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Aliases for MIRLET7BHG Gene

Subcategory (RNA class) for MIRLET7BHG Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIRLET7BHG Gene

  • MIRLET7B Host Gene 2 3 5
  • MIRLET7B Host Gene (Non-Protein Coding) 2 3
  • Linc-Ppara 3

External Ids for MIRLET7BHG Gene

Previous GeneCards Identifiers for MIRLET7BHG Gene

  • GC00U927125
  • GC22P046482

Summaries for MIRLET7BHG Gene

GeneCards Summary for MIRLET7BHG Gene

MIRLET7BHG (MIRLET7B Host Gene) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Metastatic brain tumor.

Additional gene information for MIRLET7BHG Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIRLET7BHG Gene

Genomics for MIRLET7BHG Gene

GeneHancer (GH) Regulatory Elements for MIRLET7BHG Gene

Promoters and enhancers for MIRLET7BHG Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22I046006 Promoter/Enhancer 2.2 FANTOM5 Ensembl ENCODE dbSUPER 12.5 -43.1 -43128 9.5 HDGF PKNOX1 FOXA2 ARID4B SIN3A DMAP1 ZNF2 YY1 POLR2B ZNF213 LINC00899 CDPF1 TRMU ENSG00000273243 LOC642648 MIRLET7BHG PRR34-AS1 PRR34 ENSG00000231010 NUP50
GH22I046000 Enhancer 1.1 Ensembl ENCODE dbSUPER 12.1 -51.4 -51410 3.1 BCOR HDAC1 KLF17 ZMYM3 ZIC2 ZFHX2 GLIS2 ZBTB48 PATZ1 PRDM10 LINC00899 LOC642648 MIRLET7BHG PRR34 PRR34-AS1 ENSG00000231010 GC22M045913 LOC730668
GH22I046022 Enhancer 0.9 ENCODE dbSUPER 12.7 -30.0 -30001 1.8 ZBTB21 KLF17 SALL2 ZNF398 ZIC2 HIC1 ZNF664 ZFHX2 JUND ZNF366 LINC00899 LOC642648 PRR34-AS1 ENSG00000231010 MIRLET7BHG PRR34 ENSG00000273287 ENSG00000273145 GC22M046033
GH22I046096 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 6.4 +50.1 50061 14.9 FOXA2 ARID4B ZNF48 YY1 GLIS2 SP3 RXRA YY2 PPARG KAT8 MIRLET7BHG PPARA PRR34 GC22M046089 MIR3619
GH22I046004 Enhancer 0.7 ENCODE dbSUPER 12.1 -49.4 -49372 0.7 GLIS1 ZMYM3 KDM1A FOS LINC00899 LOC642648 MIRLET7BHG PRR34 PRR34-AS1 ENSG00000231010 GC22M045913 LOC730668
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIRLET7BHG on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIRLET7BHG Gene

Genomic Locations for MIRLET7BHG Gene
chr22:46,053,869-46,113,928
(GRCh38/hg38)
Size:
60,060 bases
Orientation:
Plus strand
chr22:46,449,749-46,509,808
(GRCh37/hg19)

Genomic View for MIRLET7BHG Gene

Genes around MIRLET7BHG on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIRLET7BHG Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIRLET7BHG Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIRLET7BHG Gene

Proteins for MIRLET7BHG Gene

Post-translational modifications for MIRLET7BHG Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIRLET7BHG Gene

Domains & Families for MIRLET7BHG Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIRLET7BHG Gene

Function for MIRLET7BHG Gene

Phenotypes From GWAS Catalog for MIRLET7BHG Gene

Animal Model Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIRLET7BHG Gene

Localization for MIRLET7BHG Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIRLET7BHG Gene

Pathways & Interactions for MIRLET7BHG Gene

SuperPathways for MIRLET7BHG Gene

SuperPathway Contained pathways
1 Metastatic brain tumor
genes like me logo Genes that share pathways with MIRLET7BHG: view

