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Aliases for MIR939 Gene

Subcategory (RNA class) for MIR939 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR939 Gene

  • MicroRNA 939 2 3 5
  • Hsa-Mir-939 3
  • Mir-939 3
  • MIRN939 3

External Ids for MIR939 Gene

Previous HGNC Symbols for MIR939 Gene

  • MIRN939

Previous GeneCards Identifiers for MIR939 Gene

  • GC08M145592
  • GC08M145621
  • GC08M145626
  • GC08M145627
  • GC08M140732
  • GC08M145630
  • GC08M145631
  • GC08M145632
  • GC08M145633

Summaries for MIR939 Gene

Entrez Gene Summary for MIR939 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR939 Gene

MIR939 (MicroRNA 939) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are mRNA Splicing - Major Pathway and RNA Polymerase II Transcription Termination.

Additional gene information for MIR939 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR939 Gene

Genomics for MIR939 Gene

GeneHancer (GH) Regulatory Elements for MIR939 Gene

Promoters and enhancers for MIR939 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08I144372 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 0.3 +20.3 20263 3 HDGF PKNOX1 ARID4B SIN3A DMAP1 ZBTB7B YY1 POLR2B CBX5 ZNF207 LOC101928902 ADCK5 CPSF1 LRRC14 ZNF517 TONSL DGAT1 MIR939 GC08P144288
GH08I144391 Enhancer 0.6 ENCODE 0.8 +2.6 2632 1 ZNF687 MAZ NFIB MNT CTBP1 ZBTB33 ZNF444 MYC VPS28 MIR939 ADCK5 GC08P144288
GH08I144396 Enhancer 0.6 ENCODE 0.8 -2.8 -2841 0.2 HDGF KLF1 SP2 REST SP1 POLR2A VEZF1 KLF9 PRDM10 ZBTB33 CPSF1 MIR939 MIR1234 GC08P144288
GH08I144386 Enhancer 0.8 ENCODE 0.4 +7.1 7076 1.6 SOX13 PKNOX1 TFAP4 FOXA2 SAP130 EBF1 FEZF1 ZBTB40 RARA HIC1 CPSF1 VPS28 TONSL-AS1 TONSL DGAT1 ENSG00000254690 HSF1 BOP1 MAF1 WDR97
GH08I144375 Enhancer 0.3 ENCODE 0.4 +18.6 18626 0.1 BCOR ADCK5 MIR939 GC08P144288
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR939 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR939 Gene

Genomic Locations for MIR939 Gene
chr8:144,394,149-144,394,230
(GRCh38/hg38)
Size:
82 bases
Orientation:
Minus strand
chr8:145,619,364-145,619,445
(GRCh37/hg19)

Genomic View for MIR939 Gene

Genes around MIR939 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR939 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR939 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR939 Gene

ORGUL Member Location for MIR939 Gene

ORGUL Member Location for MIR939 gene

Proteins for MIR939 Gene

Post-translational modifications for MIR939 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR939 Gene

Domains & Families for MIR939 Gene

Gene Families for MIR939 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR939: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR939 Gene

Function for MIR939 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR939 Gene

Localization for MIR939 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR939 Gene

Drugs & Compounds for MIR939 Gene

No Compound Related Data Available

Transcripts for MIR939 Gene

mRNA/cDNA for MIR939 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR939 Gene

No ASD Table

Relevant External Links for MIR939 Gene

GeneLoc Exon Structure for
MIR939
ECgene alternative splicing isoforms for
MIR939

Expression for MIR939 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR939 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR939 Gene:

MIR939
genes like me logo Genes that share expression patterns with MIR939: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR939 Gene

Orthologs for MIR939 Gene

Evolution for MIR939 Gene

ENSEMBL:
Gene Tree for MIR939 (if available)
TreeFam:
Gene Tree for MIR939 (if available)

No data available for Orthologs for MIR939 Gene

Paralogs for MIR939 Gene

No data available for Paralogs for MIR939 Gene

Variants for MIR939 Gene

Sequence variations from dbSNP and Humsavar for MIR939 Gene

SNP ID Clin Chr 08 pos Variation AA Info Type
rs1007267613 -- 144,396,178(-) G/A upstream_transcript_variant
rs1011447019 -- 144,395,923(-) G/A upstream_transcript_variant
rs1016420747 -- 144,396,179(-) G/A upstream_transcript_variant
rs1018406221 -- 144,396,053(-) C/G upstream_transcript_variant
rs1019909665 -- 144,395,643(-) C/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR939 Gene

Variant ID Type Subtype PubMed ID
dgv12434n54 CNV loss 21841781
dgv12437n54 CNV loss 21841781
esv2759652 CNV gain+loss 17122850
nsv428208 CNV gain 18775914
nsv470249 CNV loss 18288195
nsv515809 CNV gain+loss 19592680
nsv612934 CNV loss 21841781
nsv824805 CNV gain 20364138
nsv831489 CNV loss 17160897

Additional Variant Information for MIR939 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR939

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR939 Gene

Disorders for MIR939 Gene

Additional Disease Information for MIR939

No disorders were found for MIR939 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR939 Gene

Publications for MIR939 Gene

  1. Breast cancer-secreted miR-939 downregulates VE-cadherin and destroys the barrier function of endothelial monolayers. (PMID: 27693459) Di Modica M … Triulzi T (Cancer letters 2017) 3 58
  2. Decreased expression of miR-939 contributes to chemoresistance and metastasis of gastric cancer via dysregulation of SLC34A2 and Raf/MEK/ERK pathway. (PMID: 28114937) Zhang JX … Ye S (Molecular cancer 2017) 3 58
  3. MicroRNA-939 governs vascular integrity and angiogenesis through targeting γ-catenin in endothelial cells. (PMID: 28115160) Hou S … Li X (Biochemical and biophysical research communications 2017) 3 58
  4. Overexpression of hsa-miR-939 follows by NGFR down-regulation and apoptosis reduction. (PMID: 28229962) Aghdaei FH … Soleimani M (Journal of biosciences 2017) 3 58
  5. MicroRNA-939 down-regulates CD2-associated protein by targeting promoter in HEK-293T cells. (PMID: 26895305) Huang YP … Zhou GP (Renal failure 2016) 3 58

Products for MIR939 Gene

Sources for MIR939 Gene

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