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This gene encodes a nuclear protein, which contains a homeobox domain and is a transcription factor. Mutations in this gene result in Currarino syndrome, an autosomic dominant congenital malformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] See more...
Aliases for MNX1 Gene
Aliases for MNX1 Gene
External Ids for MNX1 Gene
- HGNC: 4979
- NCBI Entrez Gene: 3110
- Ensembl: ENSG00000130675
- OMIM®: 142994
- UniProtKB/Swiss-Prot: P50219
Previous HGNC Symbols for MNX1 Gene
- HLXB9
Previous GeneCards Identifiers for MNX1 Gene
- GC07M156491
- GC07M156786
- GC07M150530
Summaries for MNX1 Gene
-
This gene encodes a nuclear protein, which contains a homeobox domain and is a transcription factor. Mutations in this gene result in Currarino syndrome, an autosomic dominant congenital malformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
GeneCards Summary for MNX1 Gene
MNX1 (Motor Neuron And Pancreas Homeobox 1) is a Protein Coding gene. Diseases associated with MNX1 include Currarino Syndrome and Meningocele. Among its related pathways are Neural Stem Cell Differentiation Pathways and Lineage-specific Markers and Regulation of beta-cell development. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and sequence-specific DNA binding.
UniProtKB/Swiss-Prot Summary for MNX1 Gene
-
Putative transcription factor involved in pancreas development and function.
Additional gene information for MNX1 Gene
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MNX1 Gene
Genomics for MNX1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for MNX1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around MNX1 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for MNX1
- Top Transcription factor binding sites by QIAGEN in the MNX1 gene promoter:
-
- AML1a
- FOXF2
- GATA-1
- GATA-3
- Nkx2-5
- POU2F1
- POU2F1a
- STAT3
Genomic Locations for MNX1 Gene
Latest Assembly
- chr7:156,994,051-157,010,663
- (GRCh38/hg38)
- Size:
- 16,613 bases
- Orientation:
- Minus strand
Previous Assembly
- chr7:156,797,548-156,803,357
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 5,810 bases
- Orientation:
- Minus strand
Genomic View for MNX1 Gene
Genes around MNX1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 7q36.3 by HGNC
- 7q36.3 by Entrez Gene
- 7q36.3 by Ensembl
MNX1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MNX1 Gene
Proteins for MNX1 Gene
-
Protein details for MNX1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P50219-MNX1_HUMAN
- Recommended name:
- Motor neuron and pancreas homeobox protein 1
- Protein Accession:
- P50219
- F5H401
- Q9Y648
Protein attributes for MNX1 Gene
- Size:
- 401 amino acids
- Molecular mass:
- 40569 Da
- Quaternary structure:
- No Data Available
Protein Expression for MNX1 Gene
Post-translational modifications for MNX1 Gene
Other Protein References for MNX1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- G Biosciences Immunotag™ MNX1 Polyclonal Antibody and Immunotag™ MNX1 Antibody
-
Custom Antibody ServicesOriGene Antibodies for MNX1
- Novus Biologicals Antibodies for MNX1
-
Abcam antibodies for MNX1
- Invitrogen Antibodies for MNX1 (AFLGC-MNX1)
-
Biorbyt antibodies for MNX1
-
Santa Cruz Biotechnology (SCBT) Antibodies for MNX1
- Sino Biological Antibodies for MNX1
Protein products for research
- Search Origene for MassSpec and Protein Over-expression Lysates for MNX1
- Origene Custom Protein Services for MNX1
- antibodies-online: Show 3 available MNX1 Proteins ranked by validation data
- Compare Top MNX1 Proteins
-
Quality Products:
Assay products for research
- antibodies-online: Show 7 available MNX1 Elisa Kits ranked by validation data
- Compare Top MNX1 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for MNX1 Gene
Domains & Families for MNX1 Gene
Gene Families for MNX1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Disease related genes
- Plasma proteins
- Predicted intracellular proteins
- Transcription factors
Protein Domains for MNX1 Gene
Suggested Antigen Peptide Sequences for MNX1 Gene
- GenScript: Design optimal peptide antigens:
-
- Homeobox protein HB9 (MNX1_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MNX1 Gene
Function for MNX1 Gene
Molecular function for MNX1 Gene
- UniProtKB/Swiss-Prot Function:
- Putative transcription factor involved in pancreas development and function.
