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This gene encodes the carbohydrate-binding protein malectin which is a Type I membrane-anchored endoplasmic reticulum protein. This protein has an affinity for Glc2Man9GlcNAc2 (G2M9) N-glycans and is involved in regulating glycosylation in the endoplasmic reticulum. This protein has also been shown to interact with ribophorin I and may be involved in the directing the degradati... See more...
Aliases for MLEC Gene
Aliases for MLEC Gene
External Ids for MLEC Gene
- HGNC: 28973
- Entrez Gene: 9761
- Ensembl: ENSG00000110917
- OMIM: 613802
- UniProtKB: Q14165
Previous HGNC Symbols for MLEC Gene
- KIAA0152
Previous GeneCards Identifiers for MLEC Gene
- GC12P119611
- GC12P121124
- GC12P118134
Summaries for MLEC Gene
-
This gene encodes the carbohydrate-binding protein malectin which is a Type I membrane-anchored endoplasmic reticulum protein. This protein has an affinity for Glc2Man9GlcNAc2 (G2M9) N-glycans and is involved in regulating glycosylation in the endoplasmic reticulum. This protein has also been shown to interact with ribophorin I and may be involved in the directing the degradation of misfolded proteins. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
GeneCards Summary for MLEC Gene
MLEC (Malectin) is a Protein Coding gene. Among its related pathways are Calnexin/calreticulin cycle and Transport to the Golgi and subsequent modification. Gene Ontology (GO) annotations related to this gene include enzyme binding and carbohydrate binding.
UniProtKB/Swiss-Prot Summary for MLEC Gene
-
Carbohydrate-binding protein with a strong ligand preference for Glc2-N-glycan. May play a role in the early steps of protein N-glycosylation (By similarity).
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MLEC Gene
Genomics for MLEC Gene
GeneHancer (GH) Regulatory Elements for MLEC Gene
Promoters and enhancers for MLEC Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around MLEC on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the MLEC gene promoter:
-
- Brachyury
- CBF-C
- CP1A
- CP1C
- Elk-1
- GATA-3
- LCR-F1
- NF-Y
- Pax-4a
- XBP-1
Genomic Locations for MLEC Gene
Genomic Locations for MLEC Gene
- chr12:120,687,124-120,701,864
- (GRCh38/hg38)
- Size:
- 14,741 bases
- Orientation:
- Plus strand
- chr12:121,124,672-121,139,667
- (GRCh37/hg19)
- Size:
- 14,996 bases
- Orientation:
- Plus strand
Genomic View for MLEC Gene
Genes around MLEC on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12q24.31 by HGNC
- 12q24.31 by Entrez Gene
- 12q24.31 by Ensembl
MLEC Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MLEC Gene
Proteins for MLEC Gene
-
Protein details for MLEC Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q14165-MLEC_HUMAN
- Recommended name:
- Malectin
- Protein Accession:
- Q14165
Protein attributes for MLEC Gene
- Size:
- 292 amino acids
- Molecular mass:
- 32234 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAA09773.2; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for MLEC Gene
Post-translational modifications for MLEC Gene
Other Protein References for MLEC Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Creative Diagnostics Anti-MLEC (internal region) polyclonal antibody
- Novus Biologicals Antibodies for MLEC
-
Abcam antibodies for MLEC
- Invitrogen Antibodies for MLEC (AFLGC-MLEC)
Protein Products
- Creative Biomart Recombinant Human MLEC, His-tagged and Recombinant Human MLEC Protein, MYC/DDK-tagged
-
OriGene Purified Proteins for MLEC
- Search Origene for MassSpec and Protein Over-expression Lysates for MLEC
- Origene Custom Protein Services for MLEC
- ProSpec Recombinant Proteins for MLEC
- antibodies-online: Show 9 available MLEC Proteins ranked by validation data
- Compare Top MLEC Proteins
-
Quality Products:
-
Abcam proteins for MLEC
No data available for DME Specific Peptides for MLEC Gene
Domains & Families for MLEC Gene
Gene Families for MLEC Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
- Predicted membrane proteins
- Predicted secreted proteins
Protein Domains for MLEC Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for MLEC Gene
- GenScript: Design optimal peptide antigens:
-
- Malectin (MLEC_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q14165- Family:
-
- Belongs to the malectin family.
