Aliases for MNX1 Gene
External Ids for MNX1 Gene
Previous HGNC Symbols for MNX1 Gene
Previous GeneCards Identifiers for MNX1 Gene
This gene encodes a nuclear protein, which contains a homeobox domain and is a transcription factor. Mutations in this gene result in Currarino syndrome, an autosomic dominant congenital malformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
GeneCards Summary for MNX1 Gene
MNX1 (Motor Neuron And Pancreas Homeobox 1) is a Protein Coding gene. Diseases associated with MNX1 include Currarino Syndrome and Anorectal Anomalies. Among its related pathways are Regulation of beta-cell development and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and sequence-specific DNA binding. An important paralog of this gene is GBX1.
UniProtKB/Swiss-Prot for MNX1 Gene
Putative transcription factor involved in pancreas development and function.