Phenotypes From GWAS Catalog for MNX1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | ISA | -- |
| GO:0003677 | DNA binding | IEA | -- |
| GO:1990837 | sequence-specific double-stranded DNA binding | IBA,IDA | 28473536 |
Phenotypes for MNX1 Gene
- MGI mutant phenotypes for MNX1:
-
inferred from 6 alleles
- normal phenotype
- nervous system phenotype
- muscle phenotype
- homeostasis/metabolism phenotype
- growth/size/body region phenotype
- cellular phenotype
- cardiovascular system phenotype
- behavior/neurological phenotype
- immune system phenotype
- respiratory system phenotype
- mortality/aging
- hematopoietic system phenotype
- digestive/alimentary phenotype
- endocrine/exocrine gland phenotype
- skeleton phenotype
- adipose tissue phenotype
- GenomeRNAi human phenotypes for MNX1:
Animal Models for MNX1 Gene
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for MNX1 - Starting at $85 >
- * MNX1 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for MNX1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MNX1
-
Santa Cruz Biotechnology (SCBT) CRISPR for MNX1
miRNA for MNX1 Gene
- miRTarBase miRNAs that target MNX1
-
- hsa-miR-101-3p (MIRT027276)
- hsa-miR-8055 (MIRT506559)
- hsa-miR-3180-5p (MIRT506560)
- hsa-miR-887-3p (MIRT506561)
- hsa-miR-6720-5p (MIRT506562)
- hsa-miR-6512-3p (MIRT506563)
- hsa-miR-582-5p (MIRT506564)
- hsa-miR-2052 (MIRT506565)
- hsa-miR-5186 (MIRT506566)
- hsa-miR-4645-3p (MIRT506567)
- hsa-miR-4530 (MIRT506568)
- hsa-miR-4328 (MIRT506569)
- hsa-miR-7161-5p (MIRT506570)
- hsa-miR-548u (MIRT506571)
- hsa-miR-338-3p (MIRT506572)
- hsa-miR-200a-3p (MIRT735389)
- mmu-miR-141-3p (MIRT735390)
- mmu-miR-200a-3p (MIRT735391)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MNX1
- Browse OriGene Inhibitory RNA Products For MNX1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MNX1
Clone products for research
- Applied Biological Materials (abm): Clones for MNX1 - Starting at $45 >
- * MNX1 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for MNX1
- Addgene plasmids for MNX1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MNX1
Cell Lines for research
-
Horizon Cell Lines for MNX1
No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for MNX1 Gene
Localization for MNX1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for MNX1 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 4 |
| extracellular | 2 |
| cytoskeleton | 2 |
| plasma membrane | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
- Cytosol (2)
- Nucleoli (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000785 | chromatin | ISA | -- |
| GO:0005634 | nucleus | IBA | 21873635 |
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0005730 | nucleolus | IDA | -- |
| GO:0005829 | cytosol | IDA | -- |
Pathways & Interactions for MNX1 Gene
Pathways by source for MNX1 Gene
1 KEGG pathway for MNX1 Gene
1 R&D Systems pathway for MNX1 Gene
Interacting Proteins for MNX1 Gene
GPS-Prot Interaction Network for MNX1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0006357 | regulation of transcription by RNA polymerase II | IEA | -- |
| GO:0007417 | central nervous system development | IBA | 21873635 |
| GO:0021520 | spinal cord motor neuron cell fate specification | IBA | 21873635 |
| GO:0031018 | endocrine pancreas development | IBA | 21873635 |
Transcripts for MNX1 Gene
mRNA/cDNA for MNX1 Gene
- 2 REFSEQ mRNAs :
- 9 NCBI additional mRNA sequence :