Function for MLEC Gene
Molecular function for MLEC Gene
- UniProtKB/Swiss-Prot Function:
- Carbohydrate-binding protein with a strong ligand preference for Glc2-N-glycan. May play a role in the early steps of protein N-glycosylation (By similarity).
Phenotypes From GWAS Catalog for MLEC Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0019899 | enzyme binding | IPI | 22988243 |
| GO:0030246 | carbohydrate binding | IEA,ISS | -- |
Phenotypes for MLEC Gene
- MGI mutant phenotypes for MLEC:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for MLEC:
Animal Models for MLEC Gene
- MGI Knock Outs for MLEC:
-
- Mlec Mlec<tm1a(EUCOMM)Wtsi>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
-
OriGene CRISPR knockouts for MLEC
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MLEC
- genomics-online: gRNA clones - Search results for available MLEC gene related products
- Applied Biological Materials (abm): CRISPR Clones for MLEC - Select products 50% OFF >
- * MLEC CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * MLEC CRISPR applications: KO, Activation, Repression, and more - Browse All
-
Santa Cruz Biotechnology (SCBT) CRISPR for MLEC
miRNA for MLEC Gene
- miRTarBase miRNAs that target MLEC
-
- hsa-mir-24-3p (MIRT003889)
- hsa-mir-375 (MIRT019896)
- hsa-mir-124-3p (MIRT022943)
- hsa-mir-296-3p (MIRT038439)
- hsa-mir-25-3p (MIRT050275)
- hsa-mir-19a-3p (MIRT062706)
- hsa-mir-19b-3p (MIRT062707)
- hsa-mir-148a-3p (MIRT062708)
- hsa-mir-130a-3p (MIRT062709)
- hsa-mir-152-3p (MIRT062710)
- hsa-mir-301a-3p (MIRT062711)
- hsa-mir-130b-3p (MIRT062712)
- hsa-mir-148b-3p (MIRT062713)
- hsa-mir-495-3p (MIRT062714)
- hsa-mir-454-3p (MIRT062715)
- hsa-mir-301b-3p (MIRT062716)
- hsa-mir-548e-5p (MIRT062717)
- hsa-mir-548f-5p (MIRT062718)
- hsa-mir-548g-5p (MIRT062719)
- hsa-mir-548p (MIRT062720)
- hsa-mir-548x-5p (MIRT062721)
- hsa-mir-4295 (MIRT062722)
- hsa-mir-3666 (MIRT062723)
- hsa-mir-3925-5p (MIRT062724)
- hsa-mir-548aj-5p (MIRT062725)
- hsa-mir-548aw (MIRT062726)
- hsa-mir-5688 (MIRT062727)
- hsa-mir-101-3p (MIRT112563)
- hsa-mir-6840-3p (MIRT112574)
- hsa-mir-4797-5p (MIRT133303)
- hsa-mir-5571-5p (MIRT133304)
- hsa-mir-485-5p (MIRT440231)
- hsa-mir-1226-5p (MIRT473173)
- hsa-mir-1257 (MIRT473174)
- hsa-mir-6829-5p (MIRT473175)
- hsa-mir-6762-3p (MIRT473176)
- hsa-mir-3649 (MIRT473177)
- hsa-mir-4721 (MIRT473178)
- hsa-mir-3616-3p (MIRT473179)
- hsa-mir-4446-3p (MIRT473180)
- hsa-mir-4764-3p (MIRT513557)
- hsa-mir-151a-3p (MIRT535884)
- hsa-mir-3194-3p (MIRT535885)
- hsa-mir-298 (MIRT535886)
- hsa-mir-4680-5p (MIRT535887)
- hsa-mir-3158-5p (MIRT535888)
- hsa-mir-6787-3p (MIRT535889)
- hsa-mir-4267 (MIRT535890)
- hsa-mir-5685 (MIRT535891)
- hsa-mir-4690-3p (MIRT535892)
- hsa-mir-6501-3p (MIRT535893)
- hsa-mir-4463 (MIRT535894)
- hsa-mir-4499 (MIRT535895)
- hsa-mir-509-5p (MIRT535896)
- hsa-mir-509-3-5p (MIRT535897)
- hsa-mir-4418 (MIRT535898)
- hsa-mir-526b-5p (MIRT556115)
- hsa-mir-1468-3p (MIRT556116)
- hsa-mir-133a-3p (MIRT687546)
- hsa-mir-323a-5p (MIRT687547)
- hsa-mir-4281 (MIRT687548)
- hsa-mir-548v (MIRT687549)
- hsa-mir-3665 (MIRT687550)
- hsa-mir-139-5p (MIRT687551)
- hsa-mir-4673 (MIRT687552)
- hsa-mir-4645-5p (MIRT687553)
- hsa-mir-4692 (MIRT687554)
- hsa-mir-4514 (MIRT687555)
- hsa-mir-940 (MIRT687556)
- hsa-mir-6893-5p (MIRT687557)
- hsa-mir-6808-5p (MIRT687558)
- hsa-mir-144-3p (MIRT687559)
- hsa-mir-1249-5p (MIRT736441)
- hsa-mir-149-3p (MIRT737751)
- hsa-mir-3202 (MIRT741153)
- hsa-mir-4475 (MIRT745019)
- hsa-mir-4728-5p (MIRT747847)
