure for
- MORC3
Expression for MORC3 Gene
This gene is overexpressed in Peripheral blood mononuclear cells (15.9), Plasma (8.7), and Monocytes (7.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for MORC3 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MORC3
SOURCE GeneReport for Unigene cluster for MORC3 Gene:
Hs.421150mRNA Expression by UniProt/SwissProt for MORC3 Gene:
Q14149-MORC3_HUMAN
Tissue specificity:
Expressed in heart, placenta, skeletal muscle, brain, pancreas, lung, liver, but not kidney.
Evidence on tissue expression from TISSUES for MORC3 Gene
- Bone marrow(4.3)
- Muscle(2.6)
- Blood(2)
- Skin(2)
Primer Products
-
OriGene qPCR primer pairs for MORC3
-
OriGene qPCR primer pairs and template standards for MORC3
- genomics-online: primer clones - Search results for available MORC3 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for MORC3 Gene
Orthologs for MORC3 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | MORC3 31 30 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | MORC3 31 30 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | MORC3 31 30 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Morc3 17 31 30 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Morc3 30 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | MORC3 31 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | MORC3 31 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | MORC3 31 30 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | MORC3 31 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | morc3 30 |
|
||
| Str.11041 30 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.4065 30 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | morc3a 31 30 |
|
OneToMany | |
| morc3b 31 |
|
OneToMany | |||
| worm (Caenorhabditis elegans) |
Secernentea | morc-1 31 |
|
OneToMany |
- Species where no ortholog for MORC3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Evolution for MORC3 Gene
- ENSEMBL:
- Gene Tree for MORC3 (if available)
- TreeFam:
- Gene Tree for MORC3 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for MORC3: view image
Paralogs for MORC3 Gene
Variants for MORC3 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MORC3 Gene
| SNP ID | Clinical significance and condition | Chr 21 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 773090 | Benign: not provided | 36,369,252(+) | A/G | SYNONYMOUS_VARIANT |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2659831 | CNV | deletion | 23128226 |
| esv2671533 | CNV | deletion | 23128226 |
| esv33578 | CNV | loss | 17666407 |
| esv3646969 | CNV | loss | 21293372 |
| nsv3505 | CNV | deletion | 18451855 |
Residual Variation Intolerance Score:
11.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.37;
27.02% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for MORC3 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MORC3
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MORC3 Gene
Disorders for MORC3 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| adult dermatomyositis |
|
|
| childhood type dermatomyositis |
|
|
| influenza |
|
|
| interstitial lung disease |
|
|
| ecthyma |
|
|
Search MORC3 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for MORC3
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for MORC3 Gene
Publications for MORC3 Gene
- The Cellular Factor NXP2/MORC3 Is a Positive Regulator of Influenza Virus Multiplication. (PMID: 26202233) Ver LS … Ortín J (Journal of virology 2015) 3 4 54
- Two-step colocalization of MORC3 with PML nuclear bodies. (PMID: 20501696) Mimura Y … Inoue N (Journal of cell science 2010) 3 4 54
- Dynamic regulation of p53 subnuclear localization and senescence by MORC3. (PMID: 17332504) Takahashi K … Inoue N (Molecular biology of the cell 2007) 3 4 54
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 54
- The CW domain, a structural module shared amongst vertebrates, vertebrate-infecting parasites and higher plants. (PMID: 14607086) Perry J … Zhao Y (Trends in biochemical sciences 2003) 2 3 54
ExternalLinks
Products for MORC3 Gene
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- antibodies-online: Show 9 available MORC3 Antibodies ranked by validation data
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- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MORC3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MORC3
- Search GeneCopoeia for miRNA 3'UTR Target clone products for MORC3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MORC3
- Search for MORC3 ELISA kits at Signalway
- Signalway Proteins for MORC3
Sources for MORC3 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) H-invDB
- (47) HORDE
- (48) HUGE
- (49) IMGT
- (50) Leiden
- (51) miRBase
- (52) DME
- (53) OriGene
- (54) PubMed
- (55) R&D Systems
- (56) TGDB
- (57) Tocris
- (58) Abcam
- (59) Novus Biologicals
- (60) ProSpec
- (61) Sino Biological
- (62) GenScript
- (63) Qiagen
- (64) OCA
- (65) Proteopedia
- (66) MOPED
- (67) neXtProt
- (68) Reactome
- (69) GeneGo (Thomson Reuters)
- (70) DISEASES
- (71) SIMAP
- (72) GenomeRNAi
- (73) LifeMap
- (74) miRTarBase
- (75) MalaCards
- (76) Invitrogen
- (77) BitterDB
- (78) ESI-BIO
- (79) RefSeq
- (80) BioSystems
- (81) MaxQB
- (82) IUPHAR
- (83) BioGPS
- (84) Illumina
- (85) COMPARTMENTS
- (86) HOMER
- (87) PaxDb
- (88) ApexBio
- (89) Addgene
- (90) antibodies-online
- (91) CYP
- (92) NONCODE
- (93) TreeFam
- (94) PathCards
- (95) GeneReviews
- (96) GeneTex
- (97) Taconic Biosciences
- (98) GTEx
- (99) ProteomicsDB
- (100) SCBT
- (101) DGIdb
- (102) ClinicalTrials
- (103) RVIS
- (104) SIGNOR
- (105) diseasecard
- (106) NIH Rare Diseases
- (107) Orphanet
- (108) UMLS
- (109) GTR
- (110) Disease Ontology
- (111) Genetics Home Reference
- (112) MeSH
- (113) MedlinePlus
- (114) CDC
- (115) NINDS
- (116) NCBI Bookshelf
- (117) ClinVar
- (118) Gene Damage Index
- (119) HPO
- (120) UDN
- (121) VISTA
- (122) FANTOM5
- (123) ENCODE
- (124) ProSci
- (125) Horizon
- (126) The Signaling Pathways Project (SPP)
- (127) IID
- (128) VectorBuilder
- (129) SNPedia
- (130) BRCA Exchange
- (131) CIViC
- (132) ProteoGenix
- (133) dbSUPER
- (134) TISSUES
- (135) Gene ORGANizer
- (136) abm
- (137) Human Protein Atlas
- (138) GWAS Catalog
- (139) Monarch Initiative
- (140) DataMed
- (141) HumanCyc
- (142) genomics-online
- (143) UCNEbase
- (144) EPDnew
- (145) Applied Biosystems
- (146) GlyConnect
- (147) Aminode
- (148) GeneCopoeia
- (149) GPS-Prot
- (150) RNACentral
- (151) LncRNADisease
- (152) LOVD
- (153) miR2Disease
- (154) DiseaseEnhancer
- (155) Boster Bio
- (156) Biorbyt
- (157) Biocompare
- (158) Mastermind
- (159) CTD^2 Dashboard
- (160) CraniofacialAtlas
- (161) GeneImprint
- (162) Synthego
- (163) Bio Basic
- (164) ENA
- (165) GtRNAdb
- (166) LncBase
- (167) LncBook
- (168) LNCipedia
- (169) LncRNAdb
- (170) Modomics
- (171) PDBe
- (172) Rfam
- (173) SILVA
- (174) snOPY
- (175) SRPDB
- (176) GENCODE
- (177) TarBase
- (178) MyBioSource
- (179) Signalway Antibody