- 8 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000252971 2185 nts (view in UCSC)
- ENST00000425745 322 nts (view in UCSC)
- ENST00000428439 631 nts (view in UCSC)
- ENST00000469500 209 nts (view in UCSC)
- ENST00000474448 1101 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for MNX1 - Starting at $85 >
- * MNX1 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for MNX1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MNX1
-
Santa Cruz Biotechnology (SCBT) CRISPR for MNX1
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MNX1
- Browse OriGene Inhibitory RNA Products For MNX1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MNX1
Clone products for research
- Applied Biological Materials (abm): Clones for MNX1 - Starting at $45 >
- * MNX1 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for MNX1
- Addgene plasmids for MNX1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MNX1
Relevant External Links for MNX1 Gene
- GeneLoc Exon Structure for
- MNX1
Expression for MNX1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Spinal Cord (Nervous System)
- Motor Neural Progenitor Cells Motor Neural Progenitor Domain
- Motor Neurons Motor Neural Progenitor Domain
- Motor neuron-like cells(Hester ME et. al. 2011)
- Precursor lateral motor column neuron EBs(Amoroso MW et. al. 2013)
- Motor neuron progenitors(Di Giorgio FP et. al. 2008)
-
Neurons
- Motor Neural Progenitor Cells Motor Neural Progenitor Domain
- Motor Neurons Motor Neural Progenitor Domain
- Motor neuron-like cells(Hester ME et. al. 2011)
- Precursor lateral motor column neuron EBs(Amoroso MW et. al. 2013)
- Motor neuron-like cells(Corti S et. al. 2009)
- Motor Neurons (Nervous System)
-
Pancreas (Endocrine System)
- Immature Beta Progenitor Cells Dorsal Pancreatic Bud
- Endocrine Progenitor Cells Dorsal Pancreatic Bud
- Bipotent Endocrine/Duct Progenitor Cells Dorsal Pancreatic Bud
- Beta/Delta Progenitor Cells Dorsal Pancreatic Bud
- Pancreatic Progenitor Cells Ventral Pancreatic Bud
-
Epithelial Cells
- Endocrine Progenitor Cells Dorsal Pancreatic Bud
- Bipotent Endocrine/Duct Progenitor Cells Dorsal Pancreatic Bud
- Pancreatic Progenitor Cells Ventral Pancreatic Bud
- Endocrine Progenitor Cells Ventral Pancreatic Bud
- Prepancreatic Foregut Endoderm Cells Prepancreatic Dorsal Foregut Endoderm
- Brain (Nervous System)
- NULL (Uncategorized)
-
Neural Tube (Nervous System)
- Motor Neural Progenitor Cells Motor Neural Progenitor Domain
- Motor Neurons Motor Neural Progenitor Domain
- Neuronal progenitor cells(Wichterle H et. al. 2002)
-
Gut Tube (Gastrointestinal Tract)
- Prepancreatic Foregut Endoderm Cells Prepancreatic Dorsal Foregut Endoderm
- Dorsal Foregut Endoderm Cells Dorsal Foregut Endoderm
- Ventral Foregut Endoderm Cells Ventral Foregut Endoderm
-
Limb (Muscoskeletal System)
- Zone Of Polarizing Activity Cells Limb Bud
-
Mesoderm (Gastrulation Derivatives)
- Zone Of Polarizing Activity Cells Limb Bud
- Neural Crest (Gastrulation Derivatives)
mRNA differential expression in normal tissues according to GTEx for MNX1 Gene
This gene is overexpressed in Pancreas (x24.8), Colon - Transverse (x6.1), and Small Intestine - Terminal Ileum (x4.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for MNX1 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MNX1
SOURCE GeneReport for Unigene cluster for MNX1 Gene:
Hs.37035mRNA Expression by UniProt/SwissProt for MNX1 Gene:
P50219-MNX1_HUMAN
Tissue specificity:
Expressed in lymphoid and pancreatic tissues.