- hsa-mir-4747-5p (MIRT748251)
- hsa-mir-5196-5p (MIRT750035)
- hsa-mir-545-3p (MIRT750453)
- hsa-mir-6785-5p (MIRT755842)
- hsa-mir-6797-5p (MIRT756201)
- hsa-mir-6825-5p (MIRT756995)
- hsa-mir-6828-5p (MIRT757077)
- hsa-mir-6883-5p (MIRT758427)
- hsa-mir-7515 (MIRT759385)
- hsa-mir-7845-5p (MIRT759801)
- hsa-mir-9500 (MIRT760890)
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for MLEC
- Browse OriGene Inhibitory RNA Products For MLEC
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MLEC
- genomics-online: shRNA clones - Search results for available MLEC gene related products
Clone Products
- Sino Biological Human cDNA Clone for MLEC
- Addgene plasmids for MLEC
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MLEC
- genomics-online: cdna clones - Search results for available MLEC gene related products
- orf clones - Search results for available MLEC gene related products
- Applied Biological Materials (abm): Clones for MLEC - Select products 50% OFF >
- * MLEC as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * MLEC tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
Cell Line Products
-
Horizon Cell Lines for MLEC
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for MLEC Gene
Localization for MLEC Gene
Subcellular locations from UniProtKB/Swiss-Prot for MLEC Gene
- Endoplasmic reticulum membrane; Single-pass type I membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 4 |
| endoplasmic reticulum | 4 |
| extracellular | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005783 | endoplasmic reticulum | ISS | -- |
| GO:0005789 | endoplasmic reticulum membrane | TAS | -- |
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0016020 | membrane | HDA,IEA | 19946888 |
| GO:0016021 | integral component of membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for MLEC Gene
Pathways & Interactions for MLEC Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Innate Immune System |
.61
|
|
| 2 | Metabolism of proteins | ||
| 3 | Transport to the Golgi and subsequent modification | ||
| 4 | Calnexin/calreticulin cycle | ||
Pathways by source for MLEC Gene
7 Reactome pathways for MLEC Gene
Interacting Proteins for MLEC Gene
GPS-Prot Interaction Network for MLEC
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005975 | carbohydrate metabolic process | IEA | -- |
| GO:0006457 | protein folding | TAS | -- |
| GO:0043312 | neutrophil degranulation | TAS | -- |
No data available for SIGNOR curated interactions for MLEC Gene
Drugs & Compounds for MLEC Gene
No Compound Related Data Available
Drug Products
- Creative Biomart Recombinant Human MLEC, His-tagged and Recombinant Human MLEC Protein, MYC/DDK-tagged
Transcripts for MLEC Gene
mRNA/cDNA for MLEC Gene
- (3) REFSEQ mRNAs :
- (16) Additional mRNA sequences :
- (786) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000228506 6341 bps (ENST00000228506.7)
- ENST00000412616 841 bps (ENST00000412616.2)
- ENST00000545525 549 bps (ENST00000545525.5)
- ENST00000535656 543 bps (ENST00000535656.1)
- ENST00000535413 617 bps (ENST00000535413.1)
CRISPR Products
-
OriGene CRISPR knockouts for MLEC
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MLEC
- genomics-online: gRNA clones - Search results for available MLEC gene related products
- Applied Biological Materials (abm): CRISPR Clones for MLEC - Select products 50% OFF >
- * MLEC CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * MLEC CRISPR applications: KO, Activation, Repression, and more - Browse All
-
Santa Cruz Biotechnology (SCBT) CRISPR for MLEC
