microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The ... See more...

Aliases for MIR941-1 Gene

Data sources for MIR941-1 Gene:

Subcategory (RNA class) for MIR941-1 Gene

miRNA

Aliases for MIR941-1 Gene

External Ids for MIR941-1 Gene

Previous HGNC Symbols for MIR941-1 Gene

  • MIRN941-1

Previous GeneCards Identifiers for MIR941-1 Gene

  • GC20P062040
  • GC20P062050
  • GC20P062551
  • GC20P059284
  • GC20P063922
  • GC20P063952
  • GC20P064166
  • GC20P064189
  • GC20P064194
  • GC20P064251
  • GC20P063988
  • GC20P064008
  • GC20P064028
  • GC20P064044
  • GC20P064069
  • GC20P064093
  • GC20P064115
  • GC20P064141
  • GC20P064326

Summaries for MIR941-1 Gene

Entrez Gene Summary for MIR941-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR941-1 Gene

MIR941-1 (MicroRNA 941-1) is an RNA Gene, and is affiliated with the miRNA class.

Rfam classification for MIR941-1 Gene

Additional gene information for MIR941-1 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR941-1 Gene

Genomics for MIR941-1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MIR941-1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH20J063917 Enhancer 0.2 Ensembl 250.7 -1.7 -1748 0.2 MIR941-1 MIR941-2 MIR941-3 RF00907-001 RNU1-134P RF00003-051 DNAJC5 lnc-DNAJC5-1 UCKL1
GH20J063912 Enhancer 0.8 ENCODE dbSUPER 9.7 -6.3 -6316 0.9 ZNF217 CTBP1 SIN3A POLR2A FOXA1 PKNOX1 SCRT1 DPF2 CREB1 KLF1 MIR941-1 RF00003-051 RNU1-134P RF00907-001 DNAJC5 lnc-DNAJC5-1 UCKL1
GH20J063902 Enhancer 0.6 ENCODE dbSUPER 9.6 -16.2 -16219 1.6 JUND SPI1 KLF1 KLF17 FNDC11 SRMS ZBTB46 ZBTB46-AS1 ENSG00000229299 C20orf181 OPRL1 RGS19 LKAAEAR1 MIR941-1
GH20J063910 Enhancer 0.6 ENCODE dbSUPER 8.9 -8.1 -8085 1.6 SIN3A FOSL2 ZNF687 MNT MIR941-1 RF00003-051 RNU1-134P RF00907-001 DNAJC5 lnc-DNAJC5-1 UCKL1
GH20J063904 Enhancer 0.5 dbSUPER 9.6 -18.0 -17991 0.6 ZNF341 RBM22 POLR2A ZBTB17 RBFOX2 FNDC11 SRMS ZBTB46 ZBTB46-AS1 ENSG00000229299 C20orf181 OPRL1 RGS19 LKAAEAR1 MIR941-1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MIR941-1 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MIR941-1 Gene

Latest Assembly
chr20:63,919,449-63,919,520
(GRCh38/hg38)
Size:
72 bases
Orientation:
Plus strand

Previous Assembly
chr20:62,550,802-62,550,873
(GRCh37/hg19 by Entrez Gene)
Size:
72 bases
Orientation:
Plus strand

Genomic View for MIR941-1 Gene

Genes around MIR941-1 on UCSC Golden Path with GeneCards custom track
MIR941-1 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MIR941-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR941-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR941-1 Gene

Proteins for MIR941-1 Gene

Post-translational modifications for MIR941-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR941-1 Gene

Domains & Families for MIR941-1 Gene

Gene Families for MIR941-1 Gene

HGNC:
genes like me logo Genes that share domains with MIR941-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MIR941-1 Gene

Function for MIR941-1 Gene

Phenotypes From GWAS Catalog for MIR941-1 Gene

CRISPR products for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR941-1 Gene

Localization for MIR941-1 Gene

Gene Ontology (GO) - Cellular Components for MIR941-1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space HDA 26646931
genes like me logo Genes that share ontologies with MIR941-1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR941-1 Gene

Pathways & Interactions for MIR941-1 Gene

PathCards logo

SuperPathways for MIR941-1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MIR941-1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MIR941-1 Gene

Drugs & Compounds for MIR941-1 Gene

No Compound Related Data Available

Transcripts for MIR941-1 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MIR941-1 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000050E4BA_9606 miRNA 23 5

RefSeq: NR_030637, NR_030638, NR_030639, NR_040032, NR_128719,

LncBase: hsa-miR-941,

miRBase: MIMAT0004984,

TarBase: hsa-miR-941,

ENA: View 6 records in RNAcentral

URS00007B97D3_9606 precursor_RNA 72 4

RefSeq: NR_030637,

Ensembl: ENST00000636396 (view in UCSC) ,

miRBase: MI0005763,

ENA: LM609995.1:1..72:precursor_RNA,

URS0000644074_9606 precursor_RNA 89 1

Rfam: RF00907,

URS0001BC84D6_9606 pre_miRNA 89 1

Rfam: RF00907,

MIR941-1 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MIR941-1 Gene

1 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR941-1 Gene

No ASD Table

Relevant External Links for MIR941-1 Gene

GeneLoc Exon Structure for
MIR941-1

Expression for MIR941-1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR941-1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MIR941-1

genes like me logo Genes that share expression patterns with MIR941-1: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR941-1 Gene

Orthologs for MIR941-1 Gene

Evolution for MIR941-1 Gene

ENSEMBL:
Gene Tree for MIR941-1 (if available)
TreeFam:
Gene Tree for MIR941-1 (if available)

No data available for Orthologs for MIR941-1 Gene

Paralogs for MIR941-1 Gene

No data available for Paralogs for MIR941-1 Gene

Variants for MIR941-1 Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MIR941-1 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MIR941-1 Gene

Variant ID Type Subtype PubMed ID
nsv428381 CNV gain+loss 18775914
nsv469773 CNV gain 16826518
nsv509784 CNV insertion 20534489
nsv9829 CNV gain 18304495

Additional Variant Information for MIR941-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR941-1

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for MIR941-1 Gene

Disorders for MIR941-1 Gene

Additional Disease Information for MIR941-1

No disorders were found for MIR941-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR941-1 Gene

Publications for MIR941-1 Gene

  1. Direct evidence for transport of RNA from the mouse brain to the germline and offspring. (PMID: 32354330) O'Brien EA … Barry G (BMC biology 2020) 3
  2. miR-941 as a promising biomarker for acute coronary syndrome. (PMID: 28830367) Bai R … Chen K (BMC cardiovascular disorders 2017) 3
  3. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3
  4. Epigenetically regulated MIR941 and MIR1247 target gastric cancer cell growth and migration. (PMID: 24785261) Kim JG … Yi JM (Epigenetics 2014) 3
  5. Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. (PMID: 23535732) Eeles RA … Easton DF (Nature genetics 2013) 3

Products for MIR941-1 Gene

Sources for MIR941-1 Gene