Evidence on tissue expression from TISSUES for MNX1 Gene
- Pancreas(2.3)
Phenotype-based relationships between genes and organs from Gene ORGANizer for MNX1 Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- digestive
- endocrine
- immune
- integumentary
- nervous
- reproductive
- skeletal muscle
- skeleton
- urinary
Regions:
Head and neck:
- brain
- head
- meninges
- neck
Thorax:
- esophagus
Abdomen:
- intestine
- kidney
- large intestine
- small intestine
- stomach
Pelvis:
- anus
- pelvis
- prostate
- rectum
- ureter
- urethra
- urinary bladder
- uterus
- vagina
General:
- blood
- peripheral nerve
- peripheral nervous system
- skin
- spinal column
- spinal cord
- vertebrae
- white blood cell
Primer products for research
-
OriGene qPCR primer pairs for MNX1
-
OriGene qPCR primer pairs and template standards for MNX1
Gene Expression Assays for research
No data available for Protein differential expression in normal tissues and Protein tissue co-expression partners for MNX1 Gene
Orthologs for MNX1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | MNX1 29 30 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | MNX1 29 30 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | MNX1 29 30 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Mnx1 29 16 30 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Mnx1 29 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | MNX1 30 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | MNX1 30 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | MNX1 29 30 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | MNX1 30 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | mnx1 29 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | hlxb9-A 29 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | mnx1 29 30 |
|
OneToOne | |
| Fruit Fly (Drosophila melanogaster) |
Insecta | exex 30 |
|
OneToOne | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 30 |
|
OneToOne |
- Species where no ortholog for MNX1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for MNX1 Gene
- ENSEMBL:
- Gene Tree for MNX1 (if available)
- TreeFam:
- Gene Tree for MNX1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for MNX1: view image
- Alliance of Genome Resources:
- Additional Orthologs for MNX1
Paralogs for MNX1 Gene
(29) SIMAP similar genes for MNX1 Gene using alignment to 6 proteins:
- MNX1_HUMAN
- C9JFT4_HUMAN
- C9K088_HUMAN
- S4R364_HUMAN
- S4R3G1_HUMAN
- S4R464_HUMAN
No data available for Paralogs for MNX1 Gene
Variants for MNX1 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MNX1 Gene
| SNP ID | Clinical significance and condition | Chr 07 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 1047679 | Uncertain Significance: not provided | 157,009,842(-) |
G/C NM_005515.4(MNX1):c.509C>G (p.Ala170Gly) |
MISSENSE | |
| rs1064794653 | Conflicting Interpretations: Inborn genetic diseases; not provided | 157,005,841(-) |
T/G NM_005515.4(MNX1):c.885A>C (p.Lys295Asn) |
MISSENSE | |
| rs1064796665 | Likely Pathogenic: not provided | 157,006,519(-) |
CG/C NM_005515.4(MNX1):c.811del (p.Arg271fs) |
FRAMESHIFT | |
| rs121912546 | Pathogenic: Currarino triad | 157,006,556(-) |
G/A NM_005515.4(MNX1):c.775C>T (p.Gln259Ter) |
NONSENSE | |
| rs121912547 | Pathogenic: Currarino triad | 157,009,859(-) |
G/T NM_005515.4(MNX1):c.492C>A (p.Tyr164Ter) |
NONSENSE |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
Gene Damage Index Score:
0.65;
13.80% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for MNX1 Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MNX1 Gene
Disorders for MNX1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| currarino syndrome |
|
|
| meningocele |
|
|
| teratoma |
|
|
| oeis complex |
|
|
| bladder exstrophy |
|
|
Search MNX1 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
MNX1_HUMAN- Currarino syndrome (CURRAS) [MIM:176450]: The triad of a presacral tumor, sacral agenesis and anorectal malformation constitutes the Currarino syndrome which is caused by dorsal-ventral patterning defects during embryonic development. The syndrome occurs in the majority of patients as an autosomal dominant trait. {ECO:0000269 PubMed:10631160, ECO:0000269 PubMed:10749657, ECO:0000269 PubMed:19853743, ECO:0000269 PubMed:22820079}. Note=The disease is caused by variants affecting the gene represented in this entry.