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for MLEC
- Browse OriGene Inhibitory RNA Products For MLEC
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MLEC
- genomics-online: shRNA clones - Search results for available MLEC gene related products
Clone Products
- Sino Biological Human cDNA Clone for MLEC
- Addgene plasmids for MLEC
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MLEC
- genomics-online: cdna clones - Search results for available MLEC gene related products
- orf clones - Search results for available MLEC gene related products
- Applied Biological Materials (abm): Clones for MLEC - Select products 50% OFF >
- * MLEC as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * MLEC tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8a | · | 8b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||
| SP2: | |||||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||
| SP4: | - | ||||||||||||||||||||||
| SP5: | - |
Expression for MLEC Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Intestine (Gastrointestinal Tract)
-
Colon (Gastrointestinal Tract)
-
Prostate (Endocrine System)
-
Thyroid (Endocrine System)
-
Gall Bladder (Hepatobiliary System)
-
Kidney (Urinary System)
-
Testis (Reproductive System)
-
Adrenal Gland (Endocrine System)
-
Pancreas (Endocrine System)
-
Adipose (Muscoskeletal System)
This gene is overexpressed in Peripheral blood mononuclear cells (7.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for MLEC Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of MLEC Gene:
MLECSOURCE GeneReport for Unigene cluster for MLEC Gene:
Hs.744910Evidence on tissue expression from TISSUES for MLEC Gene
- Lung(4.8)
- Skin(4.8)
- Liver(4.5)
- Bone marrow(4.2)
- Nervous system(4.2)
- Intestine(4)
- Kidney(3.2)
- Eye(2.7)
- Heart(2.2)
- Pancreas(2.2)
Primer Products
-
OriGene qPCR primer pairs for MLEC
-
OriGene qPCR primer pairs and template standards for MLEC
- genomics-online: primer clones - Search results for available MLEC gene related products
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for MLEC Gene
Orthologs for MLEC Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | MLEC 33 32 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | MLEC 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | MLEC 33 32 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | MLEC 33 32 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Mlec 32 |
|
||
| mouse (Mus musculus) |
Mammalia | Mlec 17 33 32 |
|
||
| chicken (Gallus gallus) |
Aves | MLEC 33 32 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | MLEC 33 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | mlec 32 |
|
||
| Str.6941 32 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | kiaa0152-prov 32 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | mlec 33 32 |
|
OneToOne | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP007950 32 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG9257 33 32 |
|
OneToOne | |
| worm (Caenorhabditis elegans) |
Secernentea | F44E2.10 33 32 |
|
OneToOne | |
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.8086 33 |
|
OneToOne | |
| Cin.1179 32 |
|
||||
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.1179 32 |
|
- Species where no ortholog for MLEC was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Evolution for MLEC Gene
- ENSEMBL:
- Gene Tree for MLEC (if available)
- TreeFam:
- Gene Tree for MLEC (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for MLEC: view image
