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MLLT6 (MLLT6, PHD Finger Containing) is a Protein Coding gene. Diseases associated with MLLT6 include Pineal Region Germinoma and Liddle Syndrome 1. An important paralog of this gene is MLLT10.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IPI | 16713569 |
GO:0031491 | nucleosome binding | IDA | 26439302 |
GO:0042393 | histone binding | IPI | 26439302 |
GO:0046872 | metal ion binding | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003014 | renal system process | IEA | -- |
GO:0006355 | regulation of transcription, DNA-templated | TAS | 8058765 |
GO:0007588 | excretion | IEA | -- |
GO:0010765 | positive regulation of sodium ion transport | IEA | -- |
GO:0035811 | negative regulation of urine volume | IEA | -- |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | MLLT6 30 |
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Dog (Canis familiaris) |
Mammalia | MLLT6 30 |
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Cow (Bos Taurus) |
Mammalia | MLLT6 30 |
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Mouse (Mus musculus) |
Mammalia | Mllt6 30 17 |
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Rat (Rattus norvegicus) |
Mammalia | Mllt6 30 |
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Chicken (Gallus gallus) |
Aves | MLLT6 30 |
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Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | mllt6 30 |
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Worm (Caenorhabditis elegans) |
Secernentea | zfp-1 32 |
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SNP ID | Clinical significance and condition | Chr 17 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
787451 | Benign: not provided | 38,711,996(+) | C/T | SYNONYMOUS_VARIANT | |
791346 | Benign: not provided | 38,707,806(+) | A/G | SYNONYMOUS_VARIANT | |
rs17855918 | - | p.Ala33Val | |||
rs2241012 | - | p.Ala198Thr |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv21810 | CNV | gain | 19812545 |
nsv1071381 | CNV | deletion | 25765185 |
nsv1126456 | CNV | deletion | 24896259 |
nsv1146669 | OTHER | inversion | 26484159 |
nsv470585 | CNV | loss | 18288195 |
nsv833438 | CNV | loss | 17160897 |
nsv953894 | CNV | deletion | 24416366 |
Disorder | Aliases | PubMed IDs |
---|---|---|
pineal region germinoma |
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liddle syndrome 1 |
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