Additional Disease Information for MNX1
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for Genatlas for MNX1 Gene
Publications for MNX1 Gene
- A homeobox gene, HLXB9, is the major locus for dominantly inherited sacral agenesis. (PMID: 9843207) Ross AJ … Strachan T (Nature genetics 1998) 2 3 22 72
- Novel mutations in the MNX1 gene in two families with Currarino syndrome and variable phenotype. (PMID: 22820079) Markljung E … Nordenskjöld A (Gene 2012) 3 4 72
- MNX1 (HLXB9) mutations in Currarino patients. (PMID: 19853743) Garcia-Barceló MM … Tam PK (Journal of pediatric surgery 2009) 3 4 22
- Mutation analysis and embryonic expression of the HLXB9 Currarino syndrome gene. (PMID: 10749657) Hagan DM … Homfray T (American journal of human genetics 2000) 3 4 22
- A novel human homeobox gene distantly related to proboscipedia is expressed in lymphoid and pancreatic tissues. (PMID: 7914194) Harrison KA … Kehrl JH (The Journal of biological chemistry 1994) 3 4 22
ExternalLinks
Products for MNX1 Gene
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- antibodies-online: Show 16 available MNX1 Antibodies ranked by validation data
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- Quality Products:
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- Santa Cruz Biotechnology (SCBT) Antibodies for MNX1
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- Santa Cruz Biotechnology (SCBT) CRISPR for MNX1
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- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MNX1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MNX1
- Search GeneCopoeia for miRNA 3'UTR Target clone products for MNX1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MNX1
- Biorbyt antibodies for MNX1
Sources for MNX1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Apr-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) ASD
- (27) SAGE
- (28) SOURCE
- (29) HomoloGene
- (30) PanEnsembl
- (31) euGenes
- (32) SGD
- (33) FlyBase
- (34) WormBase
- (35) Pseudogene
- (36) DGV
- (37) dbSNP
- (38) GenAtlas
- (39) HGMD
- (40) GAD
- (41) BGMUT
- (42) HuGE
- (43) Atlas
- (44) GenBank
- (45) HORDE
- (46) HUGE
- (47) IMGT
- (48) Leiden
- (49) miRBase
- (50) DME
- (51) OriGene
- (52) PubMed
- (53) R&D Systems
- (54) Tocris
- (55) Abcam
- (56) Novus Biologicals
- (57) ProSpec
- (58) Sino Biological
- (59) GenScript
- (60) Qiagen
- (61) OCA
- (62) Proteopedia
- (63) MOPED
- (64) neXtProt
- (65) Reactome
- (66) GeneGo (Thomson Reuters)
- (67) DISEASES
- (68) SIMAP
- (69) GenomeRNAi
- (70) LifeMap
- (71) miRTarBase
- (72) MalaCards
- (73) Invitrogen
- (74) BitterDB
- (75) ESI-BIO
- (76) RefSeq
- (77) BioSystems
- (78) MaxQB
- (79) IUPHAR
- (80) BioGPS
- (81) Illumina
- (82) COMPARTMENTS
- (83) HOMER
- (84) PaxDb
- (85) ApexBio
- (86) Addgene
- (87) antibodies-online
- (88) CYP
- (89) NONCODE
- (90) TreeFam
- (91) PathCards
- (92) GeneReviews
- (93) GeneTex
- (94) Taconic Biosciences
- (95) GTEx
- (96) ProteomicsDB
- (97) SCBT
- (98) DGIdb
- (99) ClinicalTrials
- (100) RVIS
- (101) SIGNOR
- (102) diseasecard
- (103) NIH Rare Diseases
- (104) Orphanet
- (105) UMLS
- (106) GTR
- (107) Disease Ontology
- (108) MedlinePlus Genetics
- (109) MeSH
- (110) MedlinePlus
- (111) CDC
- (112) NINDS
- (113) NCBI Bookshelf
- (114) ClinVar
- (115) Gene Damage Index
- (116) HPO
- (117) UDN
- (118) VISTA
- (119) FANTOM5
- (120) ENCODE
- (121) ProSci
- (122) Horizon
- (123) The Signaling Pathways Project (SPP)
- (124) IID
- (125) VectorBuilder
- (126) SNPedia
- (127) BRCA Exchange
- (128) CIViC
- (129) ProteoGenix
- (130) dbSUPER
- (131) TISSUES
- (132) Gene ORGANizer
- (133) abm
- (134) Human Protein Atlas
- (135) GWAS Catalog
- (136) Monarch Initiative
- (137) DataMed
- (138) HumanCyc
- (139) UCNEbase
- (140) EPDnew
- (141) Applied Biosystems
- (142) GlyConnect
- (143) Aminode
- (144) GeneCopoeia
- (145) GPS-Prot
- (146) RNAcentral
- (147) LncRNADisease
- (148) LOVD
- (149) miR2Disease
- (150) DiseaseEnhancer
- (151) Boster Bio
- (152) Biorbyt
- (153) Biocompare
- (154) Mastermind
- (155) CTD^2 Dashboard
- (156) CraniofacialAtlas
- (157) GeneImprint
- (158) Synthego
- (159) ENA
- (160) GtRNAdb
- (161) LncBase
- (162) LncBook
- (163) LNCipedia
- (164) Modomics
- (165) PDBe
- (166) Rfam
- (167) SILVA
- (168) snOPY
- (169) SRPDB
- (170) GENCODE
- (171) TarBase
- (172) Open Targets Platform
- (173) 5SRRNADB
- (174) snoDB
- (175) MirGeneDB
- (176) Alliance of Genome Resources