Paralogs for MLEC Gene
Pseudogenes.org Pseudogenes for MLEC Gene
No data available for Paralogs for MLEC Gene
Variants for MLEC Gene
| SNP ID | Clin | Chr 12 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000066995 | -- | 120,691,916(+) | T/C | 5_prime_UTR_variant, intron_variant | |
| rs1000293643 | -- | 120,691,532(+) | T/C | 5_prime_UTR_variant, intron_variant | |
| rs1000317612 | -- | 120,699,049(+) | G/C/T | 3_prime_UTR_variant | |
| rs1000586845 | -- | 120,696,798(+) | C/T | 3_prime_UTR_variant | |
| rs1000663938 | -- | 120,691,287(+) | C/T | 5_prime_UTR_variant, intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2659790 | CNV | deletion | 23128226 |
| esv3630929 | CNV | loss | 21293372 |
| nsv1045923 | CNV | gain | 25217958 |
| nsv521928 | CNV | gain | 19592680 |
Residual Variation Intolerance Score:
37% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.29;
6.49% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for MLEC Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MLEC
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MLEC Gene
Disorders for MLEC Gene
Additional Disease Information for MLEC
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for MLEC Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MLEC Gene
Publications for MLEC Gene
- Malectin forms a complex with ribophorin I for enhanced association with misfolded glycoproteins. (PMID: 22988243) Qin SY … Yamamoto K (The Journal of biological chemistry 2012) 2 3 56
- MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia. (PMID: 20347265) Xu Y … Liu P (Schizophrenia research 2010) 3 43 56
- Malectin: a novel carbohydrate-binding protein of the endoplasmic reticulum and a candidate player in the early steps of protein N-glycosylation. (PMID: 18524852) Schallus T … Muhle-Goll C (Molecular biology of the cell 2008) 2 3 56
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 56
- Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1. (PMID: 8590280) Nagase T … Nomura N (DNA research : an international journal for rapid publication of reports on genes and genomes 1995) 3 4 56
ExternalLinks
Products for MLEC Gene
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for MLEC
- Search Origene for MassSpec and Protein Over-expression Lysates for MLEC
- Origene Custom Protein Services for MLEC
- Origene sirna, shrna, and RNAi products in human, mouse, rat for MLEC
- Browse OriGene Inhibitory RNA Products For MLEC
- OriGene qPCR primer pairs for MLEC
- OriGene qPCR primer pairs and template standards for MLEC
- OriGene CRISPR knockouts for MLEC
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For MLEC
- Sino Biological Human cDNA Clone for MLEC
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
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- High-throughput Antibody Production Service
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- Epitope Tag Antibodies & Reporter Protein Antibodies
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- Novus Biologicals Antibodies for MLEC
- Novus Biologicals proteins and lysates for MLEC
- Browse Antibodies
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- Abcam antibodies for MLEC
- Abcam proteins for MLEC
- Find your target
- Browse Primary Antibodies
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- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
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- Addgene plasmids for MLEC
- antibodies-online: Show 12 available MLEC Antibodies ranked by validation data
- Compare Top MLEC Antibodies
- antibodies-online: Search results for available MLEC related products ranked by validation data
- antibodies-online: Show 9 available MLEC Proteins ranked by validation data
- Compare Top MLEC Proteins
- Quality Products:
- Horizon Cell Lines for MLEC
- genomics-online: cdna clones - Search results for available MLEC gene related products
- orf clones - Search results for available MLEC gene related products
- genomics-online: gRNA clones - Search results for available MLEC gene related products
- genomics-online: primer clones - Search results for available MLEC gene related products
- genomics-online: shRNA clones - Search results for available MLEC gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MLEC
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MLEC
- Search GeneCopoeia for miRNA 3'UTR Target clone products for MLEC
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MLEC
Sources for MLEC Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) CGAP SAGE
- (31) SOURCE
- (32) HomoloGene
- (33) PanEnsembl
- (34) euGenes
- (35) SGD
- (36) FlyBase
- (37) WormBase
- (38) Pseudogene
- (39) DGV
- (40) dbSNP
- (41) GenAtlas
- (42) HGMD
- (43) GAD
- (44) BGMUT
- (45) HuGE
- (46) Atlas
- (47) GenBank
- (48) H-invDB
- (49) HORDE
- (50) HUGE
- (51) IMGT
- (52) Leiden
- (53) miRBase
- (54) DME
- (55) OriGene
- (56) PubMed
- (57) R&D Systems
- (58) TGDB
- (59) Tocris
- (60) Abcam
- (61) Novus Biologicals
- (62) ProSpec
- (63) Sino Biological
- (64) GenScript
- (65) Qiagen
- (66) OCA
- (67) Proteopedia
- (68) MOPED
- (69) neXtProt
- (70) Reactome
- (71) GeneGo (Thomson Reuters)
- (72) DISEASES
- (73) SIMAP
- (74) GenomeRNAi
- (75) LifeMap
- (76) miRTarBase
- (77) MalaCards
- (78) Invitrogen
- (79) BitterDB
- (80) ESI-BIO
- (81) RefSeq
- (82) BioSystems
- (83) MaxQB
- (84) IUPHAR
- (85) BioGPS
- (86) Illumina
- (87) COMPARTMENTS
- (88) HOMER
- (89) PaxDb
- (90) ApexBio
- (91) Addgene
- (92) antibodies-online
- (93) CYP
- (94) NONCODE
- (95) TreeFam
- (96) PathCards
- (97) GeneReviews
- (98) GeneTex
- (99) Taconic Biosciences
- (100) GTEx
- (101) ProteomicsDB
- (102) SCBT
- (103) DGIdb
- (104) ClinicalTrials
- (105) RVIS
- (106) SIGNOR
- (107) diseasecard
- (108) NIH Rare Diseases
- (109) Orphanet
- (110) UMLS
- (111) GTR
- (112) Disease Ontology
- (113) Genetics Home Reference
- (114) MeSH
- (115) MedlinePlus
- (116) CDC
- (117) NINDS
- (118) NCBI Bookshelf
- (119) ClinVar
- (120) Gene Damage Index
- (121) HPO
- (122) UDN
- (123) VISTA
- (124) FANTOM5
- (125) ENCODE
- (126) ProSci
- (127) Horizon
- (128) NURSA
- (129) IID
- (130) VectorBuilder
- (131) SNPedia
- (132) BRCA Exchange
- (133) CIViC
- (134) ProteoGenix
- (135) dbSUPER
- (136) TISSUES
- (137) Gene ORGANizer
- (138) abm
- (139) Human Protein Atlas
- (140) GWAS Catalog
- (141) Monarch Initiative
- (142) DataMed
- (143) HumanCyc
- (144) genomics-online
- (145) UCNEbase
- (146) EPDnew
- (147) Applied Biosystems
- (148) GlyConnect
- (149) Aminode
- (150) GeneCopoeia
- (151) GPS-Prot
- (152) RNACentral
- (153) LncRNADisease
- (154) LOVD
- (155) miR2Disease
- (156) DiseaseEnhancer
- (157) Boster Bio
- (158) Biorbyt
- (159) Biocompare
- (160) Mastermind
- (161) CTD^2 Dashboard
- (162) CraniofacialAtlas
- (163) GeneImprint
- (164) Synthego
- (165) Bio Basic
- (166) ENA
- (167) GtRNAdb
- (168) LncBase
- (169) LncBook
- (170) LNCipedia
- (171) LncRNAdb
- (172) Modomics
- (173) PDBe
- (174) Rfam
- (175) SILVA
- (176) snOPY
- (177) SRPDB
- (178) GENCODE
- (179) TarBase
- (180) MyBioSource