Aliases for MMP28 Gene
External Ids for MMP28 Gene
Previous GeneCards Identifiers for MMP28 Gene
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, such as asthma and metastasis. This gene encodes a secreted enzyme that degrades casein. Its expression pattern suggests that it plays a role in tissue homeostasis and in wound repair. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]
GeneCards Summary for MMP28 Gene
MMP28 (Matrix Metallopeptidase 28) is a Protein Coding gene. Among its related pathways are Integrin Pathway and GPCR Pathway. Gene Ontology (GO) annotations related to this gene include calcium ion binding and metallopeptidase activity. An important paralog of this gene is MMP15.
UniProtKB/Swiss-Prot Summary for MMP28 Gene
Can degrade casein. Could play a role in tissues homeostasis and repair.
Matrix metalloproteases (matrix metalloproteinase, MMPs), also called matrixins, are zinc-dependent endopeptidases and the major proteases in ECM degradation. MMPs are capable of degrading several extracellular molecules and a number of bioactive molecules.