Aliases for MOGAT1 Gene
External Ids for MOGAT1 Gene
Previous HGNC Symbols for MOGAT1 Gene
Previous GeneCards Identifiers for MOGAT1 Gene
Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 22.214.171.124) catalyzes the synthesis of diacylglycerols, the precursor of physiologically important lipids such as triacylglycerol and phospholipids (Yen et al., 2002 [PubMed 12077311]).[supplied by OMIM, Mar 2008]
GeneCards Summary for MOGAT1 Gene
MOGAT1 (Monoacylglycerol O-Acyltransferase 1) is a Protein Coding gene. Among its related pathways are triacylglycerol biosynthesis and Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha). Gene Ontology (GO) annotations related to this gene include transferase activity, transferring acyl groups other than amino-acyl groups and diacylglycerol O-acyltransferase activity. An important paralog of this gene is MOGAT2.
UniProtKB/Swiss-Prot for MOGAT1 Gene
Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Probably not involved in absorption of dietary fat in the small intestine (By similarity).