microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR942 Gene

Subcategory (RNA class) for MIR942 Gene

miRNA

Number of RNA Genes sources:

5 / 17

Aliases for MIR942 Gene

  • MicroRNA 942 2 3 5
  • Hsa-MiR-942-5p 163 173
  • Hsa-Mir-942 2 3
  • MIR942 2 5
  • Hsa-MiR-942-3p 163
  • MIMAT0004985 50
  • MIMAT0026734 50
  • MI0005767 50
  • MIRN942 3
  • Mir-942 3
  • RF00997 168

External Ids for MIR942 Gene

Previous HGNC Symbols for MIR942 Gene

  • MIRN942

Previous GeneCards Identifiers for MIR942 Gene

  • GC01P117440
  • GC01P117637

Summaries for MIR942 Gene

Entrez Gene Summary for MIR942 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR942 Gene

MIR942 (MicroRNA 942) is an RNA Gene, and is affiliated with the miRNA class.

Rfam classification for MIR942 Gene

Additional gene information for MIR942 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR942 Gene

Genomics for MIR942 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR942 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J117091 Enhancer 1.2 Ensembl ENCODE CraniofacialAtlas 600.7 +0.4 425 6.4 CTCF TEAD4 PRDM10 ZNF629 RFX1 LEF1 ZNF692 JUND PHF21A ZIC2 MIR942 lnc-TTF2-2 TRIM45 TTF2
GH01J117128 Enhancer 0.9 Ensembl CraniofacialAtlas 10.4 +34.0 33958 1.6 CTCF ZNF692 REST RAD21 CEBPB NFE2 ZNF316 ZBTB40 SMC3 MAFG HSALNG0006372 MIR942 TTF2 MAN1A2 VTCN1 TRIM45 RPS15AP9
GH01J117071 Enhancer 0.7 Ensembl ENCODE 11.5 -24.4 -24353 0.2 IKZF2 DPF2 JUNB BATF EBF1 ATF2 TBX21 ATF7 MTA2 ZNF687 MIR942 TRIM45 LOC101929099 TTF2
GH01J117069 Enhancer 0.6 Ensembl ENCODE 11.5 -24.9 -24930 0.6 IKZF2 DPF2 ESRRA ATF2 TBX21 MTA2 MIR942 TRIM45 TTF2 LOC101929099
GH01J117070 Enhancer 0.5 ENCODE 11.5 -24.1 -24149 0.2 IKZF2 DPF2 ATF2 TBX21 MTA2 ZNF687 CREM MIR942 TRIM45 LOC101929099 TTF2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR942 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR942 Gene

Genomic Locations for MIR942 Gene
chr1:117,094,643-117,094,728
(GRCh38/hg38)
Size:
86 bases
Orientation:
Plus strand
chr1:117,637,265-117,637,350
(GRCh37/hg19)
Size:
86 bases
Orientation:
Plus strand

Genomic View for MIR942 Gene

Genes around MIR942 on UCSC Golden Path with GeneCards custom track
MIR942 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MIR942 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR942 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR942 Gene

Proteins for MIR942 Gene

Post-translational modifications for MIR942 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR942 Gene

Domains & Families for MIR942 Gene

Gene Families for MIR942 Gene

HGNC:
genes like me logo Genes that share domains with MIR942: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR942 Gene

Function for MIR942 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR942 Gene

Localization for MIR942 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR942 Gene

Pathways & Interactions for MIR942 Gene

PathCards logo

SuperPathways for MIR942 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR942 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035195 gene silencing by miRNA IEA --
genes like me logo Genes that share ontologies with MIR942: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR942 Gene

Drugs & Compounds for MIR942 Gene

No Compound Related Data Available

Transcripts for MIR942 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR942 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS0000712C24_9606 precursor_RNA 86 6

HGNC: 33688,

RefSeq: NR_030640,

Ensembl: ENST00000401111 (view in UCSC) ,

miRBase: MI0005767,

Rfam: RF00997,

ENA: LM609999.1:1..86:precursor_RNA,

URS00005194EC_9606 miRNA 22 5

RefSeq: NR_030640,

LncBase: hsa-miR-942-5p,

miRBase: MIMAT0004985,

TarBase: hsa-miR-942-5p,

ENA: LM380530.1:1..22:ncRNA, LM609999.1:13..34:ncRNA,

URS000075C646_9606 miRNA 22 4

RefSeq: NR_030640,

LncBase: hsa-miR-942-3p,

miRBase: MIMAT0026734,

ENA: LM383201.1:1..22:ncRNA, LM609999.1:53..74:ncRNA,

MIR942 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR942 Gene

1 NCBI additional mRNA sequence :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR942 Gene

No ASD Table

Relevant External Links for MIR942 Gene

GeneLoc Exon Structure for
MIR942

Expression for MIR942 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR942 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR942

genes like me logo Genes that share expression patterns with MIR942: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR942 Gene

Orthologs for MIR942 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR942 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-942 31
  • 100 (a)
OneToOne
Species where no ortholog for MIR942 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • Cow (Bos Taurus)
  • Dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Lizard (Anolis carolinensis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Mouse (Mus musculus)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Platypus (Ornithorhynchus anatinus)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rat (Rattus norvegicus)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)
  • Zebrafish (Danio rerio)

Evolution for MIR942 Gene

ENSEMBL:
Gene Tree for MIR942 (if available)
TreeFam:
Gene Tree for MIR942 (if available)

Paralogs for MIR942 Gene

No data available for Paralogs for MIR942 Gene

Variants for MIR942 Gene

Additional dbSNP identifiers (rs#s) for MIR942 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR942 Gene

Variant ID Type Subtype PubMed ID
nsv1009706 CNV gain 25217958

Additional Variant Information for MIR942 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR942

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR942 Gene

Disorders for MIR942 Gene

Additional Disease Information for MIR942

No disorders were found for MIR942 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR942 Gene

Publications for MIR942 Gene

  1. LncRNA ZEB1-AS1 facilitates ox-LDL-induced damage of HCtAEC cells and the oxidative stress and inflammatory events of THP-1 cells via miR-942/HMGB1 signaling. (PMID: 31962131) Hua Z … Li Z (Life sciences 2020) 3
  2. LINC00461 affects the survival of patients with renal cell carcinoma by acting as a competing endogenous RNA for microRNA‑942. (PMID: 31545458) Chen Y … Ding G (Oncology reports 2019) 3
  3. Hsa-miR-942 fingerprint in colorectal cancer through Wnt signaling pathway. (PMID: 31278963) Fasihi A … Nasiri S (Gene 2019) 3
  4. MiR-942-3p Promotes the Proliferation and Invasion of Hepatocellular Carcinoma Cells by Targeting MBL2. (PMID: 31046434) Xu CY … Fu ZR (Cancer control : journal of the Moffitt Cancer Center 2019) 3
  5. miR-942 promotes tumor migration, invasion, and angiogenesis by regulating EMT via BARX2 in non-small-cell lung cancer. (PMID: 31236953) Yang F … Shen H (Journal of cellular physiology 2019) 3

Products for MIR942 Gene

Sources for MIR942 Gene