Pathways by source for MIRLET7BHG Gene

1 BioSystems pathway for MIRLET7BHG Gene

Interacting Proteins for MIRLET7BHG Gene

Gene Ontology (GO) - Biological Process for MIRLET7BHG Gene

None

No data available for SIGNOR curated interactions for MIRLET7BHG Gene

Drugs & Compounds for MIRLET7BHG Gene

No Compound Related Data Available

Transcripts for MIRLET7BHG Gene

mRNA/cDNA for MIRLET7BHG Gene

Unigene Clusters for MIRLET7BHG Gene

MIRLET7B host gene (non-protein coding):
Representative Sequences:

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIRLET7BHG Gene

No ASD Table

Relevant External Links for MIRLET7BHG Gene

GeneLoc Exon Structure for
MIRLET7BHG
ECgene alternative splicing isoforms for
MIRLET7BHG

Expression for MIRLET7BHG Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIRLET7BHG Gene

NURSA nuclear receptor signaling pathways regulating expression of MIRLET7BHG Gene:

MIRLET7BHG

SOURCE GeneReport for Unigene cluster for MIRLET7BHG Gene:

Hs.235838
genes like me logo Genes that share expression patterns with MIRLET7BHG: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIRLET7BHG Gene

Orthologs for MIRLET7BHG Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIRLET7BHG Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 34
  • 96 (a)
OneToOne
Species where no ortholog for MIRLET7BHG was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIRLET7BHG Gene

ENSEMBL:
Gene Tree for MIRLET7BHG (if available)
TreeFam:
Gene Tree for MIRLET7BHG (if available)

Paralogs for MIRLET7BHG Gene

No data available for Paralogs for MIRLET7BHG Gene

Variants for MIRLET7BHG Gene

Sequence variations from dbSNP and Humsavar for MIRLET7BHG Gene

SNP ID Clin Chr 22 pos Variation AA Info Type
rs1000099401 -- 46,090,602(+) C/T intron_variant
rs1000147563 -- 46,093,822(+) T/C intron_variant
rs1000387129 -- 46,099,279(+) C/T intron_variant
rs1000473900 -- 46,111,466(+) C/T non_coding_transcript_variant
rs1000484364 -- 46,089,758(+) C/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for MIRLET7BHG Gene

Variant ID Type Subtype PubMed ID
nsv834224 CNV loss 17160897
nsv829285 CNV gain 20364138
nsv829281 CNV gain 20364138
nsv589133 CNV loss 21841781
nsv589132 CNV loss 21841781
nsv516279 CNV loss 19592680
nsv471213 CNV gain 18288195
nsv471212 CNV loss 18288195
nsv459905 CNV loss 19166990
nsv459904 CNV loss 19166990
nsv1152661 OTHER inversion 26484159
esv3438171 CNV insertion 20981092
esv3307110 CNV mobile element insertion 20981092
esv2724423 CNV deletion 23290073
esv2661950 CNV deletion 23128226
esv25384 CNV gain 19812545
esv1346561 CNV insertion 17803354
esv1011338 CNV deletion 20482838
dgv8124n54 CNV loss 21841781
dgv777n67 CNV gain 20364138
dgv776n67 CNV gain 20364138
dgv2469n106 OTHER inversion 24896259

Additional Variant Information for MIRLET7BHG Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIRLET7BHG

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIRLET7BHG Gene

Disorders for MIRLET7BHG Gene

Additional Disease Information for MIRLET7BHG

No disorders were found for MIRLET7BHG Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIRLET7BHG Gene

Publications for MIRLET7BHG Gene

  1. Multiple knockout mouse models reveal lincRNAs are required for life and brain development. (PMID: 24381249) Sauvageau M … Rinn JL (eLife 2013) 2 3 58
  2. Cytoplasmic sequestration of HDAC7 from mitochondrial and nuclear compartments upon initiation of apoptosis. (PMID: 15364908) Bakin RE … Jung MO (The Journal of biological chemistry 2004) 2 3 58
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58
  4. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo MF … Soares MB (Genome research 1996) 3 58
  5. RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. (PMID: 29117863) Choudhury NR … Michlewski G (BMC biology 2017) 3

Products for MIRLET7BHG Gene

Sources for MIRLET7BHG Gene

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