Aliases for MISP3 Gene

Aliases for MISP3 Gene

  • MISP Family Member 3 2 3 4 5
  • Uncharacterized Protein MISP3 3 4
  • MISP3 5

External Ids for MISP3 Gene

Summaries for MISP3 Gene

GeneCards Summary for MISP3 Gene

MISP3 (MISP Family Member 3) is a Protein Coding gene. An important paralog of this gene is MISP.

Additional gene information for MISP3 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MISP3 Gene

Genomics for MISP3 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MISP3 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J014071 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 600.7 +1.1 1131 4.3 HNRNPL GATAD2A CTCF ZBTB33 TEAD4 PRDM10 ZNF629 TFE3 IKZF1 ZNF692 MIR1199 MISP3 PALM3 ASF1B DDX39A DCAF15 PRKACA CCDC130 RFX1 TRMT1
GH19J014072 Enhancer 0.2 dbSUPER 600.7 -1.2 -1214 0.3 EEF1DP1 MISP3 PALM3 RF00017-2840
GH19J013879 Promoter/Enhancer 1.6 Ensembl ENCODE CraniofacialAtlas 12.8 -191.1 -191057 3.5 ZNF221 SP1 HNRNPL CREB1 GATAD2A CTCF TEAD4 PRDM10 ZNF629 TFE3 piR-35674-248 CC2D1A C19orf57 PALM3 EEF1DP1 MISP3 NANOS3
GH19J013884 Promoter/Enhancer 1.2 FANTOM5 Ensembl ENCODE 12.8 -186.3 -186296 3.1 ZBTB33 IKZF1 RFX1 ZIC2 ZNF341 BMI1 ZNF592 KLF4 PKNOX1 ZNF217 CC2D1A C19orf57 PALM3 EEF1DP1 MISP3 IL27RA CCDC130 DCAF15 piR-35674-248 NANOS3
GH19J013883 Enhancer 0.5 ENCODE 12.8 -188.7 -188683 0.1 CTCF IKZF1 ZNF687 HSF1 ZNF143 ZNF652 C19orf57 CC2D1A PALM3 EEF1DP1 MISP3 piR-35674-248 NANOS3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MISP3 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for MISP3

Genomic Locations for MISP3 Gene

Genomic Locations for MISP3 Gene
2,527 bases
Plus strand
2,054 bases
Plus strand

Genomic View for MISP3 Gene

Genes around MISP3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MISP3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MISP3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MISP3 Gene

Proteins for MISP3 Gene

  • Protein details for MISP3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Uncharacterized protein MISP3
    Protein Accession:

    Protein attributes for MISP3 Gene

    219 amino acids
    Molecular mass:
    24028 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MISP3 Gene

Post-translational modifications for MISP3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MISP3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MISP3 Gene

Domains & Families for MISP3 Gene

Gene Families for MISP3 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for MISP3 Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the MISP family.
  • Belongs to the MISP family.
genes like me logo Genes that share domains with MISP3: view

No data available for Suggested Antigen Peptide Sequences for MISP3 Gene

Function for MISP3 Gene

Phenotypes From GWAS Catalog for MISP3 Gene

Phenotypes for MISP3 Gene

genes like me logo Genes that share phenotypes with MISP3: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MISP3 Gene

Localization for MISP3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MISP3 Gene

Pathways & Interactions for MISP3 Gene

PathCards logo

SuperPathways for MISP3 Gene

No Data Available

Interacting Proteins for MISP3 Gene

Gene Ontology (GO) - Biological Process for MISP3 Gene


No data available for Pathways by source and SIGNOR curated interactions for MISP3 Gene

Drugs & Compounds for MISP3 Gene

No Compound Related Data Available

Transcripts for MISP3 Gene

mRNA/cDNA for MISP3 Gene

2 NCBI additional mRNA sequence :
4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MISP3

Alternative Splicing Database (ASD) splice patterns (SP) for MISP3 Gene

No ASD Table

Relevant External Links for MISP3 Gene

GeneLoc Exon Structure for

Expression for MISP3 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MISP3

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MISP3 Gene

Orthologs for MISP3 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MISP3 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-1199 31
  • 99 (a)
(Mus musculus)
Mammalia 2210011C24Rik 31
  • 74 (a)
(Canis familiaris)
Mammalia cfa-mir-1199 31
  • 70 (a)
(Bos Taurus)
Mammalia -- 31
  • 67 (a)
(Ornithorhynchus anatinus)
Mammalia -- 31
  • 38 (a)
Species where no ortholog for MISP3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for MISP3 Gene

Gene Tree for MISP3 (if available)
Gene Tree for MISP3 (if available)

Paralogs for MISP3 Gene

Paralogs for MISP3 Gene

genes like me logo Genes that share paralogs with MISP3: view

Variants for MISP3 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MISP3 Gene

SNP ID Clinical significance and condition Chr 19 pos Variation AA Info Type
rs7258963 - p.Val198Ala

Additional dbSNP identifiers (rs#s) for MISP3 Gene

Structural Variations from Database of Genomic Variants (DGV) for MISP3 Gene

Variant ID Type Subtype PubMed ID
dgv49n68 CNV loss 17160897
nsv578642 CNV gain 21841781
nsv828452 CNV loss 20364138
nsv828454 CNV gain 20364138
nsv833761 CNV loss 17160897

Additional Variant Information for MISP3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MISP3 Gene

Disorders for MISP3 Gene

No disorders were found for MISP3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MISP3 Gene

Publications for MISP3 Gene

  1. MISP is a novel Plk1 substrate required for proper spindle orientation and mitotic progression. (PMID: 23509069) Zhu M … Hoffmann I (The Journal of cell biology 2013) 2 3
  2. Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation. (PMID: 30948266) Lee SH … Mayr C (Molecular cell 2019) 3
  3. Quantitative mapping of RNA-mediated nuclear estrogen receptor β interactome in human breast cancer cells. (PMID: 29509190) Giurato G … Tarallo R (Scientific data 2018) 3
  4. FOXA1 Directs H3K4 Monomethylation at Enhancers via Recruitment of the Methyltransferase MLL3. (PMID: 27926873) Jozwik KM … Carroll JS (Cell reports 2016) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4

Products for MISP3 Gene

Sources for MISP3 Gene