External Ids for MLN Gene
Previous GeneCards Identifiers for MLN Gene
This gene encodes a small peptide hormone that is secreted by cells of the small intestine to regulate gastrointestinal contractions and motility. Proteolytic processing of the secreted protein produces the mature peptide and a byproduct referred to as motilin-associated peptide (MAP). Three transcript variants encoding different preproprotein isoforms but the same mature peptide have been found for this gene. [provided by RefSeq, May 2010]
GeneCards Summary for MLN Gene
MLN (Motilin) is a Protein Coding gene. Diseases associated with MLN include Gastroparesis and Paralytic Ileus. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include signaling receptor binding and hormone activity.
UniProtKB/Swiss-Prot Summary for MLN Gene
Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle.