Aliases for MKRN3 Gene
External Ids for MKRN3 Gene
Previous HGNC Symbols for MKRN3 Gene
Previous GeneCards Identifiers for MKRN3 Gene
The protein encoded by this gene contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. This gene is intronless and imprinted, with expression only from the paternal allele. Disruption of the imprinting at this locus may contribute to Prader-Willi syndrome. An antisense RNA of unknown function has been found overlapping this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for MKRN3 Gene
MKRN3 (Makorin Ring Finger Protein 3) is a Protein Coding gene. Diseases associated with MKRN3 include Precocious Puberty, Central, 2 and Idiopathic Central Precocious Puberty. Gene Ontology (GO) annotations related to this gene include ligase activity. An important paralog of this gene is MKRN1.
UniProtKB/Swiss-Prot Summary for MKRN3 Gene
E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.